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MGI:Mbtps1

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Mbtps1 ( synonyms: S1P, site-1 protease, SKI-1, subtilisin/kexin isozyme-1 )
Protein Name(s) membrane-bound transcription factor peptidase, site 1,
External Links
MGI MGI:1927235

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0004175

endopeptidase activity

MGI:MGI:3611598
PMID:15938716[1]

IDA: Inferred from Direct Assay

F

From MGI

GO:0004252

serine-type endopeptidase activity

MGI:MGI:1331252
PMID:9990022[2]

IDA: Inferred from Direct Assay

F

From MGI

GO:0004252

serine-type endopeptidase activity

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_446021

F

From MGI

GO:0005783

endoplasmic reticulum

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0256

C

From MGI

GO:0005794

Golgi apparatus

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_446021

C

From MGI

GO:0005795

Golgi stack

MGI:MGI:1331252
PMID:9990022[2]

IDA: Inferred from Direct Assay

C

From MGI

GO:0006508

proteolysis

MGI:MGI:4459044

PANTHER:PTHR10795

P

From MGI

GO:0006629

lipid metabolic process

MGI:MGI:2154012
PMID:11717426[3]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2156485

P

From MGI

GO:0008152

metabolic process

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_446021

P

From MGI

GO:0008202

steroid metabolic process

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0753

P

From MGI

GO:0008203

cholesterol metabolic process

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0153

P

From MGI

GO:0008233

peptidase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0645

F

From MGI

GO:0008236

serine-type peptidase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0720

F

From MGI

GO:0016020

membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0472

C

From MGI

GO:0016021

integral to membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0812

C

From MGI

GO:0016787

hydrolase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0378

F

From MGI

GO:0042990

regulation of transcription factor import into nucleus

MGI:MGI:3611598
PMID:15938716[1]

IDA: Inferred from Direct Assay

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 Nagamori I et al. (2005) Tisp40, a spermatid specific bZip transcription factor, functions by binding to the unfolded protein response element via the Rip pathway. Genes Cells 10: 575-94 PubMed GONUTS page
  2. 2.0 2.1 Seidah NG et al. (1999) Mammalian subtilisin/kexin isozyme SKI-1: A widely expressed proprotein convertase with a unique cleavage specificity and cellular localization. Proc Natl Acad Sci U S A 96: 1321-6 PubMed GONUTS page
  3. Yang J et al. (2001) Decreased lipid synthesis in livers of mice with disrupted Site-1 protease gene. Proc Natl Acad Sci U S A 98: 13607-12 PubMed GONUTS page
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