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MGI:Mavs

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Mavs ( synonyms: IPS-1 )
Protein Name(s) mitochondrial antiviral signaling protein,
External Links
MGI MGI:2444773

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0001934

positive regulation of protein phosphorylation

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q7Z434

P

From MGI

GO:0002218

activation of innate immune response

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q7Z434

P

From MGI

GO:0002230

positive regulation of defense response to virus by host

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q7Z434

P

From MGI

GO:0004871

signal transducer activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q7Z434

F

From MGI

GO:0005515

protein binding

MGI:MGI:3831253
PMID:18849341[1]

IPI: Inferred from Physical Interaction

UniProtKB:Q3UDK1

F

From MGI

GO:0005739

mitochondrion

MGI:MGI:3852644
PMID:18614015[2]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005741

mitochondrial outer membrane

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q7Z434

C

From MGI

GO:0007165

signal transduction

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q7Z434

P

From MGI

GO:0009615

response to virus

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0051

P

From MGI

GO:0016020

membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0472

C

From MGI

GO:0016021

integral to membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0812

C

From MGI

GO:0019901

protein kinase binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q7Z434

F

From MGI

GO:0032727

positive regulation of interferon-alpha production

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q7Z434

P

From MGI

GO:0032728

positive regulation of interferon-beta production

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q7Z434

P

From MGI

GO:0032757

positive regulation of interleukin-8 production

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q7Z434

P

From MGI

GO:0032760

positive regulation of tumor necrosis factor production

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q7Z434

P

From MGI

GO:0033160

positive regulation of protein import into nucleus, translocation

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q7Z434

P

From MGI

GO:0042742

defense response to bacterium

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q7Z434

P

From MGI

GO:0042993

positive regulation of transcription factor import into nucleus

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q7Z434

P

From MGI

GO:0043123

positive regulation of I-kappaB kinase/NF-kappaB cascade

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q7Z434

P

From MGI

GO:0045087

innate immune response

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q7Z434

P

From MGI

GO:0045944

positive regulation of transcription from RNA polymerase II promoter

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q7Z434

P

From MGI

GO:0050700

CARD domain binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q7Z434

F

From MGI

GO:0051091

positive regulation of sequence-specific DNA binding transcription factor activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q7Z434

P

From MGI

GO:0060340

positive regulation of type I interferon-mediated signaling pathway

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q7Z434

P

From MGI

GO:0071360

cellular response to exogenous dsRNA

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q7Z434

P

From MGI

GO:0071651

positive regulation of chemokine (C-C motif) ligand 5 production

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q7Z434

P

From MGI

GO:0071660

positive regulation of IP-10 production

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q7Z434

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Sanada T et al. (2008) FLN29 deficiency reveals its negative regulatory role in the Toll-like receptor (TLR) and retinoic acid-inducible gene I (RIG-I)-like helicase signaling pathway. J Biol Chem 283: 33858-64 PubMed GONUTS page
  2. Pagliarini DJ et al. (2008) A mitochondrial protein compendium elucidates complex I disease biology. Cell 134: 112-23 PubMed GONUTS page
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