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MGI:Marcks

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Marcks ( synonyms: Macs )
Protein Name(s) myristoylated alanine rich protein kinase C substrate,
External Links
MGI MGI:96907

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0003779

actin binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0009

F

From MGI

GO:0005080

protein kinase C binding

MGI:MGI:1326990
PMID:9857183[1]

IPI: Inferred from Physical Interaction

UniProtKB:Q02111

F

From MGI

GO:0005515

protein binding

MGI:MGI:4887342
PMID:12577052[2]

IPI: Inferred from Physical Interaction

UniProtKB:P62158

F

From MGI

GO:0005515

protein binding

MGI:MGI:5285176
PMID:16512683[3]

IPI: Inferred from Physical Interaction

UniProtKB:P62158

F

From MGI

GO:0005516

calmodulin binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0112

F

From MGI

GO:0005516

calmodulin binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR002101

F

From MGI

GO:0005737

cytoplasm

MGI:MGI:3577812
PMID:15766745[4]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005737

cytoplasm

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P30009

C

From MGI

GO:0005813

centrosome

MGI:MGI:3577812
PMID:15766745[4]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005856

cytoskeleton

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0206

C

From MGI

GO:0005938

cell cortex

MGI:MGI:3577812
PMID:15766745[4]

IDA: Inferred from Direct Assay

C

From MGI

GO:0016020

membrane

MGI:MGI:2671687
PMID:12888215[5]

IDA: Inferred from Direct Assay

C

From MGI

GO:0042585

germinal vesicle

MGI:MGI:3577812
PMID:15766745[4]

IDA: Inferred from Direct Assay

C

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Izumi Y et al. (1998) A metalloprotease-disintegrin, MDC9/meltrin-gamma/ADAM9 and PKCdelta are involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor. EMBO J 17: 7260-72 PubMed GONUTS page
  2. Yamauchi E et al. (2003) Crystal structure of a MARCKS peptide containing the calmodulin-binding domain in complex with Ca2+-calmodulin. Nat Struct Biol 10: 226-31 PubMed GONUTS page
  3. Berggård T et al. (2006) 140 mouse brain proteins identified by Ca2+-calmodulin affinity chromatography and tandem mass spectrometry. J Proteome Res 5: 669-87 PubMed GONUTS page
  4. 4.0 4.1 4.2 4.3 Michaut MA et al. (2005) Phosphorylated MARCKS: a novel centrosome component that also defines a peripheral subdomain of the cortical actin cap in mouse eggs. Dev Biol 280: 26-37 PubMed GONUTS page
  5. Scarlett CO & Blackshear PJ (2003) Neuroanatomical development in the absence of PKC phosphorylation of the myristoylated alanine-rich C-kinase substrate (MARCKS) protein. Brain Res Dev Brain Res 144: 25-42 PubMed GONUTS page
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