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MGI:Mapk8ip3
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Mapk8ip3 ( synonyms: c-Jun NH2-terminal kinase (JNK)/stress-activated protein kinase-associated protein 1, D17Wsu15e, Jip3, JNK-interacting protein 3, JSAP1, JSAP1a, JSAP1b, JSAP1c, JSAP1d, JUN/SAPK-associated protein 1, sunday driver 2, Syd2 ) | |
| Protein Name(s) | mitogen-activated protein kinase 8 interacting protein 3, | |
| External Links | ||
| MGI | MGI:1353598 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000139 |
Golgi membrane |
MGI:MGI:2148806 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0001701 |
in utero embryonic development |
MGI:MGI:3796918 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3527900 |
P |
From MGI |
||
| GO:0005078 |
MAP-kinase scaffold activity |
MGI:MGI:1352260 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005078 |
MAP-kinase scaffold activity |
MGI:MGI:1890011 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:2148806 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005625 |
soluble fraction |
MGI:MGI:3629289 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:1352260 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:1890011 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:3575843 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005790 |
smooth endoplasmic reticulum |
MGI:MGI:3629289 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005794 |
Golgi apparatus |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0333 |
C |
From MGI |
||
| GO:0005886 |
plasma membrane |
MGI:MGI:3629289 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0007254 |
JNK cascade |
MGI:MGI:1352260 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0007257 |
activation of JUN kinase activity |
MGI:MGI:3575843 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0007411 |
axon guidance |
MGI:MGI:3527288 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3527900 |
P |
From MGI |
||
| GO:0007585 |
respiratory gaseous exchange |
MGI:MGI:2673021 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3053053 |
P |
From MGI |
||
| GO:0008104 |
protein localization |
MGI:MGI:3527288 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3527900 |
P |
From MGI |
||
| GO:0008432 |
JUN kinase binding |
MGI:MGI:1890011 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0009791 |
post-embryonic development |
MGI:MGI:3796918 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3527900 |
P |
From MGI |
||
| GO:0009967 |
positive regulation of signal transduction |
MGI:MGI:1352260 |
IPI: Inferred from Physical Interaction |
P |
From MGI |
|||
| GO:0009967 |
positive regulation of signal transduction |
MGI:MGI:1890011 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0010468 |
regulation of gene expression |
MGI:MGI:3796918 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0016192 |
vesicle-mediated transport |
MGI:MGI:2148806 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0016301 |
kinase activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0418 |
F |
From MGI |
||
| GO:0016310 |
phosphorylation |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0418 |
P |
From MGI |
||
| GO:0019894 |
kinesin binding |
MGI:MGI:1352260 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0019901 |
protein kinase binding |
MGI:MGI:1352260 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0030425 |
dendrite |
MGI:MGI:3629289 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0030673 |
axolemma |
MGI:MGI:3629289 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0030900 |
forebrain development |
MGI:MGI:2673021 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3053053 |
P |
From MGI |
||
| GO:0030900 |
forebrain development |
MGI:MGI:3527288 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3527900 |
P |
From MGI |
||
| GO:0031410 |
cytoplasmic vesicle |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0968 |
C |
From MGI |
||
| GO:0031434 |
mitogen-activated protein kinase kinase binding |
MGI:MGI:1890011 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0031434 |
mitogen-activated protein kinase kinase binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_001094143 |
F |
From MGI |
||
| GO:0031435 |
mitogen-activated protein kinase kinase kinase binding |
MGI:MGI:1890011 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0042995 |
cell projection |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0966 |
C |
From MGI |
||
| GO:0043005 |
neuron projection |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_001094143 |
C |
From MGI |
||
| GO:0043507 |
positive regulation of JUN kinase activity |
MGI:MGI:1890011 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0045666 |
positive regulation of neuron differentiation |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_001094143 |
P |
From MGI |
||
| GO:0046328 |
regulation of JNK cascade |
MGI:MGI:1352260 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0048286 |
lung alveolus development |
MGI:MGI:3796918 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3527900 |
P |
From MGI |
||
| GO:0060425 |
lung morphogenesis |
MGI:MGI:3796918 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3527900 |
P |
From MGI |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 Bowman AB et al. (2000) Kinesin-dependent axonal transport is mediated by the sunday driver (SYD) protein. Cell 103: 583-94 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 2.4 Ha HY et al. (2008) Morphogenetic lung defects of JSAP1-deficient embryos proceeds via the disruptions of the normal expressions of cytoskeletal and chaperone proteins. Proteomics 8: 1071-80 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 3.4 3.5 3.6 Kelkar N et al. (2000) Interaction of a mitogen-activated protein kinase signaling module with the neuronal protein JIP3. Mol Cell Biol 20: 1030-43 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 4.3 4.4 4.5 4.6 Ito M et al. (1999) JSAP1, a novel jun N-terminal protein kinase (JNK)-binding protein that functions as a Scaffold factor in the JNK signaling pathway. Mol Cell Biol 19: 7539-48 PubMed GONUTS page
- ↑ 5.0 5.1 5.2 5.3 5.4 Miura E et al. (2006) Expression and distribution of JNK/SAPK-associated scaffold protein JSAP1 in developing and adult mouse brain. J Neurochem 97: 1431-46 PubMed GONUTS page
- ↑ 6.0 6.1 Kelkar N et al. (2005) Role of the JIP4 scaffold protein in the regulation of mitogen-activated protein kinase signaling pathways. Mol Cell Biol 25: 2733-43 PubMed GONUTS page
- ↑ 7.0 7.1 7.2 Ha HY et al. (2005) The axon guidance defect of the telencephalic commissures of the JSAP1-deficient brain was partially rescued by the transgenic expression of JIP1. Dev Biol 277: 184-99 PubMed GONUTS page
- ↑ 8.0 8.1 Kelkar N et al. (2003) Morphogenesis of the telencephalic commissure requires scaffold protein JNK-interacting protein 3 (JIP3). Proc Natl Acad Sci U S A 100: 9843-8 PubMed GONUTS page
