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MGI:Map3k14

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Map3k14 ( synonyms: Nik )
Protein Name(s) mitogen-activated protein kinase kinase kinase 14,
External Links
MGI MGI:1858204

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000166

nucleotide binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0547

F

From MGI

GO:0000186

activation of MAPKK activity

MGI:MGI:2152096

IEA: Inferred from Electronic Annotation

EC:2.7.11.25

P

From MGI

GO:0004672

protein kinase activity

MGI:MGI:3040582
PMID:15001576[1]

ISO: Inferred from Sequence Orthology

UniProtKB:Q99558

F

From MGI

GO:0004672

protein kinase activity

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_001101771

F

From MGI

GO:0004674

protein serine/threonine kinase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0723

F

From MGI

GO:0004674

protein serine/threonine kinase activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR008271

F

From MGI

GO:0004704

NF-kappaB-inducing kinase activity

MGI:MGI:1931349
PMID:11239468[2]

IDA: Inferred from Direct Assay

F

From MGI

GO:0004709

MAP kinase kinase kinase activity

MGI:MGI:2152096

IEA: Inferred from Electronic Annotation

EC:2.7.11.25

F

From MGI

GO:0005515

protein binding

MGI:MGI:1931349
PMID:11239468[2]

IPI: Inferred from Physical Interaction

UniProtKB:Q00653

F

From MGI

GO:0005524

ATP binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0067

F

From MGI

GO:0005524

ATP binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR000719
InterPro:IPR017441

F

From MGI

GO:0005622

intracellular

MGI:MGI:1931349
PMID:11239468[2]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005634

nucleus

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q99558

C

From MGI

GO:0005737

cytoplasm

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q99558

C

From MGI

GO:0006468

protein phosphorylation

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0723

P

From MGI

GO:0006468

protein phosphorylation

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR008271

P

From MGI

GO:0006468

protein phosphorylation

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_001101771

P

From MGI

GO:0006468

protein phosphorylation

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q99558

P

From MGI

GO:0006955

immune response

MGI:MGI:1931349
PMID:11239468[2]

IDA: Inferred from Direct Assay

P

From MGI

GO:0007249

I-kappaB kinase/NF-kappaB cascade

MGI:MGI:1931349
PMID:11239468[2]

IDA: Inferred from Direct Assay

P

From MGI

GO:0016301

kinase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0418

F

From MGI

GO:0016310

phosphorylation

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0418

P

From MGI

GO:0016740

transferase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0808

F

From MGI

GO:0016772

transferase activity, transferring phosphorus-containing groups

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR011009

F

From MGI

GO:0038061

NIK/NF-kappaB cascade

MGI:MGI:1931349
PMID:11239468[2]

IDA: Inferred from Direct Assay

P

From MGI

GO:0043123

positive regulation of I-kappaB kinase/NF-kappaB cascade

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q99558

P

From MGI

GO:0043231

intracellular membrane-bounded organelle

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q99558

C

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Xu LG et al. (2004) TRAF7 potentiates MEKK3-induced AP1 and CHOP activation and induces apoptosis. J Biol Chem 279: 17278-82 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 2.5 Xiao G et al. (2001) NF-kappaB-inducing kinase regulates the processing of NF-kappaB2 p100. Mol Cell 7: 401-9 PubMed GONUTS page
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