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MGI:Maf
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Maf ( synonyms: c-maf ) | |
| Protein Name(s) | avian musculoaponeurotic fibrosarcoma (v-maf) AS42 oncogene homolog, | |
| External Links | ||
| MGI | MGI:96909 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000122 |
negative regulation of transcription from RNA polymerase II promoter |
MGI:MGI:4354418 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2148637 |
P |
From MGI |
||
| GO:0000981 |
sequence-specific DNA binding RNA polymerase II transcription factor activity |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0001816 |
cytokine production |
MGI:MGI:3575325 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0002088 |
lens development in camera-type eye |
MGI:MGI:1340085 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2148637 |
P |
From MGI |
||
| GO:0002088 |
lens development in camera-type eye |
MGI:MGI:1350584 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2148635 |
P |
From MGI |
||
| GO:0002088 |
lens development in camera-type eye |
MGI:MGI:3760711 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2148636 |
P |
From MGI |
||
| GO:0003677 |
DNA binding |
MGI:MGI:2447911 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0003690 |
double-stranded DNA binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0003700 |
sequence-specific DNA binding transcription factor activity |
MGI:MGI:3760711 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:2447911 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:3051732 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:3051732 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0006351 |
transcription, DNA-dependent |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0804 |
P |
From MGI |
||
| GO:0006355 |
regulation of transcription, DNA-dependent |
MGI:MGI:2384335 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2148636 |
P |
From MGI |
||
| GO:0006366 |
transcription from RNA polymerase II promoter |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0010628 |
positive regulation of gene expression |
MGI:MGI:5004747 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0032330 |
regulation of chondrocyte differentiation |
MGI:MGI:2676505 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2148636 |
P |
From MGI |
||
| GO:0042803 |
protein homodimerization activity |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0043565 |
sequence-specific DNA binding |
MGI:MGI:1350584 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0045944 |
positive regulation of transcription from RNA polymerase II promoter |
MGI:MGI:1350584 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2148635 |
P |
From MGI |
||
| GO:0045944 |
positive regulation of transcription from RNA polymerase II promoter |
MGI:MGI:2447911 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0045944 |
positive regulation of transcription from RNA polymerase II promoter |
MGI:MGI:3760711 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0045944 |
positive regulation of transcription from RNA polymerase II promoter |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0046982 |
protein heterodimerization activity |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0048468 |
cell development |
MGI:MGI:1350584 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2148635 |
P |
From MGI |
||
| GO:0048839 |
inner ear development |
MGI:MGI:5140238 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0070306 |
lens fiber cell differentiation |
MGI:MGI:1340085 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2148637 |
P |
From MGI |
||
| GO:0070306 |
lens fiber cell differentiation |
MGI:MGI:3760711 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2148636 |
P |
From MGI |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Maeda A et al. (2009) Transcription factor GATA-3 is essential for lens development. Dev Dyn 238: 2280-91 PubMed GONUTS page
- ↑ Bettelli E et al. (2005) Foxp3 interacts with nuclear factor of activated T cells and NF-kappa B to repress cytokine gene expression and effector functions of T helper cells. Proc Natl Acad Sci U S A 102: 5138-43 PubMed GONUTS page
- ↑ 3.0 3.1 Kawauchi S et al. (1999) Regulation of lens fiber cell differentiation by transcription factor c-Maf. J Biol Chem 274: 19254-60 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 4.3 Ring BZ et al. (2000) Regulation of mouse lens fiber cell development and differentiation by the Maf gene. Development 127: 307-17 PubMed GONUTS page
- ↑ 5.0 5.1 5.2 5.3 DePianto DJ et al. (2003) Analysis of non-crystallin lens fiber cell gene expression in c-Maf -/- mice. Mol Vis 9: 288-94 PubMed GONUTS page
- ↑ 6.0 6.1 6.2 Huang W et al. (2002) A new long form of c-Maf cooperates with Sox9 to activate the type II collagen gene. J Biol Chem 277: 50668-75 PubMed GONUTS page
- ↑ 7.0 7.1 Imaki J et al. (2004) Developmental contribution of c-maf in the kidney: distribution and developmental study of c-maf mRNA in normal mice kidney and histological study of c-maf knockout mice kidney and liver. Biochem Biophys Res Commun 320: 1323-7 PubMed GONUTS page
- ↑ Kim JI et al. (1999) The transcription factor c-Maf controls the production of interleukin-4 but not other Th2 cytokines. Immunity 10: 745-51 PubMed GONUTS page
- ↑ Motomura Y et al. (2011) The transcription factor E4BP4 regulates the production of IL-10 and IL-13 in CD4+ T cells. Nat Immunol 12: 450-9 PubMed GONUTS page
- ↑ MacLean HE et al. (2003) Absence of transcription factor c-maf causes abnormal terminal differentiation of hypertrophic chondrocytes during endochondral bone development. Dev Biol 262: 51-63 PubMed GONUTS page
- ↑ Lu CC et al. (2011) Developmental profiling of spiral ganglion neurons reveals insights into auditory circuit assembly. J Neurosci 31: 10903-18 PubMed GONUTS page
