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MGI:Mael

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Mael
Protein Name(s) maelstrom homolog (Drosophila),
External Links
MGI MGI:2138453

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000122

negative regulation of transcription from RNA polymerase II promoter

MGI:MGI:3813746
PMID:18694567[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3795667

P

From MGI

GO:0000785

chromatin

MGI:MGI:3655410
PMID:16787967[2]

IDA: Inferred from Direct Assay

C

From MGI

GO:0000902

cell morphogenesis

MGI:MGI:3813746
PMID:18694567[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3795667

P

From MGI

GO:0001741

XY body

MGI:MGI:3655410
PMID:16787967[2]

IDA: Inferred from Direct Assay

C

From MGI

GO:0003677

DNA binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0238

F

From MGI

GO:0005515

protein binding

MGI:MGI:3655410
PMID:16787967[2]

IPI: Inferred from Physical Interaction

UniProtKB:Q9Z0H3
UniProtKB:Q62141
UniProtKB:P69566
UniProtKB:Q8K1H1
UniProtKB:Q99MV1
UniProtKB:Q61496
UniProtKB:Q9JMB7
UniProtKB:Q8CDG1

F

From MGI

GO:0005634

nucleus

MGI:MGI:3655410
PMID:16787967[2]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005634

nucleus

MGI:MGI:3813746
PMID:18694567[1]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005634

nucleus

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q96JY0

C

From MGI

GO:0005737

cytoplasm

MGI:MGI:3655410
PMID:16787967[2]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005737

cytoplasm

MGI:MGI:3813746
PMID:18694567[1]

IDA: Inferred from Direct Assay

C

From MGI

GO:0006974

response to DNA damage stimulus

MGI:MGI:3813746
PMID:18694567[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3795667

P

From MGI

GO:0007126

meiosis

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0469

P

From MGI

GO:0007128

meiotic prophase I

MGI:MGI:3813746
PMID:18694567[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3795667

P

From MGI

GO:0007129

synapsis

MGI:MGI:3813746
PMID:18694567[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3795667

P

From MGI

GO:0007140

male meiosis

MGI:MGI:3813746
PMID:18694567[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3795667

P

From MGI

GO:0007275

multicellular organismal development

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0217

P

From MGI

GO:0007283

spermatogenesis

MGI:MGI:3813746
PMID:18694567[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3795667

P

From MGI

GO:0009566

fertilization

MGI:MGI:3813746
PMID:18694567[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3795667

P

From MGI

GO:0010629

negative regulation of gene expression

MGI:MGI:3813746
PMID:18694567[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3795667

P

From MGI

GO:0016585

chromatin remodeling complex

MGI:MGI:3655410
PMID:16787967[2]

IDA: Inferred from Direct Assay

C

From MGI

GO:0030154

cell differentiation

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0221

P

From MGI

GO:0030849

autosome

MGI:MGI:3655410
PMID:16787967[2]

IDA: Inferred from Direct Assay

C

From MGI

GO:0031047

gene silencing by RNA

MGI:MGI:3813746
PMID:18694567[1]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0033391

chromatoid body

MGI:MGI:3655410
PMID:16787967[2]

IDA: Inferred from Direct Assay

C

From MGI

GO:0034587

piRNA metabolic process

MGI:MGI:3813746
PMID:18694567[1]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0034587

piRNA metabolic process

MGI:MGI:4417983
PMID:20011505[3]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0043046

DNA methylation involved in gamete generation

MGI:MGI:4417983
PMID:20011505[3]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0043066

negative regulation of apoptotic process

MGI:MGI:3813746
PMID:18694567[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3795667

P

From MGI

GO:0043186

P granule

MGI:MGI:3655410
PMID:16787967[2]

IDA: Inferred from Direct Assay

C

From MGI

GO:0043186

P granule

MGI:MGI:3813746
PMID:18694567[1]

IDA: Inferred from Direct Assay

C

From MGI

GO:0043231

intracellular membrane-bounded organelle

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q96JY0

C

From MGI

GO:0046620

regulation of organ growth

MGI:MGI:3813746
PMID:18694567[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3795667

P

From MGI

GO:0048471

perinuclear region of cytoplasm

MGI:MGI:3813746
PMID:18694567[1]

IDA: Inferred from Direct Assay

C

From MGI

GO:0071547

piP-body

MGI:MGI:4417983
PMID:20011505[3]

IDA: Inferred from Direct Assay

C

From MGI

NOT

GO:0001741

XY body

MGI:MGI:3813746
PMID:18694567[1]

IDA: Inferred from Direct Assay

C

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.00 1.01 1.02 1.03 1.04 1.05 1.06 1.07 1.08 1.09 1.10 1.11 1.12 1.13 1.14 1.15 1.16 1.17 Soper SF et al. (2008) Mouse maelstrom, a component of nuage, is essential for spermatogenesis and transposon repression in meiosis. Dev Cell 15: 285-97 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 2.5 2.6 2.7 2.8 Costa Y et al. (2006) Mouse MAELSTROM: the link between meiotic silencing of unsynapsed chromatin and microRNA pathway? Hum Mol Genet 15: 2324-34 PubMed GONUTS page
  3. 3.0 3.1 3.2 Aravin AA et al. (2009) Cytoplasmic compartmentalization of the fetal piRNA pathway in mice. PLoS Genet 5: e1000764 PubMed GONUTS page
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