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MGI:Ltb

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Ltb ( synonyms: LTbeta, lymphotoxin beta, p33, Tnfc, Tnfsf3 )
Protein Name(s) lymphotoxin B,
External Links
MGI MGI:104796

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0005125

cytokine activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0202

F

From MGI

GO:0005164

tumor necrosis factor receptor binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR006052
InterPro:IPR006053
InterPro:IPR002961

F

From MGI

GO:0005615

extracellular space

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0202

C

From MGI

GO:0005886

plasma membrane

MGI:MGI:1095831
PMID:9256477[1]

TAS: Traceable Author Statement

C

From MGI

GO:0005886

plasma membrane

MGI:MGI:87095
PMID:9133428[2]

TAS: Traceable Author Statement

C

From MGI

GO:0006955

immune response

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR006052
InterPro:IPR006053
InterPro:IPR002961

P

From MGI

GO:0010467

gene expression

MGI:MGI:3770480
PMID:17673451[3]

IMP: Inferred from Mutant Phenotype

MGI:MGI:1860970

P

From MGI

GO:0016020

membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0472

C

From MGI

GO:0016020

membrane

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR006052
InterPro:IPR006053
InterPro:IPR002961

C

From MGI

GO:0016021

integral to membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0812

C

From MGI

GO:0043588

skin development

MGI:MGI:3770480
PMID:17673451[3]

IMP: Inferred from Mutant Phenotype

MGI:MGI:1860970

P

From MGI

GO:0045084

positive regulation of interleukin-12 biosynthetic process

MGI:MGI:3773766
PMID:17982081[4]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0048535

lymph node development

MGI:MGI:1095831
PMID:9256477[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:1860970

P

From MGI

GO:0048535

lymph node development

MGI:MGI:87095
PMID:9133428[2]

IMP: Inferred from Mutant Phenotype

MGI:MGI:1860955

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 Alimzhanov MB et al. (1997) Abnormal development of secondary lymphoid tissues in lymphotoxin beta-deficient mice. Proc Natl Acad Sci U S A 94: 9302-7 PubMed GONUTS page
  2. 2.0 2.1 Koni PA et al. (1997) Distinct roles in lymphoid organogenesis for lymphotoxins alpha and beta revealed in lymphotoxin beta-deficient mice. Immunity 6: 491-500 PubMed GONUTS page
  3. 3.0 3.1 Cui CY et al. (2007) Lymphotoxin-beta regulates periderm differentiation during embryonic skin development. Hum Mol Genet 16: 2583-90 PubMed GONUTS page
  4. Xu G et al. (2007) LIGHT Is critical for IL-12 production by dendritic cells, optimal CD4+ Th1 cell response, and resistance to Leishmania major. J Immunol 179: 6901-9 PubMed GONUTS page
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