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MGI:Lingo1
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Lingo1 ( synonyms: LERN1, LINGO-1, Lrrn6a, UNQ201 ) | |
| Protein Name(s) | leucine rich repeat and Ig domain containing 1, | |
| External Links | ||
| MGI | MGI:1915522 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0005154 |
epidermal growth factor receptor binding |
MGI:MGI:3722980 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3829123 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005622 |
intracellular |
MGI:MGI:3722980 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005886 |
plasma membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-1003 |
C |
From MGI |
||
| GO:0016020 |
membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0472 |
C |
From MGI |
||
| GO:0016021 |
integral to membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0812 |
C |
From MGI |
||
| GO:0021954 |
central nervous system neuron development |
MGI:MGI:3722980 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0021954 |
central nervous system neuron development |
MGI:MGI:3722980 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3623893 |
P |
From MGI |
||
| GO:0031175 |
neuron projection development |
MGI:MGI:3722980 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0043491 |
protein kinase B signaling cascade |
MGI:MGI:3722980 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0048715 |
negative regulation of oligodendrocyte differentiation |
MGI:MGI:3581086 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 Inoue H et al. (2007) Inhibition of the leucine-rich repeat protein LINGO-1 enhances survival, structure, and function of dopaminergic neurons in Parkinson's disease models. Proc Natl Acad Sci U S A 104: 14430-5 PubMed GONUTS page
- ↑ Bai Y et al. (2008) The in vivo brain interactome of the amyloid precursor protein. Mol Cell Proteomics 7: 15-34 PubMed GONUTS page
- ↑ Mi S et al. (2005) LINGO-1 negatively regulates myelination by oligodendrocytes. Nat Neurosci 8: 745-51 PubMed GONUTS page