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MGI:Lhcgr
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Lhcgr ( synonyms: Gpcr19-rs1, LH-R, Lhr ) | |
| Protein Name(s) | luteinizing hormone/choriogonadotropin receptor, | |
| External Links | ||
| MGI | MGI:96783 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0001541 |
ovarian follicle development |
MGI:MGI:1929316 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2181999 |
P |
From MGI |
||
| GO:0004871 |
signal transducer activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0807 |
F |
From MGI |
||
| GO:0004872 |
receptor activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0675 |
F |
From MGI |
||
| GO:0004930 |
G-protein coupled receptor activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0297 |
F |
From MGI |
||
| GO:0004964 |
luteinizing hormone receptor activity |
MGI:MGI:50386 |
TAS: Traceable Author Statement |
F |
From MGI |
|||
| GO:0005615 |
extracellular space |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005764 |
lysosome |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005768 |
endosome |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005783 |
endoplasmic reticulum |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005886 |
plasma membrane |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005887 |
integral to plasma membrane |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0006622 |
protein targeting to lysosome |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0007165 |
signal transduction |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0807 |
P |
From MGI |
||
| GO:0007186 |
G-protein coupled receptor signaling pathway |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0297 |
P |
From MGI |
||
| GO:0007186 |
G-protein coupled receptor signaling pathway |
MGI:MGI:1929316 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2181999 |
P |
From MGI |
||
| GO:0007186 |
G-protein coupled receptor signaling pathway |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0007188 |
G-protein signaling, coupled to cAMP nucleotide second messenger |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0007190 |
activation of adenylate cyclase activity |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0007200 |
activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0007283 |
spermatogenesis |
MGI:MGI:1929316 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2181999 |
P |
From MGI |
||
| GO:0008528 |
G-protein coupled peptide receptor activity |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0008584 |
male gonad development |
MGI:MGI:1929316 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2181999 |
P |
From MGI |
||
| GO:0008585 |
female gonad development |
MGI:MGI:1929316 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2181999 |
P |
From MGI |
||
| GO:0009755 |
hormone-mediated signaling pathway |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0010524 |
positive regulation of calcium ion transport into cytosol |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0016020 |
membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0472 |
C |
From MGI |
||
| GO:0016021 |
integral to membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0812 |
C |
From MGI |
||
| GO:0016021 |
integral to membrane |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
C |
From MGI |
|||
| GO:0016500 |
protein-hormone receptor activity |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0017046 |
peptide hormone binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0022602 |
ovulation cycle process |
MGI:MGI:1929316 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2181999 |
P |
From MGI |
||
| GO:0031233 |
intrinsic to external side of plasma membrane |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0035472 |
choriogonadotropin hormone receptor activity |
MGI:MGI:1929316 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2181999 |
F |
From MGI |
||
| GO:0042700 |
luteinizing hormone signaling pathway |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0042802 |
identical protein binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0042803 |
protein homodimerization activity |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0043235 |
receptor complex |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0046544 |
development of secondary male sexual characteristics |
MGI:MGI:1929316 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2181999 |
P |
From MGI |
||
| GO:0046886 |
positive regulation of hormone biosynthetic process |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0050482 |
arachidonic acid secretion |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0050850 |
positive regulation of calcium-mediated signaling |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0051117 |
ATPase binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0051281 |
positive regulation of release of sequestered calcium ion into cytosol |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0060065 |
uterus development |
MGI:MGI:1929316 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2181999 |
P |
From MGI |
||
| GO:0061039 |
ovum-producing ovary development |
MGI:MGI:1929316 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2181999 |
P |
From MGI |
||
| GO:0061039 |
ovum-producing ovary development |
MGI:MGI:3583390 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2181999 |
P |
From MGI |
||
| GO:0072520 |
seminiferous tubule development |
MGI:MGI:1929316 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2181999 |
P |
From MGI |
||
| GO:0090030 |
regulation of steroid hormone biosynthetic process |
MGI:MGI:1929316 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2181999 |
P |
From MGI |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.00 1.01 1.02 1.03 1.04 1.05 1.06 1.07 1.08 1.09 1.10 1.11 Zhang FP et al. (2001) Normal prenatal but arrested postnatal sexual development of luteinizing hormone receptor knockout (LuRKO) mice. Mol Endocrinol 15: 172-83 PubMed GONUTS page
- ↑ Gudermann T et al. (1992) Evidence for dual coupling of the murine luteinizing hormone receptor to adenylyl cyclase and phosphoinositide breakdown and Ca2+ mobilization. Studies with the cloned murine luteinizing hormone receptor expressed in L cells. J Biol Chem 267: 4479-88 PubMed GONUTS page
- ↑ Pakarainen T et al. (2005) Fertility in luteinizing hormone receptor-knockout mice after wild-type ovary transplantation demonstrates redundancy of extragonadal luteinizing hormone action. J Clin Invest 115: 1862-8 PubMed GONUTS page
