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MGI:Ldlrap1
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Ldlrap1 ( synonyms: Arh, Arh1 ) | |
| Protein Name(s) | low density lipoprotein receptor adaptor protein 1, | |
| External Links | ||
| MGI | MGI:2140175 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0001540 |
beta-amyloid binding |
MGI:MGI:3762243 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0001540 |
beta-amyloid binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0001784 |
phosphotyrosine binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0005102 |
receptor binding |
MGI:MGI:2445253 |
ISA: Inferred from Sequence Alignment |
EMBL:AL117654 |
F |
From MGI |
||
| GO:0005515 |
protein binding |
MGI:MGI:2669061 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3762243 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005546 |
phosphatidylinositol-4,5-bisphosphate binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:3762243 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005769 |
early endosome |
MGI:MGI:2669061 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005769 |
early endosome |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005829 |
cytosol |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005883 |
neurofilament |
MGI:MGI:3762243 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0006629 |
lipid metabolic process |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0443 |
P |
From MGI |
||
| GO:0006897 |
endocytosis |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0254 |
P |
From MGI |
||
| GO:0006898 |
receptor-mediated endocytosis |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0008202 |
steroid metabolic process |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0753 |
P |
From MGI |
||
| GO:0008203 |
cholesterol metabolic process |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0153 |
P |
From MGI |
||
| GO:0009898 |
internal side of plasma membrane |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0009925 |
basal plasma membrane |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0009967 |
positive regulation of signal transduction |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0030159 |
receptor signaling complex scaffold activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0030276 |
clathrin binding |
MGI:MGI:2445253 |
ISA: Inferred from Sequence Alignment |
EMBL:AL117654 |
F |
From MGI |
||
| GO:0030276 |
clathrin binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0030424 |
axon |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_001102741 |
C |
From MGI |
||
| GO:0031623 |
receptor internalization |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0035591 |
signaling adaptor activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0035612 |
AP-2 adaptor complex binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0035615 |
clathrin adaptor activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0042632 |
cholesterol homeostasis |
MGI:MGI:2669061 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2670480 |
P |
From MGI |
||
| GO:0042632 |
cholesterol homeostasis |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0042982 |
amyloid precursor protein metabolic process |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0043393 |
regulation of protein binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0048260 |
positive regulation of receptor-mediated endocytosis |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0050750 |
low-density lipoprotein particle receptor binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0055037 |
recycling endosome |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0090003 |
regulation of establishment of protein localization in plasma membrane |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0090118 |
receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 Mameza MG et al. (2007) Characterization of the adaptor protein ARH expression in the brain and ARH molecular interactions. J Neurochem 103: 927-41 PubMed GONUTS page
- ↑ 2.0 2.1 He G et al. (2002) ARH is a modular adaptor protein that interacts with the LDL receptor, clathrin, and AP-2. J Biol Chem 277: 44044-9 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 Jones C et al. (2003) Normal sorting but defective endocytosis of the low density lipoprotein receptor in mice with autosomal recessive hypercholesterolemia. J Biol Chem 278: 29024-30 PubMed GONUTS page
