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MGI:Ldha
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Ldha ( synonyms: l7R2, lactate dehydrogenase-A, Ldh-1, LDH-A, Ldh1 ) | |
| Protein Name(s) | lactate dehydrogenase A, | |
| External Links | ||
| MGI | MGI:96759 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000166 |
nucleotide binding |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0003824 |
catalytic activity |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0004457 |
lactate dehydrogenase activity |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0004459 |
L-lactate dehydrogenase activity |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0004459 |
L-lactate dehydrogenase activity |
MGI:MGI:55148 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0004459 |
L-lactate dehydrogenase activity |
MGI:MGI:63598 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3776263 |
F |
From MGI |
||
| GO:0005515 |
protein binding |
MGI:MGI:3693398 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005625 |
soluble fraction |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0963 |
C |
From MGI |
||
| GO:0005737 |
cytoplasm |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
C |
From MGI |
|||
| GO:0005739 |
mitochondrion |
MGI:MGI:3852644 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005829 |
cytosol |
MGI:MGI:2178871 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005975 |
carbohydrate metabolic process |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0006089 |
lactate metabolic process |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0006096 |
glycolysis |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0324 |
P |
From MGI |
||
| GO:0006096 |
glycolysis |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0016491 |
oxidoreductase activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0560 |
F |
From MGI |
||
| GO:0016491 |
oxidoreductase activity |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0016616 |
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0019674 |
NAD metabolic process |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0019861 |
flagellum |
MGI:MGI:3654822 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0019900 |
kinase binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0031668 |
cellular response to extracellular stimulus |
MGI:MGI:1335904 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0042802 |
identical protein binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0043065 |
positive regulation of apoptotic process |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0044262 |
cellular carbohydrate metabolic process |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0051287 |
NAD binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Stallings RL & Siciliano MJ (1981) Confirmational, provisional, and/or regional assignment of 15 enzyme loci onto Chinese hamster autosomes 1, 2, and 7. Somatic Cell Genet 7: 683-98 PubMed GONUTS page
- ↑ Charles DJ & Pretsch W (1987) Linear dose-response relationship of erythrocyte enzyme-activity mutations in offspring of ethylnitrosourea-treated mice. Mutat Res 176: 81-91 PubMed GONUTS page
- ↑ Pioli PA et al. (2002) Lactate dehydrogenase is an AU-rich element-binding protein that directly interacts with AUF1. J Biol Chem 277: 35738-45 PubMed GONUTS page
- ↑ Pagliarini DJ et al. (2008) A mitochondrial protein compendium elucidates complex I disease biology. Cell 134: 112-23 PubMed GONUTS page
- ↑ Putcha GV et al. (2002) Intrinsic and extrinsic pathway signaling during neuronal apoptosis: lessons from the analysis of mutant mice. J Cell Biol 157: 441-53 PubMed GONUTS page
- ↑ Krisfalusi M et al. (2006) Multiple glycolytic enzymes are tightly bound to the fibrous sheath of mouse spermatozoa. Biol Reprod 75: 270-8 PubMed GONUTS page
- ↑ Leimeister C et al. (1999) Screen for genes regulated during early kidney morphogenesis. Dev Genet 24: 273-83 PubMed GONUTS page