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MGI:Lcat
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Lcat ( synonyms: D8Wsu61e ) | |
| Protein Name(s) | lecithin cholesterol acyltransferase, | |
| External Links | ||
| MGI | MGI:96755 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0004607 |
phosphatidylcholine-sterol O-acyltransferase activity |
MGI:MGI:1096057 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0004607 |
phosphatidylcholine-sterol O-acyltransferase activity |
MGI:MGI:1352038 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0004607 |
phosphatidylcholine-sterol O-acyltransferase activity |
MGI:MGI:1352057 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0004607 |
phosphatidylcholine-sterol O-acyltransferase activity |
MGI:MGI:3616112 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0004607 |
phosphatidylcholine-sterol O-acyltransferase activity |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0004607 |
phosphatidylcholine-sterol O-acyltransferase activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0004623 |
phospholipase A2 activity |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0005576 |
extracellular region |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0964 |
C |
From MGI |
||
| GO:0005615 |
extracellular space |
MGI:MGI:1352038 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005615 |
extracellular space |
MGI:MGI:1352057 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005615 |
extracellular space |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0006629 |
lipid metabolic process |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0443 |
P |
From MGI |
||
| GO:0006629 |
lipid metabolic process |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0006644 |
phospholipid metabolic process |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0006656 |
phosphatidylcholine biosynthetic process |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0008202 |
steroid metabolic process |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0753 |
P |
From MGI |
||
| GO:0008203 |
cholesterol metabolic process |
MGI:MGI:1096057 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0008203 |
cholesterol metabolic process |
MGI:MGI:1352038 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0008203 |
cholesterol metabolic process |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0008203 |
cholesterol metabolic process |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0008374 |
O-acyltransferase activity |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0016740 |
transferase activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0808 |
F |
From MGI |
||
| GO:0016746 |
transferase activity, transferring acyl groups |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0012 |
F |
From MGI |
||
| GO:0030301 |
cholesterol transport |
MGI:MGI:1352038 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0034186 |
apolipoprotein A-I binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0034364 |
high-density lipoprotein particle |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0034372 |
very-low-density lipoprotein particle remodeling |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0034375 |
high-density lipoprotein particle remodeling |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0034435 |
cholesterol esterification |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0042157 |
lipoprotein metabolic process |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0042158 |
lipoprotein biosynthetic process |
MGI:MGI:3616112 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0042632 |
cholesterol homeostasis |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0043691 |
reverse cholesterol transport |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0046688 |
response to copper ion |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0051384 |
response to glucocorticoid stimulus |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0090107 |
regulation of high-density lipoprotein particle assembly |
MGI:MGI:3848791 |
IDA: Inferred from Direct Assay |
P |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Webb NR et al. (1997) Adenoviral vector-mediated overexpression of serum amyloid A in apoA-I-deficient mice. J Lipid Res 38: 1583-90 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 Fournier N et al. (1999) Fractional efflux and net change in cellular cholesterol content mediated by sera from mice expressing both human apolipoprotein AI and human lecithin:cholesterol acyltransferase genes. Atherosclerosis 147: 227-35 PubMed GONUTS page
- ↑ 3.0 3.1 She M et al. (1999) Inhibition of intimal lipid deposition in human apolipoprotein A1 transgenic mice. Clin Exp Pharmacol Physiol 26: 833-4 PubMed GONUTS page
- ↑ 4.0 4.1 Chroni A et al. (2005) Point mutations in apolipoprotein A-I mimic the phenotype observed in patients with classical lecithin:cholesterol acyltransferase deficiency. Biochemistry 44: 14353-66 PubMed GONUTS page
- ↑ Hirsch-Reinshagen V et al. (2009) LCAT synthesized by primary astrocytes esterifies cholesterol on glia-derived lipoproteins. J Lipid Res 50: 885-93 PubMed GONUTS page
