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MGI:Lbx1
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Lbx1 ( synonyms: Lbx1h ) | |
| Protein Name(s) | ladybird homeobox homolog 1 (Drosophila), | |
| External Links | ||
| MGI | MGI:104867 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000976 |
transcription regulatory region sequence-specific DNA binding |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0001947 |
heart looping |
MGI:MGI:3628723 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2386948 |
P |
From MGI |
||
| GO:0003677 |
DNA binding |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0238 |
F |
From MGI |
||
| GO:0003677 |
DNA binding |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0003700 |
sequence-specific DNA binding transcription factor activity |
MGI:MGI:3574120 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3574120 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0539 |
C |
From MGI |
||
| GO:0005634 |
nucleus |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
C |
From MGI |
|||
| GO:0005667 |
transcription factor complex |
MGI:MGI:3574120 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0006351 |
transcription, DNA-dependent |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0804 |
P |
From MGI |
||
| GO:0006355 |
regulation of transcription, DNA-dependent |
MGI:MGI:3574120 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0007275 |
multicellular organismal development |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0217 |
P |
From MGI |
||
| GO:0007399 |
nervous system development |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0524 |
P |
From MGI |
||
| GO:0007517 |
muscle organ development |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0517 |
P |
From MGI |
||
| GO:0008285 |
negative regulation of cell proliferation |
MGI:MGI:3628723 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2386948 |
P |
From MGI |
||
| GO:0021920 |
regulation of transcription from RNA polymerase II promoter involved in spinal cord association neuron specification |
MGI:MGI:2179903 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2182635 |
P |
From MGI |
||
| GO:0030154 |
cell differentiation |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0221 |
P |
From MGI |
||
| GO:0043565 |
sequence-specific DNA binding |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0045665 |
negative regulation of neuron differentiation |
MGI:MGI:3607682 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2182635 |
P |
From MGI |
||
| GO:0048663 |
neuron fate commitment |
MGI:MGI:2179904 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1352738 |
P |
From MGI |
||
| GO:0048664 |
neuron fate determination |
MGI:MGI:3607682 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:1351209 |
P |
From MGI |
||
| GO:0048664 |
neuron fate determination |
MGI:MGI:3607682 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2182635 |
P |
From MGI |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Schäfer K et al. (2003) The homeobox gene Lbx1 specifies a subpopulation of cardiac neural crest necessary for normal heart development. Circ Res 92: 73-80 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 Mizuhara E et al. (2005) Corl1, a novel neuronal lineage-specific transcriptional corepressor for the homeodomain transcription factor Lbx1. J Biol Chem 280: 3645-55 PubMed GONUTS page
- ↑ Gross MK et al. (2002) Lbx1 specifies somatosensory association interneurons in the dorsal spinal cord. Neuron 34: 535-49 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 Cheng L et al. (2005) Lbx1 and Tlx3 are opposing switches in determining GABAergic versus glutamatergic transmitter phenotypes. Nat Neurosci 8: 1510-5 PubMed GONUTS page
- ↑ Müller T et al. (2002) The homeodomain factor lbx1 distinguishes two major programs of neuronal differentiation in the dorsal spinal cord. Neuron 34: 551-62 PubMed GONUTS page
