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MGI:Lamb1
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Lamb1 ( synonyms: C80098, C81607, Lamb-1, Lamb1-1 ) | |
| Protein Name(s) | laminin B1, | |
| External Links | ||
| MGI | MGI:96743 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0005178 |
integrin binding |
MGI:MGI:84972 |
IMP: Inferred from Mutant Phenotype |
F |
From MGI |
|||
| GO:0005201 |
extracellular matrix structural constituent |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:2662649 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:4412469 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005576 |
extracellular region |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0964 |
C |
From MGI |
||
| GO:0005578 |
proteinaceous extracellular matrix |
MGI:MGI:3624056 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005604 |
basement membrane |
MGI:MGI:2662649 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005604 |
basement membrane |
MGI:MGI:3045829 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005604 |
basement membrane |
MGI:MGI:3579951 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005604 |
basement membrane |
MGI:MGI:3610934 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005604 |
basement membrane |
MGI:MGI:3776221 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005604 |
basement membrane |
MGI:MGI:3807344 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005604 |
basement membrane |
MGI:MGI:4441265 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005604 |
basement membrane |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005604 |
basement membrane |
MGI:MGI:52425 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005605 |
basal lamina |
MGI:MGI:1101275 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005606 |
laminin-1 complex |
MGI:MGI:1095193 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005606 |
laminin-1 complex |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005607 |
laminin-2 complex |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005615 |
extracellular space |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0007155 |
cell adhesion |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0130 |
P |
From MGI |
||
| GO:0007162 |
negative regulation of cell adhesion |
MGI:MGI:4412469 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0007566 |
embryo implantation |
MGI:MGI:3045829 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3048667 |
P |
From MGI |
||
| GO:0007611 |
learning or memory |
MGI:MGI:3046598 |
NAS: Non-traceable Author Statement |
P |
From MGI |
|||
| GO:0016477 |
cell migration |
MGI:MGI:84972 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0019899 |
enzyme binding |
MGI:MGI:3056824 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0030335 |
positive regulation of cell migration |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0031012 |
extracellular matrix |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_001100191 |
C |
From MGI |
||
| GO:0031175 |
neuron projection development |
MGI:MGI:3836888 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0031175 |
neuron projection development |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0034446 |
substrate adhesion-dependent cell spreading |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0042476 |
odontogenesis |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0043208 |
glycosphingolipid binding |
MGI:MGI:3836888 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0043256 |
laminin complex |
MGI:MGI:67497 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0043257 |
laminin-8 complex |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0043259 |
laminin-10 complex |
MGI:MGI:1097278 |
IPI: Inferred from Physical Interaction |
C |
From MGI |
|||
| GO:0043259 |
laminin-10 complex |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0048471 |
perinuclear region of cytoplasm |
MGI:MGI:3046598 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
|
colocalizes_with |
GO:0005604 |
basement membrane |
MGI:MGI:1095193 |
IDA: Inferred from Direct Assay |
C |
From MGI |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Yao CC et al. (1996) Laminins promote the locomotion of skeletal myoblasts via the alpha 7 integrin receptor. J Cell Sci 109 ( Pt 13): 3139-50 PubMed GONUTS page
- ↑ 2.0 2.1 Li J et al. (2003) Laminin-10 is crucial for hair morphogenesis. EMBO J 22: 2400-10 PubMed GONUTS page
- ↑ 3.0 3.1 Underwood PA et al. (1995) Evidence for the location of a binding sequence for the alpha 2 beta 1 integrin of endothelial cells, in the beta 1 subunit of laminin. Biochem J 309 ( Pt 3): 765-71 PubMed GONUTS page
- ↑ Bajanca F et al. (2006) Integrin alpha6beta1-laminin interactions regulate early myotome formation in the mouse embryo. Development 133: 1635-44 PubMed GONUTS page
- ↑ 5.0 5.1 Miner JH et al. (2004) Compositional and structural requirements for laminin and basement membranes during mouse embryo implantation and gastrulation. Development 131: 2247-56 PubMed GONUTS page
- ↑ Gersdorff N et al. (2005) Basement membrane composition in the early mouse embryo day 7. Dev Dyn 233: 1140-8 PubMed GONUTS page
- ↑ Abrahamson DR et al. (2003) Laminin-1 reexpression in Alport mouse glomerular basement membranes. Kidney Int 63: 826-34 PubMed GONUTS page
- ↑ Meyer zum Gottesberge AM & Felix H (2005) Abnormal basement membrane in the inner ear and the kidney of the Mpv17-/- mouse strain: ultrastructural and immunohistochemical investigations. Histochem Cell Biol 124: 507-16 PubMed GONUTS page
- ↑ Manabe R et al. (2008) Transcriptome-based systematic identification of extracellular matrix proteins. Proc Natl Acad Sci U S A 105: 12849-54 PubMed GONUTS page
- ↑ Schéele S et al. (2006) Monoclonal anti-mouse laminin antibodies: AL-1 reacts with laminin alpha1 chain, AL-2 with laminin beta1 chain, and AL-4 with the coiled-coil domain of laminin beta1 chain. Matrix Biol 25: 301-5 PubMed GONUTS page
- ↑ Schuger L et al. (1992) Laminin expression in the mouse lung increases with development and stimulates spontaneous organotypic rearrangement of mixed lung cells. Dev Dyn 195: 43-54 PubMed GONUTS page
- ↑ Patton BL et al. (1997) Distribution and function of laminins in the neuromuscular system of developing, adult, and mutant mice. J Cell Biol 139: 1507-21 PubMed GONUTS page
- ↑ 13.0 13.1 Qin P et al. (1997) Localization of basement membrane-associated protein isoforms during development of the ocular surface of mouse eye. Dev Dyn 209: 367-76 PubMed GONUTS page
- ↑ 14.0 14.1 Sharif KA et al. (2004) Differential regulation of laminin b1 transgene expression in the neonatal and adult mouse brain. Neuroscience 126: 967-78 PubMed GONUTS page
- ↑ Paraoanu LE & Layer PG (2004) Mouse acetylcholinesterase interacts in yeast with the extracellular matrix component laminin-1beta. FEBS Lett 576: 161-4 PubMed GONUTS page
- ↑ 16.0 16.1 Ichikawa N et al. (2009) Binding of laminin-1 to monosialoganglioside GM1 in lipid rafts is crucial for neurite outgrowth. J Cell Sci 122: 289-99 PubMed GONUTS page
- ↑ Utani A et al. (1994) Laminin chain assembly. Specific sequences at the C terminus of the long arm are required for the formation of specific double- and triple-stranded coiled-coil structures. J Biol Chem 269: 19167-75 PubMed GONUTS page
- ↑ Sorokin LM et al. (1997) Developmental regulation of the laminin alpha5 chain suggests a role in epithelial and endothelial cell maturation. Dev Biol 189: 285-300 PubMed GONUTS page
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