GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.
You can help reduce stress on the server by:
- not reloading pages frequently - this just adds
- opening links in new windows (so you can read the old page)
MGI:Krt8
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Krt8 ( synonyms: Card2, cytokeratin 8, cytokeratin-8, cytokeratin8, EndoA, K8, Krt-2.8, Krt2-8 ) | |
| Protein Name(s) | keratin 8, | |
| External Links | ||
| MGI | MGI:96705 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000904 |
cell morphogenesis involved in differentiation |
MGI:MGI:58154 |
TAS: Traceable Author Statement |
P |
From MGI |
|||
| GO:0005198 |
structural molecule activity |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3759340 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0539 |
C |
From MGI |
||
| GO:0005737 |
cytoplasm |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005882 |
intermediate filament |
MGI:MGI:3711847 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0006915 |
apoptotic process |
MGI:MGI:3711847 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2178042 |
P |
From MGI |
||
| GO:0007275 |
multicellular organismal development |
MGI:MGI:58154 |
TAS: Traceable Author Statement |
P |
From MGI |
|||
| GO:0016010 |
dystrophin-associated glycoprotein complex |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0030018 |
Z disc |
MGI:MGI:3057089 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0030018 |
Z disc |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0032403 |
protein complex binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0033209 |
tumor necrosis factor-mediated signaling pathway |
MGI:MGI:3711847 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:96692 |
P |
From MGI |
||
| GO:0033209 |
tumor necrosis factor-mediated signaling pathway |
MGI:MGI:3711847 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2178042 |
P |
From MGI |
||
| GO:0042383 |
sarcolemma |
MGI:MGI:3057089 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0042383 |
sarcolemma |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0043034 |
costamere |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0045095 |
keratin filament |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0045214 |
sarcomere organization |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0051599 |
response to hydrostatic pressure |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0051707 |
response to other organism |
MGI:MGI:2681370 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2178042 |
P |
From MGI |
||
| GO:0060706 |
cell differentiation involved in embryonic placenta development |
MGI:MGI:1926669 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:96693 |
P |
From MGI |
||
| GO:0071944 |
cell periphery |
MGI:MGI:4821247 |
IDA: Inferred from Direct Assay |
C |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Ouellet T et al. (1988) Complete sequence of the mouse type-II keratin EndoA: its amino-terminal region resembles mitochondrial signal peptides. Gene 70: 75-84 PubMed GONUTS page
- ↑ Zhou Q et al. (2003) Keratin 20 helps maintain intermediate filament organization in intestinal epithelia. Mol Biol Cell 14: 2959-71 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 Caulin C et al. (2000) Keratin-dependent, epithelial resistance to tumor necrosis factor-induced apoptosis. J Cell Biol 149: 17-22 PubMed GONUTS page
- ↑ 4.0 4.1 Ursitti JA et al. (2004) Cloning and characterization of cytokeratins 8 and 19 in adult rat striated muscle. Interaction with the dystrophin glycoprotein complex. J Biol Chem 279: 41830-8 PubMed GONUTS page
- ↑ Tao GZ et al. (2003) Keratin-8 null mice have different gallbladder and liver susceptibility to lithogenic diet-induced injury. J Cell Sci 116: 4629-38 PubMed GONUTS page
- ↑ Tamai Y et al. (2000) Cytokeratins 8 and 19 in the mouse placental development. J Cell Biol 151: 563-72 PubMed GONUTS page
- ↑ Gu B et al. (2009) Pygo2 expands mammary progenitor cells by facilitating histone H3 K4 methylation. J Cell Biol 185: 811-26 PubMed GONUTS page
