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MGI:Klb
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Klb ( synonyms: betaKlotho ) | |
| Protein Name(s) | klotho beta, | |
| External Links | ||
| MGI | MGI:1932466 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0003824 |
catalytic activity |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0004553 |
hydrolase activity, hydrolyzing O-glycosyl compounds |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0005886 |
plasma membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-1003 |
C |
From MGI |
||
| GO:0005975 |
carbohydrate metabolic process |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0008284 |
positive regulation of cell proliferation |
MGI:MGI:4361675 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:95524 |
P |
From MGI |
||
| GO:0008543 |
fibroblast growth factor receptor signaling pathway |
MGI:MGI:4361675 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:95524 |
P |
From MGI |
||
| GO:0016020 |
membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0472 |
C |
From MGI |
||
| GO:0016021 |
integral to membrane |
MGI:MGI:1197786 |
ISS: Inferred from Sequence or Structural Similarity |
C |
From MGI |
|||
| GO:0017134 |
fibroblast growth factor binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0043169 |
cation binding |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0090080 |
positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway |
MGI:MGI:4361675 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:1861377 |
P |
From MGI |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 Suzuki M et al. (2008) betaKlotho is required for fibroblast growth factor (FGF) 21 signaling through FGF receptor (FGFR) 1c and FGFR3c. Mol Endocrinol 22: 1006-14 PubMed GONUTS page
- ↑ Shiraki-Iida T et al. (1998) Structure of the mouse klotho gene and its two transcripts encoding membrane and secreted protein. FEBS Lett 424: 6-10 PubMed GONUTS page
