MGI:Kit

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Annotations

Qualifier	GO ID	GO term name	Reference	Evidence Code	with/from	Aspect	Notes
	GO:0000166	nucleotide binding	MGI:MGI:1354194	IEA: Inferred from Electronic Annotation	UniProtKB-KW:KW-0547	F	From MGI
	GO:0000187	activation of MAPK activity	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:P10721	P	From MGI
	GO:0001669	acrosomal vesicle	MGI:MGI:4417868	ISO: Inferred from Sequence Orthology	UniProtKB:Q63116	C	From MGI
	GO:0002020	protease binding	MGI:MGI:4942254 PMID:12135759^[1]	IPI: Inferred from Physical Interaction	UniProtKB:Q05910	F	From MGI
	GO:0002318	myeloid progenitor cell differentiation	MGI:MGI:74655 PMID:7621074^[2]	IGI: Inferred from Genetic Interaction	MGI:MGI:95559	P	From MGI
	GO:0002320	lymphoid progenitor cell differentiation	MGI:MGI:74655 PMID:7621074^[2]	IGI: Inferred from Genetic Interaction	MGI:MGI:95559	P	From MGI
	GO:0002573	myeloid leukocyte differentiation	MGI:MGI:3778714 PMID:18258601^[3]	IMP: Inferred from Mutant Phenotype	MGI:MGI:1856265	P	From MGI
	GO:0004672	protein kinase activity	MGI:MGI:2152098	IEA: Inferred from Electronic Annotation	InterPro:IPR000719 InterPro:IPR001245	F	From MGI
	GO:0004713	protein tyrosine kinase activity	MGI:MGI:4417868	ISO: Inferred from Sequence Orthology	UniProtKB:Q63116	F	From MGI
	GO:0004714	transmembrane receptor protein tyrosine kinase activity	MGI:MGI:4417868	ISO: Inferred from Sequence Orthology	UniProtKB:Q63116	F	From MGI
	GO:0004714	transmembrane receptor protein tyrosine kinase activity	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:P10721	F	From MGI
	GO:0004872	receptor activity	MGI:MGI:1354194	IEA: Inferred from Electronic Annotation	UniProtKB-KW:KW-0675	F	From MGI
	GO:0005020	stem cell factor receptor activity	MGI:MGI:1859033 PMID:10872802^[4]	IDA: Inferred from Direct Assay		F	From MGI
	GO:0005515	protein binding	MGI:MGI:1859033 PMID:10872802^[4]	IPI: Inferred from Physical Interaction	UniProtKB:Q9JID9	F	From MGI
	GO:0005515	protein binding	MGI:MGI:2178875 PMID:11805142^[5]	IPI: Inferred from Physical Interaction	UniProtKB:O09039	F	From MGI
	GO:0005515	protein binding	MGI:MGI:59197 PMID:1698557^[6]	IPI: Inferred from Physical Interaction	UniProtKB:P20826	F	From MGI
	GO:0005524	ATP binding	MGI:MGI:1354194	IEA: Inferred from Electronic Annotation	UniProtKB-KW:KW-0067	F	From MGI
	GO:0005524	ATP binding	MGI:MGI:2152098	IEA: Inferred from Electronic Annotation	InterPro:IPR000719 InterPro:IPR017441 InterPro:IPR016243 InterPro:IPR001824	F	From MGI
	GO:0005615	extracellular space	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:P10721	C	From MGI
	GO:0005622	intracellular	MGI:MGI:1859033 PMID:10872802^[4]	IDA: Inferred from Direct Assay		C	From MGI
	GO:0005634	nucleus	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:P10721	C	From MGI
	GO:0005737	cytoplasm	MGI:MGI:4417868	ISO: Inferred from Sequence Orthology	UniProtKB:Q63116	C	From MGI
	GO:0005737	cytoplasm	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:P10721	C	From MGI
	GO:0005886	plasma membrane	MGI:MGI:1354194	IEA: Inferred from Electronic Annotation	UniProtKB-KW:KW-1003	C	From MGI
	GO:0006468	protein phosphorylation	MGI:MGI:2178875 PMID:11805142^[5]	IDA: Inferred from Direct Assay		P	From MGI
	GO:0006687	glycosphingolipid metabolic process	MGI:MGI:3797995 PMID:18308723^[7]	IMP: Inferred from Mutant Phenotype	MGI:MGI:1856232	P	From MGI
	GO:0006935	chemotaxis	MGI:MGI:2384228 PMID:12140361^[8]	TAS: Traceable Author Statement		P	From MGI
	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway	MGI:MGI:2152098	IEA: Inferred from Electronic Annotation	InterPro:IPR016243 InterPro:IPR001824	P	From MGI
	GO:0007243	intracellular protein kinase cascade	MGI:MGI:1859033 PMID:10872802^[4]	IDA: Inferred from Direct Assay		P	From MGI
	GO:0007281	germ cell development	MGI:MGI:2384228 PMID:12140361^[8]	TAS: Traceable Author Statement		P	From MGI
	GO:0007283	spermatogenesis	MGI:MGI:4417868	ISO: Inferred from Sequence Orthology	UniProtKB:Q63116	P	From MGI
	GO:0007286	spermatid development	MGI:MGI:3797995 PMID:18308723^[7]	IMP: Inferred from Mutant Phenotype	MGI:MGI:1856232	P	From MGI
	GO:0008284	positive regulation of cell proliferation	MGI:MGI:1351242 PMID:10620616^[9]	IGI: Inferred from Genetic Interaction	MGI:MGI:96974 MGI:MGI:97306	P	From MGI
	GO:0008284	positive regulation of cell proliferation	MGI:MGI:4417868	ISO: Inferred from Sequence Orthology	UniProtKB:Q63116	P	From MGI
	GO:0008354	germ cell migration	MGI:MGI:4417868	ISO: Inferred from Sequence Orthology	UniProtKB:Q63116	P	From MGI
	GO:0008542	visual learning	MGI:MGI:4417868	ISO: Inferred from Sequence Orthology	UniProtKB:Q63116	P	From MGI
	GO:0009314	response to radiation	MGI:MGI:2668295 PMID:12833143^[10]	IMP: Inferred from Mutant Phenotype	MGI:MGI:1856266	P	From MGI
	GO:0009897	external side of plasma membrane	MGI:MGI:1860996 PMID:10943842^[11]	IDA: Inferred from Direct Assay		C	From MGI
	GO:0009897	external side of plasma membrane	MGI:MGI:2668377 PMID:12900455^[12]	IDA: Inferred from Direct Assay		C	From MGI
	GO:0009897	external side of plasma membrane	MGI:MGI:2670544 PMID:12714518^[13]	IDA: Inferred from Direct Assay		C	From MGI
	GO:0009897	external side of plasma membrane	MGI:MGI:2670545 PMID:12714519^[14]	IDA: Inferred from Direct Assay		C	From MGI
	GO:0009897	external side of plasma membrane	MGI:MGI:3041277 PMID:14990792^[15]	IDA: Inferred from Direct Assay		C	From MGI
	GO:0009897	external side of plasma membrane	MGI:MGI:3581459 PMID:15909309^[16]	IDA: Inferred from Direct Assay		C	From MGI
	GO:0009897	external side of plasma membrane	MGI:MGI:3605581 PMID:15947484^[17]	IDA: Inferred from Direct Assay		C	From MGI
	GO:0009897	external side of plasma membrane	MGI:MGI:3610843 PMID:16287714^[18]	IDA: Inferred from Direct Assay		C	From MGI
	GO:0009897	external side of plasma membrane	MGI:MGI:3829828 PMID:18958875^[19]	IDA: Inferred from Direct Assay		C	From MGI
	GO:0009897	external side of plasma membrane	MGI:MGI:3835249 PMID:18971422^[20]	IDA: Inferred from Direct Assay		C	From MGI
	GO:0009897	external side of plasma membrane	MGI:MGI:4415096 PMID:19934022^[21]	IDA: Inferred from Direct Assay		C	From MGI
	GO:0009897	external side of plasma membrane	MGI:MGI:4417868	ISO: Inferred from Sequence Orthology	UniProtKB:Q63116	C	From MGI
	GO:0009897	external side of plasma membrane	MGI:MGI:5052199 PMID:21708977^[22]	IDA: Inferred from Direct Assay		C	From MGI
	GO:0009898	internal side of plasma membrane	MGI:MGI:4417868	ISO: Inferred from Sequence Orthology	UniProtKB:Q63116	C	From MGI
	GO:0009986	cell surface	MGI:MGI:1097217 PMID:9324354^[23]	IDA: Inferred from Direct Assay		C	From MGI
	GO:0009986	cell surface	MGI:MGI:893847 PMID:9216738^[24]	IDA: Inferred from Direct Assay		C	From MGI
	GO:0010628	positive regulation of gene expression	MGI:MGI:3797995 PMID:18308723^[7]	IMP: Inferred from Mutant Phenotype	MGI:MGI:1856232	P	From MGI
	GO:0016020	membrane	MGI:MGI:1354194	IEA: Inferred from Electronic Annotation	UniProtKB-KW:KW-0472	C	From MGI
	GO:0016020	membrane	MGI:MGI:2152098	IEA: Inferred from Electronic Annotation	InterPro:IPR001824	C	From MGI
	GO:0016021	integral to membrane	MGI:MGI:1354194	IEA: Inferred from Electronic Annotation	UniProtKB-KW:KW-0812	C	From MGI
	GO:0016021	integral to membrane	MGI:MGI:2152098	IEA: Inferred from Electronic Annotation	InterPro:IPR016243	C	From MGI
	GO:0016301	kinase activity	MGI:MGI:1354194	IEA: Inferred from Electronic Annotation	UniProtKB-KW:KW-0418	F	From MGI
	GO:0016310	phosphorylation	MGI:MGI:1354194	IEA: Inferred from Electronic Annotation	UniProtKB-KW:KW-0418	P	From MGI
	GO:0016740	transferase activity	MGI:MGI:1354194	IEA: Inferred from Electronic Annotation	UniProtKB-KW:KW-0808	F	From MGI
	GO:0016772	transferase activity, transferring phosphorus-containing groups	MGI:MGI:2152098	IEA: Inferred from Electronic Annotation	InterPro:IPR011009	F	From MGI
	GO:0018108	peptidyl-tyrosine phosphorylation	MGI:MGI:1859033 PMID:10872802^[4]	IDA: Inferred from Direct Assay		P	From MGI
	GO:0018108	peptidyl-tyrosine phosphorylation	MGI:MGI:4417868	ISO: Inferred from Sequence Orthology	UniProtKB:Q63116	P	From MGI
	GO:0018108	peptidyl-tyrosine phosphorylation	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:P10721	P	From MGI
	GO:0019221	cytokine-mediated signaling pathway	MGI:MGI:1859033 PMID:10872802^[4]	IDA: Inferred from Direct Assay		P	From MGI
	GO:0019221	cytokine-mediated signaling pathway	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:P10721	P	From MGI
	GO:0019955	cytokine binding	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:P10721	F	From MGI
	GO:0030097	hemopoiesis	MGI:MGI:2178875 PMID:11805142^[5]	IMP: Inferred from Mutant Phenotype	MGI:MGI:1856232	P	From MGI
	GO:0030154	cell differentiation	MGI:MGI:2384228 PMID:12140361^[8]	TAS: Traceable Author Statement		P	From MGI
	GO:0030335	positive regulation of cell migration	MGI:MGI:4417868	ISO: Inferred from Sequence Orthology	UniProtKB:Q63116	P	From MGI
	GO:0031274	positive regulation of pseudopodium assembly	MGI:MGI:4417868	ISO: Inferred from Sequence Orthology	UniProtKB:Q63116	P	From MGI
	GO:0035019	somatic stem cell maintenance	MGI:MGI:4417868	ISO: Inferred from Sequence Orthology	UniProtKB:Q63116	P	From MGI
	GO:0035234	germ cell programmed cell death	MGI:MGI:2680318 PMID:14660547^[25]	IGI: Inferred from Genetic Interaction	MGI:MGI:99702	P	From MGI
	GO:0042511	positive regulation of tyrosine phosphorylation of Stat1 protein	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:P10721	P	From MGI
	GO:0042517	positive regulation of tyrosine phosphorylation of Stat3 protein	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:P10721	P	From MGI
	GO:0042523	positive regulation of tyrosine phosphorylation of Stat5 protein	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:P10721	P	From MGI
	GO:0042803	protein homodimerization activity	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:P10721	F	From MGI
	GO:0043069	negative regulation of programmed cell death	MGI:MGI:2680318 PMID:14660547^[25]	IGI: Inferred from Genetic Interaction	MGI:MGI:99702	P	From MGI
	GO:0043069	negative regulation of programmed cell death	MGI:MGI:3797995 PMID:18308723^[7]	IMP: Inferred from Mutant Phenotype	MGI:MGI:1856232	P	From MGI
	GO:0043406	positive regulation of MAP kinase activity	MGI:MGI:1351242 PMID:10620616^[9]	IGI: Inferred from Genetic Interaction	MGI:MGI:96974 MGI:MGI:97306	P	From MGI
	GO:0043410	positive regulation of MAPK cascade	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:P10721	P	From MGI
	GO:0043473	pigmentation	MGI:MGI:1351242 PMID:10620616^[9]	IGI: Inferred from Genetic Interaction	MGI:MGI:97306	P	From MGI
	GO:0045747	positive regulation of Notch signaling pathway	MGI:MGI:4417868	ISO: Inferred from Sequence Orthology	UniProtKB:Q63116	P	From MGI
	GO:0046427	positive regulation of JAK-STAT cascade	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:P10721	P	From MGI
	GO:0046777	protein autophosphorylation	MGI:MGI:2384228 PMID:12140361^[8]	TAS: Traceable Author Statement		P	From MGI
	GO:0046777	protein autophosphorylation	MGI:MGI:4417868	ISO: Inferred from Sequence Orthology	UniProtKB:Q63116	P	From MGI
	GO:0046777	protein autophosphorylation	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:P10721	P	From MGI
	GO:0046872	metal ion binding	MGI:MGI:1354194	IEA: Inferred from Electronic Annotation	UniProtKB-KW:KW-0479	F	From MGI
	GO:0048066	developmental pigmentation	MGI:MGI:3055244 PMID:15322542^[26]	IMP: Inferred from Mutant Phenotype	MGI:MGI:1856266	P	From MGI
	GO:0048070	regulation of developmental pigmentation	MGI:MGI:3778519 PMID:18454205^[27]	IGI: Inferred from Genetic Interaction	MGI:MGI:2660628	P	From MGI
	GO:0048070	regulation of developmental pigmentation	MGI:MGI:3778519 PMID:18454205^[27]	IMP: Inferred from Mutant Phenotype	MGI:MGI:2449782 MGI:MGI:1856164 MGI:MGI:1856161	P	From MGI
	GO:0048103	somatic stem cell division	MGI:MGI:4417868	ISO: Inferred from Sequence Orthology	UniProtKB:Q63116	P	From MGI
	GO:0048170	positive regulation of long-term neuronal synaptic plasticity	MGI:MGI:4417868	ISO: Inferred from Sequence Orthology	UniProtKB:Q63116	P	From MGI
	GO:0050673	epithelial cell proliferation	MGI:MGI:4417868	ISO: Inferred from Sequence Orthology	UniProtKB:Q63116	P	From MGI
	GO:0051091	positive regulation of sequence-specific DNA binding transcription factor activity	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:P10721	P	From MGI
	GO:0097067	cellular response to thyroid hormone stimulus	MGI:MGI:5306571 PMID:19375645^[28]	IDA: Inferred from Direct Assay		P	From MGI
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ Amour A et al. (2002) The enzymatic activity of ADAM8 and ADAM9 is not regulated by TIMPs. FEBS Lett 524: 154-8 PubMed GONUTS page
↑ ^2.0 ^2.1 Mackarehtschian K et al. (1995) Targeted disruption of the flk2/flt3 gene leads to deficiencies in primitive hematopoietic progenitors. Immunity 3: 147-61 PubMed GONUTS page
↑ Sinnamon MJ et al. (2008) A protective role of mast cells in intestinal tumorigenesis. Carcinogenesis 29: 880-6 PubMed GONUTS page
↑ ^4.0 ^4.1 ^4.2 ^4.3 ^4.4 ^4.5 Iseki M et al. (2000) Molecular cloning of the mouse APS as a member of the Lnk family adaptor proteins. Biochem Biophys Res Commun 272: 45-54 PubMed GONUTS page
↑ ^5.0 ^5.1 ^5.2 Takaki S et al. (2002) Enhanced hematopoiesis by hematopoietic progenitor cells lacking intracellular adaptor protein, Lnk. J Exp Med 195: 151-60 PubMed GONUTS page
↑ Huang E et al. (1990) The hematopoietic growth factor KL is encoded by the Sl locus and is the ligand of the c-kit receptor, the gene product of the W locus. Cell 63: 225-33 PubMed GONUTS page
↑ ^7.0 ^7.1 ^7.2 ^7.3 Rabionet M et al. (2008) Male germ cells require polyenoic sphingolipids with complex glycosylation for completion of meiosis: a link to ceramide synthase-3. J Biol Chem 283: 13357-69 PubMed GONUTS page
↑ ^8.0 ^8.1 ^8.2 ^8.3 De Miguel MP et al. (2002) Dissection of the c-Kit signaling pathway in mouse primordial germ cells by retroviral-mediated gene transfer. Proc Natl Acad Sci U S A 99: 10458-63 PubMed GONUTS page
↑ ^9.0 ^9.1 ^9.2 Ingram DA et al. (2000) Genetic and biochemical evidence that haploinsufficiency of the Nf1 tumor suppressor gene modulates melanocyte and mast cell fates in vivo. J Exp Med 191: 181-8 PubMed GONUTS page
↑ Pérez-Losada J et al. (2003) The radioresistance biological function of the SCF/kit signaling pathway is mediated by the zinc-finger transcription factor Slug. Oncogene 22: 4205-11 PubMed GONUTS page
↑ Tamura K et al. (2000) Requirement for p38alpha in erythropoietin expression: a role for stress kinases in erythropoiesis. Cell 102: 221-31 PubMed GONUTS page
↑ Ferkowicz MJ et al. (2003) CD41 expression defines the onset of primitive and definitive hematopoiesis in the murine embryo. Development 130: 4393-403 PubMed GONUTS page
↑ Shelburne CP et al. (2003) Stat5 expression is critical for mast cell development and survival. Blood 102: 1290-7 PubMed GONUTS page
↑ Nemeth MJ et al. (2003) Hmgb3: an HMG-box family member expressed in primitive hematopoietic cells that inhibits myeloid and B-cell differentiation. Blood 102: 1298-306 PubMed GONUTS page
↑ Carlyle JR et al. (2004) Missing self-recognition of Ocil/Clr-b by inhibitory NKR-P1 natural killer cell receptors. Proc Natl Acad Sci U S A 101: 3527-32 PubMed GONUTS page
↑ Erlandsson L et al. (2005) Both the pre-BCR and the IL-7Ralpha are essential for expansion at the pre-BII cell stage in vivo. Eur J Immunol 35: 1969-76 PubMed GONUTS page
↑ Ikeda K et al. (2005) Stat5a is essential for the proliferation and survival of murine mast cells. Int Arch Allergy Immunol 137 Suppl 1: 45-50 PubMed GONUTS page
↑ Bultman SJ et al. (2005) A Brg1 mutation that uncouples ATPase activity from chromatin remodeling reveals an essential role for SWI/SNF-related complexes in beta-globin expression and erythroid development. Genes Dev 19: 2849-61 PubMed GONUTS page
↑ Jia J et al. (2008) E proteins are required to activate germline transcription of the TCR Vbeta8.2 gene. Eur J Immunol 38: 2806-20 PubMed GONUTS page
↑ Levi BP et al. (2009) Aldehyde dehydrogenase 1a1 is dispensable for stem cell function in the mouse hematopoietic and nervous systems. Blood 113: 1670-80 PubMed GONUTS page
↑ Hosoya T et al. (2009) GATA-3 is required for early T lineage progenitor development. J Exp Med 206: 2987-3000 PubMed GONUTS page
↑ Crippa S et al. (2011) miR669a and miR669q prevent skeletal muscle differentiation in postnatal cardiac progenitors. J Cell Biol 193: 1197-212 PubMed GONUTS page
↑ Yoder MC et al. (1997) Characterization of definitive lymphohematopoietic stem cells in the day 9 murine yolk sac. Immunity 7: 335-44 PubMed GONUTS page
↑ Pharr PN & Hofbauer A (1997) Loss of flk-2/flt3 expression during commitment of multipotent mouse hematopoietic progenitor cells to the mast cell lineage. Exp Hematol 25: 620-8 PubMed GONUTS page
↑ ^25.0 ^25.1 Stallock J et al. (2003) The pro-apoptotic gene Bax is required for the death of ectopic primordial germ cells during their migration in the mouse embryo. Development 130: 6589-97 PubMed GONUTS page
↑ Van Raamsdonk CD et al. (2004) Effects of G-protein mutations on skin color. Nat Genet 36: 961-8 PubMed GONUTS page
↑ ^27.0 ^27.1 Silver DL et al. (2008) The secreted metalloprotease ADAMTS20 is required for melanoblast survival. PLoS Genet 4: e1000003 PubMed GONUTS page
↑ Gamper I et al. (2009) GAR22: a novel target gene of thyroid hormone receptor causes growth inhibition in human erythroid cells. Exp Hematol 37: 539-548.e4 PubMed GONUTS page

[PMID:12135759-0] Amour A et al. (2002) The enzymatic activity of ADAM8 and ADAM9 is not regulated by TIMPs. FEBS Lett 524: 154-8 PubMed GONUTS page

[PMID:7621074-1] 2.0 ^2.1 Mackarehtschian K et al. (1995) Targeted disruption of the flk2/flt3 gene leads to deficiencies in primitive hematopoietic progenitors. Immunity 3: 147-61 PubMed GONUTS page

[PMID:18258601-2] Sinnamon MJ et al. (2008) A protective role of mast cells in intestinal tumorigenesis. Carcinogenesis 29: 880-6 PubMed GONUTS page

[PMID:10872802-3] 4.0 ^4.1 ^4.2 ^4.3 ^4.4 ^4.5 Iseki M et al. (2000) Molecular cloning of the mouse APS as a member of the Lnk family adaptor proteins. Biochem Biophys Res Commun 272: 45-54 PubMed GONUTS page

[PMID:11805142-4] 5.0 ^5.1 ^5.2 Takaki S et al. (2002) Enhanced hematopoiesis by hematopoietic progenitor cells lacking intracellular adaptor protein, Lnk. J Exp Med 195: 151-60 PubMed GONUTS page

[PMID:1698557-5] Huang E et al. (1990) The hematopoietic growth factor KL is encoded by the Sl locus and is the ligand of the c-kit receptor, the gene product of the W locus. Cell 63: 225-33 PubMed GONUTS page

[PMID:18308723-6] 7.0 ^7.1 ^7.2 ^7.3 Rabionet M et al. (2008) Male germ cells require polyenoic sphingolipids with complex glycosylation for completion of meiosis: a link to ceramide synthase-3. J Biol Chem 283: 13357-69 PubMed GONUTS page

[PMID:12140361-7] 8.0 ^8.1 ^8.2 ^8.3 De Miguel MP et al. (2002) Dissection of the c-Kit signaling pathway in mouse primordial germ cells by retroviral-mediated gene transfer. Proc Natl Acad Sci U S A 99: 10458-63 PubMed GONUTS page

[PMID:10620616-8] 9.0 ^9.1 ^9.2 Ingram DA et al. (2000) Genetic and biochemical evidence that haploinsufficiency of the Nf1 tumor suppressor gene modulates melanocyte and mast cell fates in vivo. J Exp Med 191: 181-8 PubMed GONUTS page

[PMID:12833143-9] Pérez-Losada J et al. (2003) The radioresistance biological function of the SCF/kit signaling pathway is mediated by the zinc-finger transcription factor Slug. Oncogene 22: 4205-11 PubMed GONUTS page

[PMID:10943842-10] Tamura K et al. (2000) Requirement for p38alpha in erythropoietin expression: a role for stress kinases in erythropoiesis. Cell 102: 221-31 PubMed GONUTS page

[PMID:12900455-11] Ferkowicz MJ et al. (2003) CD41 expression defines the onset of primitive and definitive hematopoiesis in the murine embryo. Development 130: 4393-403 PubMed GONUTS page

[PMID:12714518-12] Shelburne CP et al. (2003) Stat5 expression is critical for mast cell development and survival. Blood 102: 1290-7 PubMed GONUTS page

[PMID:12714519-13] Nemeth MJ et al. (2003) Hmgb3: an HMG-box family member expressed in primitive hematopoietic cells that inhibits myeloid and B-cell differentiation. Blood 102: 1298-306 PubMed GONUTS page

[PMID:14990792-14] Carlyle JR et al. (2004) Missing self-recognition of Ocil/Clr-b by inhibitory NKR-P1 natural killer cell receptors. Proc Natl Acad Sci U S A 101: 3527-32 PubMed GONUTS page

[PMID:15909309-15] Erlandsson L et al. (2005) Both the pre-BCR and the IL-7Ralpha are essential for expansion at the pre-BII cell stage in vivo. Eur J Immunol 35: 1969-76 PubMed GONUTS page

[PMID:15947484-16] Ikeda K et al. (2005) Stat5a is essential for the proliferation and survival of murine mast cells. Int Arch Allergy Immunol 137 Suppl 1: 45-50 PubMed GONUTS page

[PMID:16287714-17] Bultman SJ et al. (2005) A Brg1 mutation that uncouples ATPase activity from chromatin remodeling reveals an essential role for SWI/SNF-related complexes in beta-globin expression and erythroid development. Genes Dev 19: 2849-61 PubMed GONUTS page

[PMID:18958875-18] Jia J et al. (2008) E proteins are required to activate germline transcription of the TCR Vbeta8.2 gene. Eur J Immunol 38: 2806-20 PubMed GONUTS page

[PMID:18971422-19] Levi BP et al. (2009) Aldehyde dehydrogenase 1a1 is dispensable for stem cell function in the mouse hematopoietic and nervous systems. Blood 113: 1670-80 PubMed GONUTS page

[PMID:19934022-20] Hosoya T et al. (2009) GATA-3 is required for early T lineage progenitor development. J Exp Med 206: 2987-3000 PubMed GONUTS page

[PMID:21708977-21] Crippa S et al. (2011) miR669a and miR669q prevent skeletal muscle differentiation in postnatal cardiac progenitors. J Cell Biol 193: 1197-212 PubMed GONUTS page

[PMID:9324354-22] Yoder MC et al. (1997) Characterization of definitive lymphohematopoietic stem cells in the day 9 murine yolk sac. Immunity 7: 335-44 PubMed GONUTS page

[PMID:9216738-23] Pharr PN & Hofbauer A (1997) Loss of flk-2/flt3 expression during commitment of multipotent mouse hematopoietic progenitor cells to the mast cell lineage. Exp Hematol 25: 620-8 PubMed GONUTS page

[PMID:14660547-24] 25.0 ^25.1 Stallock J et al. (2003) The pro-apoptotic gene Bax is required for the death of ectopic primordial germ cells during their migration in the mouse embryo. Development 130: 6589-97 PubMed GONUTS page

[PMID:15322542-25] Van Raamsdonk CD et al. (2004) Effects of G-protein mutations on skin color. Nat Genet 36: 961-8 PubMed GONUTS page

[PMID:18454205-26] 27.0 ^27.1 Silver DL et al. (2008) The secreted metalloprotease ADAMTS20 is required for melanoblast survival. PLoS Genet 4: e1000003 PubMed GONUTS page

[PMID:19375645-27] Gamper I et al. (2009) GAR22: a novel target gene of thyroid hormone receptor causes growth inhibition in human erythroid cells. Exp Hematol 37: 539-548.e4 PubMed GONUTS page

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Species (Taxon ID)	Mus musculus (house mouse) (taxon:10090)
Gene Name(s)	Kit ( synonyms: belly-spot, c-KIT, CD117, Dominant white spotting, Gsfsco1, Gsfsco5, Gsfsow3, SCO1, SCO5, SOW3, Steel Factor Receptor, Tr-kit )
Protein Name(s)	kit oncogene,
External Links
MGI	MGI:96677

MGI:Kit

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