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MGI:Kdm1

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Kdm1 ( synonyms: Aof2, LSD1 )
Protein Name(s) lysine (K)-specific demethylase 1,
External Links
MGI MGI:1196256

Annotations

Qualifier GO ID GO term name Reference(s) Evidence Code with/from Aspect Notes Status
GO:0000122

negative regulation of transcription from RNA polymerase II promoter

MGI:MGI:3710033
PMID:17392792[1]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0000122

negative regulation of transcription from RNA polymerase II promoter

MGI:MGI:3710033
PMID:17392792[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3711205
MGI:MGI:3690467

P

From MGI

GO:0001701

in utero embryonic development

MGI:MGI:3710033
PMID:17392792[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3711561

P

From MGI

GO:0003700

transcription factor activity

MGI:MGI:3710033
PMID:17392792[1]

IDA: Inferred from Direct Assay

F

From MGI

GO:0005634

nucleus

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

SP_KW:KW-0539

C

From MGI

GO:0005634

nucleus

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR017366

C

From MGI

GO:0005667

transcription factor complex

MGI:MGI:3710033
PMID:17392792[1]

IDA: Inferred from Direct Assay

C

From MGI

GO:0006350

transcription

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

SP_KW:KW-0804

P

From MGI

GO:0007275

multicellular organismal development

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

SP_KW:KW-0217

P

From MGI

GO:0008134

transcription factor binding

MGI:MGI:3710033
PMID:17392792[1]

IPI: Inferred from Physical Interaction

UniProtKB:Q00286
UniProtKB:Q64318
UniProtKB:P31266
UniProtKB:Q6ZPI3
UniProtKB:O88712
UniProtKB:Q8C796

F

From MGI

GO:0008283

cell proliferation

MGI:MGI:3710033
PMID:17392792[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3711205
MGI:MGI:3690467

P

From MGI

GO:0009055

electron carrier activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR002937

F

From MGI

GO:0010553

negative regulation of gene-specific transcription from RNA polymerase II promoter

MGI:MGI:3849640
PMID:19497860[2]

IDA: Inferred from Direct Assay

P

From MGI

GO:0010843

promoter binding

MGI:MGI:3849640
PMID:19497860[2]

IDA: Inferred from Direct Assay

F

From MGI

GO:0016491

oxidoreductase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

SP_KW:KW-0560

F

From MGI

GO:0016491

oxidoreductase activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR002937,InterPro:IPR017366

F

From MGI

GO:0016568

chromatin modification

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

SP_KW:KW-0156

P

From MGI

GO:0016577

histone demethylation

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR017366

P

From MGI

GO:0021983

pituitary gland development

MGI:MGI:3710033
PMID:17392792[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3711205
MGI:MGI:3690467

P

From MGI

GO:0045449

regulation of transcription

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

SP_KW:KW-0805

P

From MGI

GO:0045449

regulation of transcription

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR017366

P

From MGI

GO:0045944

positive regulation of transcription from RNA polymerase II promoter

MGI:MGI:3710033
PMID:17392792[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3711205
MGI:MGI:3690467
MGI:MGI:3711561

P

From MGI

GO:0046886

positive regulation of hormone biosynthetic process

MGI:MGI:3710033
PMID:17392792[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3711205
MGI:MGI:3690467

P

From MGI

GO:0050660

FAD binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR017366

F

From MGI

GO:0055114

oxidation reduction

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

SP_KW:KW-0560

P

From MGI

GO:0055114

oxidation reduction

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR017366

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 1.8 1.9 Wang J et al. (2007) Opposing LSD1 complexes function in developmental gene activation and repression programmes. Nature 446: 882-7 PubMed GONUTS page
  2. 2.0 2.1 Hu X et al. (2009) LSD1-mediated epigenetic modification is required for TAL1 function and hematopoiesis. Proc Natl Acad Sci U S A 106: 10141-6 PubMed GONUTS page
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