MGI:Kcnma1

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Annotations

Qualifier	GO ID	GO term name	Reference	Evidence Code	with/from	Aspect	Notes
	GO:0000166	nucleotide binding	MGI:MGI:2152098	IEA: Inferred from Electronic Annotation	InterPro:IPR016040	F	From MGI
	GO:0001666	response to hypoxia	MGI:MGI:3611743 PMID:16306267^[1]	IDA: Inferred from Direct Assay		P	From MGI
	GO:0001666	response to hypoxia	MGI:MGI:4417868	ISO: Inferred from Sequence Orthology	UniProtKB:Q62976	P	From MGI
	GO:0001666	response to hypoxia	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:Q12791	P	From MGI
	GO:0003779	actin binding	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:Q12791	F	From MGI
	GO:0005216	ion channel activity	MGI:MGI:1354194	IEA: Inferred from Electronic Annotation	UniProtKB-KW:KW-0407	F	From MGI
	GO:0005216	ion channel activity	MGI:MGI:2152098	IEA: Inferred from Electronic Annotation	InterPro:IPR005821	F	From MGI
	GO:0005244	voltage-gated ion channel activity	MGI:MGI:1354194	IEA: Inferred from Electronic Annotation	UniProtKB-KW:KW-0851	F	From MGI
	GO:0005249	voltage-gated potassium channel activity	MGI:MGI:3053479 PMID:15184377^[2]	IMP: Inferred from Mutant Phenotype	MGI:MGI:3053849	F	From MGI
	GO:0005249	voltage-gated potassium channel activity	MGI:MGI:3607626 PMID:16081418^[3]	IDA: Inferred from Direct Assay		F	From MGI
	GO:0005249	voltage-gated potassium channel activity	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:Q12791	F	From MGI
	GO:0005249	voltage-gated potassium channel activity	MGI:MGI:61591 PMID:7687074^[4]	IDA: Inferred from Direct Assay		F	From MGI
	GO:0005267	potassium channel activity	MGI:MGI:3695228 PMID:16873365^[5]	IGI: Inferred from Genetic Interaction	MGI:MGI:1277957	F	From MGI
	GO:0005267	potassium channel activity	MGI:MGI:3697763 PMID:17135251^[6]	IMP: Inferred from Mutant Phenotype	MGI:MGI:3053849	F	From MGI
	GO:0005515	protein binding	MGI:MGI:3852248 PMID:19423573^[7]	IPI: Inferred from Physical Interaction	UniProtKB:O88952 UniProtKB:P16858 UniProtKB:P27573 UniProtKB:P48036 UniProtKB:P61982 UniProtKB:P62204 UniProtKB:P63260 UniProtKB:P84075 UniProtKB:Q00623	F	From MGI
	GO:0005783	endoplasmic reticulum	MGI:MGI:3700594 PMID:17303127^[8]	IDA: Inferred from Direct Assay		C	From MGI
	GO:0005886	plasma membrane	MGI:MGI:1346192 PMID:10517674^[9]	IDA: Inferred from Direct Assay		C	From MGI
	GO:0005886	plasma membrane	MGI:MGI:2680842 PMID:12952984^[10]	IDA: Inferred from Direct Assay		C	From MGI
	GO:0005886	plasma membrane	MGI:MGI:4417868	ISO: Inferred from Sequence Orthology	UniProtKB:Q62976	C	From MGI
	GO:0005901	caveola	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:Q12791	C	From MGI
	GO:0006810	transport	MGI:MGI:1354194	IEA: Inferred from Electronic Annotation	UniProtKB-KW:KW-0813	P	From MGI
	GO:0006811	ion transport	MGI:MGI:1354194	IEA: Inferred from Electronic Annotation	UniProtKB-KW:KW-0406	P	From MGI
	GO:0006811	ion transport	MGI:MGI:2152098	IEA: Inferred from Electronic Annotation	InterPro:IPR005821	P	From MGI
	GO:0006813	potassium ion transport	MGI:MGI:1346192 PMID:10517674^[9]	IDA: Inferred from Direct Assay		P	From MGI
	GO:0006813	potassium ion transport	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:Q12791	P	From MGI
	GO:0006813	potassium ion transport	MGI:MGI:61591 PMID:7687074^[4]	IDA: Inferred from Direct Assay		P	From MGI
	GO:0006970	response to osmotic stress	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:Q12791	P	From MGI
	GO:0007268	synaptic transmission	MGI:MGI:3047034 PMID:15194823^[11]	IMP: Inferred from Mutant Phenotype	MGI:MGI:3050114	P	From MGI
	GO:0007605	sensory perception of sound	MGI:MGI:3052624 PMID:15328414^[12]	IMP: Inferred from Mutant Phenotype	MGI:MGI:3050114	P	From MGI
	GO:0007605	sensory perception of sound	MGI:MGI:3626129 PMID:16763026^[13]	IMP: Inferred from Mutant Phenotype	MGI:MGI:3050114	P	From MGI
	GO:0007623	circadian rhythm	MGI:MGI:3654773 PMID:16845385^[14]	IMP: Inferred from Mutant Phenotype	MGI:MGI:3053849	P	From MGI
	GO:0007628	adult walking behavior	MGI:MGI:3047034 PMID:15194823^[11]	IMP: Inferred from Mutant Phenotype	MGI:MGI:3050114	P	From MGI
	GO:0007628	adult walking behavior	MGI:MGI:3053479 PMID:15184377^[2]	IMP: Inferred from Mutant Phenotype	MGI:MGI:3053849	P	From MGI
	GO:0008076	voltage-gated potassium channel complex	MGI:MGI:2450799 PMID:12388098^[15]	IGI: Inferred from Genetic Interaction	MGI:MGI:1913272 MGI:MGI:1334203	C	From MGI
	GO:0008076	voltage-gated potassium channel complex	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:Q12791	C	From MGI
	GO:0009268	response to pH	MGI:MGI:4417868	ISO: Inferred from Sequence Orthology	UniProtKB:Q62976	P	From MGI
	GO:0009897	external side of plasma membrane	MGI:MGI:3700594 PMID:17303127^[8]	IDA: Inferred from Direct Assay		C	From MGI
	GO:0009897	external side of plasma membrane	MGI:MGI:4417868	ISO: Inferred from Sequence Orthology	UniProtKB:Q62976	C	From MGI
	GO:0015269	calcium-activated potassium channel activity	MGI:MGI:1346192 PMID:10517674^[9]	IDA: Inferred from Direct Assay		F	From MGI
	GO:0015269	calcium-activated potassium channel activity	MGI:MGI:2450799 PMID:12388098^[15]	IGI: Inferred from Genetic Interaction	MGI:MGI:1334203 MGI:MGI:1913272	F	From MGI
	GO:0015269	calcium-activated potassium channel activity	MGI:MGI:3053479 PMID:15184377^[2]	IMP: Inferred from Mutant Phenotype	MGI:MGI:3053849	F	From MGI
	GO:0015269	calcium-activated potassium channel activity	MGI:MGI:3607626 PMID:16081418^[3]	IDA: Inferred from Direct Assay		F	From MGI
	GO:0015269	calcium-activated potassium channel activity	MGI:MGI:3611743 PMID:16306267^[1]	IDA: Inferred from Direct Assay		F	From MGI
	GO:0015269	calcium-activated potassium channel activity	MGI:MGI:3700594 PMID:17303127^[8]	IDA: Inferred from Direct Assay		F	From MGI
	GO:0015269	calcium-activated potassium channel activity	MGI:MGI:4417868	ISO: Inferred from Sequence Orthology	UniProtKB:Q62976	F	From MGI
	GO:0015269	calcium-activated potassium channel activity	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:Q12791	F	From MGI
	GO:0015269	calcium-activated potassium channel activity	MGI:MGI:61591 PMID:7687074^[4]	IDA: Inferred from Direct Assay		F	From MGI
	GO:0016020	membrane	MGI:MGI:1354194	IEA: Inferred from Electronic Annotation	UniProtKB-KW:KW-0472	C	From MGI
	GO:0016020	membrane	MGI:MGI:2152098	IEA: Inferred from Electronic Annotation	InterPro:IPR005821 InterPro:IPR003929	C	From MGI
	GO:0016021	integral to membrane	MGI:MGI:2450799 PMID:12388098^[15]	IDA: Inferred from Direct Assay		C	From MGI
	GO:0016021	integral to membrane	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:Q12791	C	From MGI
	GO:0016021	integral to membrane	MGI:MGI:61591 PMID:7687074^[4]	IC: Inferred by Curator	GO:0015269	C	From MGI
	GO:0016324	apical plasma membrane	MGI:MGI:3697763 PMID:17135251^[6]	IDA: Inferred from Direct Assay		C	From MGI
	GO:0016324	apical plasma membrane	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:Q12791	C	From MGI
	GO:0019228	regulation of action potential in neuron	MGI:MGI:3654773 PMID:16845385^[14]	IMP: Inferred from Mutant Phenotype	MGI:MGI:3053849	P	From MGI
	GO:0030007	cellular potassium ion homeostasis	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:Q12791	P	From MGI
	GO:0030425	dendrite	MGI:MGI:4417868	ISO: Inferred from Sequence Orthology	UniProtKB:Q62976	C	From MGI
	GO:0031960	response to corticosteroid stimulus	MGI:MGI:4417868	ISO: Inferred from Sequence Orthology	UniProtKB:Q62976	P	From MGI
	GO:0032344	regulation of aldosterone metabolic process	MGI:MGI:3693138 PMID:17122062^[16]	IMP: Inferred from Mutant Phenotype	MGI:MGI:3050114	P	From MGI
	GO:0032403	protein complex binding	MGI:MGI:4417868	ISO: Inferred from Sequence Orthology	UniProtKB:Q62976	F	From MGI
	GO:0034220	ion transmembrane transport	MGI:MGI:1354194	IEA: Inferred from Electronic Annotation	UniProtKB-KW:KW-0407	P	From MGI
	GO:0034220	ion transmembrane transport	MGI:MGI:2152098	IEA: Inferred from Electronic Annotation	InterPro:IPR005821	P	From MGI
	GO:0034465	response to carbon monoxide	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:Q12791	P	From MGI
	GO:0034765	regulation of ion transmembrane transport	MGI:MGI:1354194	IEA: Inferred from Electronic Annotation	UniProtKB-KW:KW-0851	P	From MGI
	GO:0034765	regulation of ion transmembrane transport	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:Q12791	P	From MGI
	GO:0042311	vasodilation	MGI:MGI:3695011 PMID:15867178^[17]	IMP: Inferred from Mutant Phenotype	MGI:MGI:3050114	P	From MGI
	GO:0042312	regulation of vasodilation	MGI:MGI:4417868	ISO: Inferred from Sequence Orthology	UniProtKB:Q62976	P	From MGI
	GO:0042391	regulation of membrane potential	MGI:MGI:3047034 PMID:15194823^[11]	IMP: Inferred from Mutant Phenotype	MGI:MGI:3050114	P	From MGI
	GO:0042391	regulation of membrane potential	MGI:MGI:3626129 PMID:16763026^[13]	IMP: Inferred from Mutant Phenotype	MGI:MGI:3050114	P	From MGI
	GO:0042391	regulation of membrane potential	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:Q12791	P	From MGI
	GO:0042391	regulation of membrane potential	MGI:MGI:61591 PMID:7687074^[4]	IDA: Inferred from Direct Assay		P	From MGI
	GO:0042491	auditory receptor cell differentiation	MGI:MGI:3052624 PMID:15328414^[12]	IMP: Inferred from Mutant Phenotype	MGI:MGI:3050114	P	From MGI
	GO:0042491	auditory receptor cell differentiation	MGI:MGI:3697555 PMID:17074442^[18]	IMP: Inferred from Mutant Phenotype	MGI:MGI:3050114	P	From MGI
	GO:0042803	protein homodimerization activity	MGI:MGI:4417868	ISO: Inferred from Sequence Orthology	UniProtKB:Q62976	F	From MGI
	GO:0043025	neuronal cell body	MGI:MGI:4417868	ISO: Inferred from Sequence Orthology	UniProtKB:Q62976	C	From MGI
	GO:0043065	positive regulation of apoptotic process	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:Q12791	P	From MGI
	GO:0043195	terminal button	MGI:MGI:3052624 PMID:15328414^[12]	IDA: Inferred from Direct Assay		C	From MGI
	GO:0043627	response to estrogen stimulus	MGI:MGI:4417868	ISO: Inferred from Sequence Orthology	UniProtKB:Q62976	P	From MGI
	GO:0044444	cytoplasmic part	MGI:MGI:2680842 PMID:12952984^[10]	IDA: Inferred from Direct Assay		C	From MGI
	GO:0045211	postsynaptic membrane	MGI:MGI:3052624 PMID:15328414^[12]	IDA: Inferred from Direct Assay		C	From MGI
	GO:0045475	locomotor rhythm	MGI:MGI:3654773 PMID:16845385^[14]	IMP: Inferred from Mutant Phenotype	MGI:MGI:3053849	P	From MGI
	GO:0045794	negative regulation of cell volume	MGI:MGI:3695228 PMID:16873365^[5]	IMP: Inferred from Mutant Phenotype	MGI:MGI:3053849	P	From MGI
	GO:0045794	negative regulation of cell volume	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:Q12791	P	From MGI
	GO:0046541	saliva secretion	MGI:MGI:3695228 PMID:16873365^[5]	IGI: Inferred from Genetic Interaction	MGI:MGI:1277957	P	From MGI
	GO:0046872	metal ion binding	MGI:MGI:1354194	IEA: Inferred from Electronic Annotation	UniProtKB-KW:KW-0479	F	From MGI
	GO:0048469	cell maturation	MGI:MGI:3052624 PMID:15328414^[12]	IMP: Inferred from Mutant Phenotype	MGI:MGI:3050114	P	From MGI
	GO:0048471	perinuclear region of cytoplasm	MGI:MGI:4417868	ISO: Inferred from Sequence Orthology	UniProtKB:Q62976	C	From MGI
	GO:0048787	presynaptic active zone membrane	MGI:MGI:4417868	ISO: Inferred from Sequence Orthology	UniProtKB:Q62976	C	From MGI
	GO:0050885	neuromuscular process controlling balance	MGI:MGI:3047034 PMID:15194823^[11]	IMP: Inferred from Mutant Phenotype	MGI:MGI:3050114	P	From MGI
	GO:0050885	neuromuscular process controlling balance	MGI:MGI:3053479 PMID:15184377^[2]	IMP: Inferred from Mutant Phenotype	MGI:MGI:3053849	P	From MGI
	GO:0051260	protein homooligomerization	MGI:MGI:3700594 PMID:17303127^[8]	IDA: Inferred from Direct Assay		P	From MGI
	GO:0051289	protein homotetramerization	MGI:MGI:4417868	ISO: Inferred from Sequence Orthology	UniProtKB:Q62976	P	From MGI
	GO:0051592	response to calcium ion	MGI:MGI:4417868	ISO: Inferred from Sequence Orthology	UniProtKB:Q62976	P	From MGI
	GO:0051592	response to calcium ion	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:Q12791	P	From MGI
	GO:0055085	transmembrane transport	MGI:MGI:2152098	IEA: Inferred from Electronic Annotation	InterPro:IPR005821	P	From MGI
	GO:0060072	large conductance calcium-activated potassium channel activity	MGI:MGI:2450799 PMID:12388098^[15]	IDA: Inferred from Direct Assay		F	From MGI
	GO:0060072	large conductance calcium-activated potassium channel activity	MGI:MGI:3695228 PMID:16873365^[5]	IMP: Inferred from Mutant Phenotype	MGI:MGI:3053849	F	From MGI
	GO:0060072	large conductance calcium-activated potassium channel activity	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:Q12791	F	From MGI
	GO:0060073	micturition	MGI:MGI:3053479 PMID:15184377^[2]	IMP: Inferred from Mutant Phenotype	MGI:MGI:3053849	P	From MGI
	GO:0060073	micturition	MGI:MGI:3053479 PMID:15184377^[2]	IMP: Inferred from Mutant Phenotype	MGI:MGI:3053849	P	From MGI
	GO:0060073	micturition	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:Q12791	P	From MGI
	GO:0060082	eye blink reflex	MGI:MGI:3047034 PMID:15194823^[11]	IMP: Inferred from Mutant Phenotype	MGI:MGI:3050114	P	From MGI
	GO:0060083	smooth muscle contraction involved in micturition	MGI:MGI:3612609 PMID:15827347^[19]	IMP: Inferred from Mutant Phenotype	MGI:MGI:3053849	P	From MGI
	GO:0060083	smooth muscle contraction involved in micturition	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:Q12791	P	From MGI
	GO:0060087	relaxation of vascular smooth muscle	MGI:MGI:3695011 PMID:15867178^[17]	IMP: Inferred from Mutant Phenotype	MGI:MGI:3050114	P	From MGI
	GO:0071805	potassium ion transmembrane transport	MGI:MGI:1346192 PMID:10517674^[9]	IDA: Inferred from Direct Assay		P	From MGI
	GO:0071805	potassium ion transmembrane transport	MGI:MGI:2450799 PMID:12388098^[15]	IDA: Inferred from Direct Assay		P	From MGI
	GO:0071805	potassium ion transmembrane transport	MGI:MGI:2450799 PMID:12388098^[15]	IGI: Inferred from Genetic Interaction	MGI:MGI:1334203 MGI:MGI:1913272	P	From MGI
	GO:0071805	potassium ion transmembrane transport	MGI:MGI:3053479 PMID:15184377^[2]	IMP: Inferred from Mutant Phenotype	MGI:MGI:3053849	P	From MGI
	GO:0071805	potassium ion transmembrane transport	MGI:MGI:3607626 PMID:16081418^[3]	IDA: Inferred from Direct Assay		P	From MGI
	GO:0071805	potassium ion transmembrane transport	MGI:MGI:3611743 PMID:16306267^[1]	IDA: Inferred from Direct Assay		P	From MGI
	GO:0071805	potassium ion transmembrane transport	MGI:MGI:3695228 PMID:16873365^[5]	IGI: Inferred from Genetic Interaction	MGI:MGI:1277957	P	From MGI
	GO:0071805	potassium ion transmembrane transport	MGI:MGI:3695228 PMID:16873365^[5]	IMP: Inferred from Mutant Phenotype	MGI:MGI:3053849	P	From MGI
	GO:0071805	potassium ion transmembrane transport	MGI:MGI:3697763 PMID:17135251^[6]	IMP: Inferred from Mutant Phenotype	MGI:MGI:3053849	P	From MGI
	GO:0071805	potassium ion transmembrane transport	MGI:MGI:3700594 PMID:17303127^[8]	IDA: Inferred from Direct Assay		P	From MGI
	GO:0071805	potassium ion transmembrane transport	MGI:MGI:4417868	ISO: Inferred from Sequence Orthology	UniProtKB:O88660	P	From MGI
	GO:0071805	potassium ion transmembrane transport	MGI:MGI:4459044		PANTHER:PTHR10027	P	From MGI
	GO:0071805	potassium ion transmembrane transport	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:Q12791	P	From MGI
	GO:0071805	potassium ion transmembrane transport	MGI:MGI:61591 PMID:7687074^[4]	IDA: Inferred from Direct Assay		P	From MGI
NOT	GO:0007605	sensory perception of sound	MGI:MGI:3697763 PMID:17135251^[6]	IMP: Inferred from Mutant Phenotype	MGI:MGI:3053849	P	From MGI
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 ^1.2 McCartney CE et al. (2005) A cysteine-rich motif confers hypoxia sensitivity to mammalian large conductance voltage- and Ca-activated K (BK) channel alpha-subunits. Proc Natl Acad Sci U S A 102: 17870-6 PubMed GONUTS page
↑ ^2.0 ^2.1 ^2.2 ^2.3 ^2.4 ^2.5 ^2.6 Meredith AL et al. (2004) Overactive bladder and incontinence in the absence of the BK large conductance Ca2+-activated K+ channel. J Biol Chem 279: 36746-52 PubMed GONUTS page
↑ ^3.0 ^3.1 ^3.2 Chen L et al. (2005) Functionally diverse complement of large conductance calcium- and voltage-activated potassium channel (BK) alpha-subunits generated from a single site of splicing. J Biol Chem 280: 33599-609 PubMed GONUTS page
↑ ^4.0 ^4.1 ^4.2 ^4.3 ^4.4 ^4.5 Butler A et al. (1993) mSlo, a complex mouse gene encoding "maxi" calcium-activated potassium channels. Science 261: 221-4 PubMed GONUTS page
↑ ^5.0 ^5.1 ^5.2 ^5.3 ^5.4 ^5.5 Romanenko V et al. (2006) Molecular identification and physiological roles of parotid acinar cell maxi-K channels. J Biol Chem 281: 27964-72 PubMed GONUTS page
↑ ^6.0 ^6.1 ^6.2 ^6.3 Pyott SJ et al. (2007) Cochlear function in mice lacking the BK channel alpha, beta1, or beta4 subunits. J Biol Chem 282: 3312-24 PubMed GONUTS page
↑ Kathiresan T et al. (2009) A protein interaction network for the large conductance Ca(2+)-activated K(+) channel in the mouse cochlea. Mol Cell Proteomics 8: 1972-87 PubMed GONUTS page
↑ ^8.0 ^8.1 ^8.2 ^8.3 ^8.4 Ma D et al. (2007) Differential trafficking of carboxyl isoforms of Ca2+-gated (Slo1) potassium channels. FEBS Lett 581: 1000-8 PubMed GONUTS page
↑ ^9.0 ^9.1 ^9.2 ^9.3 Shipston MJ et al. (1999) Molecular components of large conductance calcium-activated potassium (BK) channels in mouse pituitary corticotropes. Mol Endocrinol 13: 1728-37 PubMed GONUTS page
↑ ^10.0 ^10.1 Eghbali M et al. (2003) Diminished surface clustering and increased perinuclear accumulation of large conductance Ca2+-activated K+ channel in mouse myometrium with pregnancy. J Biol Chem 278: 45311-7 PubMed GONUTS page
↑ ^11.0 ^11.1 ^11.2 ^11.3 ^11.4 Sausbier M et al. (2004) Cerebellar ataxia and Purkinje cell dysfunction caused by Ca2+-activated K+ channel deficiency. Proc Natl Acad Sci U S A 101: 9474-8 PubMed GONUTS page
↑ ^12.0 ^12.1 ^12.2 ^12.3 ^12.4 Rüttiger L et al. (2004) Deletion of the Ca2+-activated potassium (BK) alpha-subunit but not the BKbeta1-subunit leads to progressive hearing loss. Proc Natl Acad Sci U S A 101: 12922-7 PubMed GONUTS page
↑ ^13.0 ^13.1 Oliver D et al. (2006) The role of BKCa channels in electrical signal encoding in the mammalian auditory periphery. J Neurosci 26: 6181-9 PubMed GONUTS page
↑ ^14.0 ^14.1 ^14.2 Meredith AL et al. (2006) BK calcium-activated potassium channels regulate circadian behavioral rhythms and pacemaker output. Nat Neurosci 9: 1041-9 PubMed GONUTS page
↑ ^15.0 ^15.1 ^15.2 ^15.3 ^15.4 ^15.5 Nehrke K et al. (2003) Molecular identification of Ca2+-activated K+ channels in parotid acinar cells. Am J Physiol Cell Physiol 284: C535-46 PubMed GONUTS page
↑ Nagai T et al. (2006) The rewards of nicotine: regulation by tissue plasminogen activator-plasmin system through protease activated receptor-1. J Neurosci 26: 12374-83 PubMed GONUTS page
↑ ^17.0 ^17.1 Sausbier M et al. (2005) Elevated blood pressure linked to primary hyperaldosteronism and impaired vasodilation in BK channel-deficient mice. Circulation 112: 60-8 PubMed GONUTS page
↑ Engel J et al. (2006) Two classes of outer hair cells along the tonotopic axis of the cochlea. Neuroscience 143: 837-49 PubMed GONUTS page
↑ Thorneloe KS et al. (2005) Urodynamic properties and neurotransmitter dependence of urinary bladder contractility in the BK channel deletion model of overactive bladder. Am J Physiol Renal Physiol 289: F604-10 PubMed GONUTS page

[PMID:16306267-0] 1.0 ^1.1 ^1.2 McCartney CE et al. (2005) A cysteine-rich motif confers hypoxia sensitivity to mammalian large conductance voltage- and Ca-activated K (BK) channel alpha-subunits. Proc Natl Acad Sci U S A 102: 17870-6 PubMed GONUTS page

[PMID:15184377-1] 2.0 ^2.1 ^2.2 ^2.3 ^2.4 ^2.5 ^2.6 Meredith AL et al. (2004) Overactive bladder and incontinence in the absence of the BK large conductance Ca2+-activated K+ channel. J Biol Chem 279: 36746-52 PubMed GONUTS page

[PMID:16081418-2] 3.0 ^3.1 ^3.2 Chen L et al. (2005) Functionally diverse complement of large conductance calcium- and voltage-activated potassium channel (BK) alpha-subunits generated from a single site of splicing. J Biol Chem 280: 33599-609 PubMed GONUTS page

[PMID:7687074-3] 4.0 ^4.1 ^4.2 ^4.3 ^4.4 ^4.5 Butler A et al. (1993) mSlo, a complex mouse gene encoding "maxi" calcium-activated potassium channels. Science 261: 221-4 PubMed GONUTS page

[PMID:16873365-4] 5.0 ^5.1 ^5.2 ^5.3 ^5.4 ^5.5 Romanenko V et al. (2006) Molecular identification and physiological roles of parotid acinar cell maxi-K channels. J Biol Chem 281: 27964-72 PubMed GONUTS page

[PMID:17135251-5] 6.0 ^6.1 ^6.2 ^6.3 Pyott SJ et al. (2007) Cochlear function in mice lacking the BK channel alpha, beta1, or beta4 subunits. J Biol Chem 282: 3312-24 PubMed GONUTS page

[PMID:19423573-6] Kathiresan T et al. (2009) A protein interaction network for the large conductance Ca(2+)-activated K(+) channel in the mouse cochlea. Mol Cell Proteomics 8: 1972-87 PubMed GONUTS page

[PMID:17303127-7] 8.0 ^8.1 ^8.2 ^8.3 ^8.4 Ma D et al. (2007) Differential trafficking of carboxyl isoforms of Ca2+-gated (Slo1) potassium channels. FEBS Lett 581: 1000-8 PubMed GONUTS page

[PMID:10517674-8] 9.0 ^9.1 ^9.2 ^9.3 Shipston MJ et al. (1999) Molecular components of large conductance calcium-activated potassium (BK) channels in mouse pituitary corticotropes. Mol Endocrinol 13: 1728-37 PubMed GONUTS page

[PMID:12952984-9] 10.0 ^10.1 Eghbali M et al. (2003) Diminished surface clustering and increased perinuclear accumulation of large conductance Ca2+-activated K+ channel in mouse myometrium with pregnancy. J Biol Chem 278: 45311-7 PubMed GONUTS page

[PMID:15194823-10] 11.0 ^11.1 ^11.2 ^11.3 ^11.4 Sausbier M et al. (2004) Cerebellar ataxia and Purkinje cell dysfunction caused by Ca2+-activated K+ channel deficiency. Proc Natl Acad Sci U S A 101: 9474-8 PubMed GONUTS page

[PMID:15328414-11] 12.0 ^12.1 ^12.2 ^12.3 ^12.4 Rüttiger L et al. (2004) Deletion of the Ca2+-activated potassium (BK) alpha-subunit but not the BKbeta1-subunit leads to progressive hearing loss. Proc Natl Acad Sci U S A 101: 12922-7 PubMed GONUTS page

[PMID:16763026-12] 13.0 ^13.1 Oliver D et al. (2006) The role of BKCa channels in electrical signal encoding in the mammalian auditory periphery. J Neurosci 26: 6181-9 PubMed GONUTS page

[PMID:16845385-13] 14.0 ^14.1 ^14.2 Meredith AL et al. (2006) BK calcium-activated potassium channels regulate circadian behavioral rhythms and pacemaker output. Nat Neurosci 9: 1041-9 PubMed GONUTS page

[PMID:12388098-14] 15.0 ^15.1 ^15.2 ^15.3 ^15.4 ^15.5 Nehrke K et al. (2003) Molecular identification of Ca2+-activated K+ channels in parotid acinar cells. Am J Physiol Cell Physiol 284: C535-46 PubMed GONUTS page

[PMID:17122062-15] Nagai T et al. (2006) The rewards of nicotine: regulation by tissue plasminogen activator-plasmin system through protease activated receptor-1. J Neurosci 26: 12374-83 PubMed GONUTS page

[PMID:15867178-16] 17.0 ^17.1 Sausbier M et al. (2005) Elevated blood pressure linked to primary hyperaldosteronism and impaired vasodilation in BK channel-deficient mice. Circulation 112: 60-8 PubMed GONUTS page

[PMID:17074442-17] Engel J et al. (2006) Two classes of outer hair cells along the tonotopic axis of the cochlea. Neuroscience 143: 837-49 PubMed GONUTS page

[PMID:15827347-18] Thorneloe KS et al. (2005) Urodynamic properties and neurotransmitter dependence of urinary bladder contractility in the BK channel deletion model of overactive bladder. Am J Physiol Renal Physiol 289: F604-10 PubMed GONUTS page

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Species (Taxon ID)	Mus musculus (house mouse) (taxon:10090)
Gene Name(s)	Kcnma1 ( synonyms: BK channel alpha subunit, BKCa, MaxiK, mSlo1, Slo, Slo1 )
Protein Name(s)	potassium large conductance calcium-activated channel, subfamily M, alpha member 1,
External Links
MGI	MGI:99923

MGI:Kcnma1

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