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MGI:Kat2b
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Kat2b ( synonyms: Pcaf ) | |
| Protein Name(s) | K(lysine) acetyltransferase 2B, | |
| External Links | ||
| MGI | MGI:1343094 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000123 |
histone acetyltransferase complex |
MGI:MGI:1344193 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0000776 |
kinetochore |
MGI:MGI:2682084 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0003712 |
transcription cofactor activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0003713 |
transcription coactivator activity |
MGI:MGI:3513590 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0003713 |
transcription coactivator activity |
MGI:MGI:3576958 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0003713 |
transcription coactivator activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0004402 |
histone acetyltransferase activity |
MGI:MGI:1344193 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0004402 |
histone acetyltransferase activity |
MGI:MGI:3582105 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0004468 |
lysine N-acetyltransferase activity |
MGI:MGI:3793386 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0004468 |
lysine N-acetyltransferase activity |
MGI:MGI:4410401 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0004468 |
lysine N-acetyltransferase activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0004861 |
cyclin-dependent protein kinase inhibitor activity |
MGI:MGI:4410401 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:1344193 |
IPI: Inferred from Physical Interaction |
UniProtKB:P45481 |
F |
From MGI |
||
| GO:0005515 |
protein binding |
MGI:MGI:3513590 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3525929 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3576958 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:3513590 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:3793386 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:4410401 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005671 |
Ada2/Gcn5/Ada3 transcription activator complex |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0006351 |
transcription, DNA-dependent |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0804 |
P |
From MGI |
||
| GO:0006355 |
regulation of transcription, DNA-dependent |
MGI:MGI:1354836 |
TAS: Traceable Author Statement |
P |
From MGI |
|||
| GO:0006473 |
protein acetylation |
MGI:MGI:1354836 |
TAS: Traceable Author Statement |
P |
From MGI |
|||
| GO:0007049 |
cell cycle |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0131 |
P |
From MGI |
||
| GO:0008080 |
N-acetyltransferase activity |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0008134 |
transcription factor binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0008285 |
negative regulation of cell proliferation |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0016407 |
acetyltransferase activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0016573 |
histone acetylation |
MGI:MGI:3582105 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0016585 |
chromatin remodeling complex |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0016740 |
transferase activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0808 |
F |
From MGI |
||
| GO:0016746 |
transferase activity, transferring acyl groups |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0012 |
F |
From MGI |
||
| GO:0018076 |
N-terminal peptidyl-lysine acetylation |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0018393 |
internal peptidyl-lysine acetylation |
MGI:MGI:4410401 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0018394 |
peptidyl-lysine acetylation |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0019901 |
protein kinase binding |
MGI:MGI:4410401 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0031672 |
A band |
MGI:MGI:3793386 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0031674 |
I band |
MGI:MGI:3793386 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0032869 |
cellular response to insulin stimulus |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0042641 |
actomyosin |
MGI:MGI:3793386 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0042826 |
histone deacetylase binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0043966 |
histone H3 acetylation |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0045736 |
negative regulation of cyclin-dependent protein kinase activity |
MGI:MGI:4410401 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0045893 |
positive regulation of transcription, DNA-dependent |
MGI:MGI:3513590 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0045893 |
positive regulation of transcription, DNA-dependent |
MGI:MGI:3576958 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0045944 |
positive regulation of transcription from RNA polymerase II promoter |
MGI:MGI:3525929 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:2137495 |
P |
From MGI |
||
| GO:2001141 |
regulation of RNA biosynthetic process |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 Xu W et al. (1998) Mammalian GCN5 and P/CAF acetyltransferases have homologous amino-terminal domains important for recognition of nucleosomal substrates. Mol Cell Biol 18: 5659-69 PubMed GONUTS page
- ↑ Craig JM et al. (2003) Analysis of mammalian proteins involved in chromatin modification reveals new metaphase centromeric proteins and distinct chromosomal distribution patterns. Hum Mol Genet 12: 3109-21 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 Barbacci E et al. (2004) HNF1beta/TCF2 mutations impair transactivation potential through altered co-regulator recruitment. Hum Mol Genet 13: 3139-49 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 Hiesberger T et al. (2005) Role of the hepatocyte nuclear factor-1beta (HNF-1beta) C-terminal domain in Pkhd1 (ARPKD) gene transcription and renal cystogenesis. J Biol Chem 280: 10578-86 PubMed GONUTS page
- ↑ 5.0 5.1 Jakkaraju S et al. (2005) TIPs are tension-responsive proteins involved in myogenic versus adipogenic differentiation. Dev Cell 9: 39-49 PubMed GONUTS page
- ↑ 6.0 6.1 6.2 6.3 6.4 Gupta MP et al. (2008) HDAC4 and PCAF bind to cardiac sarcomeres and play a role in regulating myofilament contractile activity. J Biol Chem 283: 10135-46 PubMed GONUTS page
- ↑ 7.0 7.1 7.2 7.3 7.4 7.5 Mateo F et al. (2009) The transcriptional co-activator PCAF regulates cdk2 activity. Nucleic Acids Res 37: 7072-84 PubMed GONUTS page
- ↑ 8.0 8.1 Cao D et al. (2005) Modulation of smooth muscle gene expression by association of histone acetyltransferases and deacetylases with myocardin. Mol Cell Biol 25: 364-76 PubMed GONUTS page
- ↑ 9.0 9.1 Schiltz RL & Nakatani Y (2000) The PCAF acetylase complex as a potential tumor suppressor. Biochim Biophys Acta 1470: M37-53 PubMed GONUTS page
