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MGI:Jmjd6
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Jmjd6 ( synonyms: PSR, PtdSerR, Ptdsr ) | |
| Protein Name(s) | jumonji domain containing 6, | |
| External Links | ||
| MGI | MGI:1858910 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0001568 |
blood vessel development |
MGI:MGI:3606737 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3580706 |
P |
From MGI |
||
| GO:0001822 |
kidney development |
MGI:MGI:3580691 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3580706 |
P |
From MGI |
||
| GO:0002040 |
sprouting angiogenesis |
MGI:MGI:4940413 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0003723 |
RNA binding |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0694 |
F |
From MGI |
||
| GO:0003727 |
single-stranded RNA binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0004872 |
receptor activity |
MGI:MGI:1855743 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0005506 |
iron ion binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:4940413 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:3027657 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005654 |
nucleoplasm |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005730 |
nucleolus |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005886 |
plasma membrane |
MGI:MGI:1855743 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005886 |
plasma membrane |
MGI:MGI:3618422 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0006351 |
transcription, DNA-dependent |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0804 |
P |
From MGI |
||
| GO:0006355 |
regulation of transcription, DNA-dependent |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0805 |
P |
From MGI |
||
| GO:0006397 |
mRNA processing |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0507 |
P |
From MGI |
||
| GO:0006915 |
apoptotic process |
MGI:MGI:1855743 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0007166 |
cell surface receptor signaling pathway |
MGI:MGI:1855743 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0007275 |
multicellular organismal development |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0217 |
P |
From MGI |
||
| GO:0007507 |
heart development |
MGI:MGI:3606737 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3580706 |
P |
From MGI |
||
| GO:0008380 |
RNA splicing |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0508 |
P |
From MGI |
||
| GO:0016491 |
oxidoreductase activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0560 |
F |
From MGI |
||
| GO:0016568 |
chromatin modification |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0156 |
P |
From MGI |
||
| GO:0016702 |
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0223 |
F |
From MGI |
||
| GO:0018395 |
peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0030154 |
cell differentiation |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0221 |
P |
From MGI |
||
| GO:0030324 |
lung development |
MGI:MGI:2682078 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2686850 |
P |
From MGI |
||
| GO:0030324 |
lung development |
MGI:MGI:3580691 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3580706 |
P |
From MGI |
||
| GO:0033077 |
T cell differentiation in thymus |
MGI:MGI:3042820 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3043930 |
P |
From MGI |
||
| GO:0033746 |
histone demethylase activity (H3-R2 specific) |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0033749 |
histone demethylase activity (H4-R3 specific) |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0042116 |
macrophage activation |
MGI:MGI:3580691 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3580706 |
P |
From MGI |
||
| GO:0042802 |
identical protein binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0043277 |
apoptotic cell clearance |
MGI:MGI:3042820 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3043930 |
P |
From MGI |
||
| GO:0043277 |
apoptotic cell clearance |
MGI:MGI:3618422 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0043654 |
recognition of apoptotic cell |
MGI:MGI:2682078 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2686850 |
P |
From MGI |
||
| GO:0046872 |
metal ion binding |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0479 |
F |
From MGI |
||
| GO:0048024 |
regulation of nuclear mRNA splicing, via spliceosome |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0048024 |
regulation of nuclear mRNA splicing, via spliceosome |
MGI:MGI:4940413 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0048821 |
erythrocyte development |
MGI:MGI:3042820 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3043930 |
P |
From MGI |
||
| GO:0048821 |
erythrocyte development |
MGI:MGI:3580691 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3580706 |
P |
From MGI |
||
| GO:0060041 |
retina development in camera-type eye |
MGI:MGI:3580691 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3580706 |
P |
From MGI |
||
| GO:0070078 |
histone H3-R2 demethylation |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0070079 |
histone H4-R3 demethylation |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0070815 |
peptidyl-lysine 5-dioxygenase activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
|
NOT |
GO:0043277 |
apoptotic cell clearance |
MGI:MGI:3580691 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3580706 |
P |
From MGI |
|
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Schneider JE et al. (2004) Identification of cardiac malformations in mice lacking Ptdsr using a novel high-throughput magnetic resonance imaging technique. BMC Dev Biol 4: 16 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 2.4 2.5 Böse J et al. (2004) The phosphatidylserine receptor has essential functions during embryogenesis but not in apoptotic cell removal. J Biol 3: 15 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 Boeckel JN et al. (2011) Jumonji domain-containing protein 6 (Jmjd6) is required for angiogenic sprouting and regulates splicing of VEGF-receptor 1. Proc Natl Acad Sci U S A 108: 3276-81 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 4.3 Fadok VA et al. (2000) A receptor for phosphatidylserine-specific clearance of apoptotic cells. Nature 405: 85-90 PubMed GONUTS page
- ↑ Cui P et al. (2004) Nuclear localization of the phosphatidylserine receptor protein via multiple nuclear localization signals. Exp Cell Res 293: 154-63 PubMed GONUTS page
- ↑ 6.0 6.1 Monks J et al. (2005) Epithelial cells as phagocytes: apoptotic epithelial cells are engulfed by mammary alveolar epithelial cells and repress inflammatory mediator release. Cell Death Differ 12: 107-14 PubMed GONUTS page
- ↑ 7.0 7.1 Li MO et al. (2003) Phosphatidylserine receptor is required for clearance of apoptotic cells. Science 302: 1560-3 PubMed GONUTS page
- ↑ 8.0 8.1 8.2 Kunisaki Y et al. (2004) Defective fetal liver erythropoiesis and T lymphopoiesis in mice lacking the phosphatidylserine receptor. Blood 103: 3362-4 PubMed GONUTS page
