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MGI:Itsn1
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Itsn1 ( synonyms: Eh domain, SH3 domain regulator of endocytosis 1, EHSH1, Ese1, Intersectin-L, Sh3p17 ) | |
| Protein Name(s) | intersectin 1 (SH3 domain protein 1A), | |
| External Links | ||
| MGI | MGI:1338069 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0005085 |
guanyl-nucleotide exchange factor activity |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0005089 |
Rho guanyl-nucleotide exchange factor activity |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0005509 |
calcium ion binding |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:2158954 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3768571 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:5294523 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005543 |
phospholipid binding |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0005622 |
intracellular |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
C |
From MGI |
|||
| GO:0005886 |
plasma membrane |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005905 |
coated pit |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0006897 |
endocytosis |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0254 |
P |
From MGI |
||
| GO:0007264 |
small GTPase mediated signal transduction |
MGI:MGI:2158954 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0016020 |
membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0472 |
C |
From MGI |
||
| GO:0019209 |
kinase activator activity |
MGI:MGI:3768571 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0019717 |
synaptosome |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0771 |
C |
From MGI |
||
| GO:0030027 |
lamellipodium |
MGI:MGI:2158954 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0030054 |
cell junction |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0965 |
C |
From MGI |
||
| GO:0030139 |
endocytic vesicle |
MGI:MGI:3768571 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0032947 |
protein complex scaffold |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0035023 |
regulation of Rho protein signal transduction |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0035556 |
intracellular signal transduction |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0042995 |
cell projection |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0966 |
C |
From MGI |
||
| GO:0043524 |
negative regulation of neuron apoptotic process |
MGI:MGI:3768571 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0045202 |
synapse |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0770 |
C |
From MGI |
||
| GO:0050790 |
regulation of catalytic activity |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0051897 |
positive regulation of protein kinase B signaling cascade |
MGI:MGI:3768571 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0070064 |
proline-rich region binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 Jenna S et al. (2002) The activity of the GTPase-activating protein CdGAP is regulated by the endocytic protein intersectin. J Biol Chem 277: 6366-73 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 2.4 Das M et al. (2007) Regulation of neuron survival through an intersectin-phosphoinositide 3'-kinase C2beta-AKT pathway. Mol Cell Biol 27: 7906-17 PubMed GONUTS page
- ↑ Primeau M et al. (2011) Cdc42 GTPase-activating protein (CdGAP) interacts with the SH3D domain of Intersectin through a novel basic-rich motif. FEBS Lett 585: 847-53 PubMed GONUTS page
