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MGI:Itpa

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Itpa ( synonyms: Itp )
Protein Name(s) inosine triphosphatase (nucleoside triphosphate pyrophosphatase),
External Links
MGI MGI:96622

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000166

nucleotide binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0547

F

From MGI

GO:0005737

cytoplasm

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:A2A2N2

C

From MGI

GO:0006193

ITP catabolic process

MGI:MGI:5009783
PMID:20081199[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:4942407

P

From MGI

GO:0009117

nucleotide metabolic process

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0546

P

From MGI

GO:0016787

hydrolase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0378

F

From MGI

GO:0016787

hydrolase activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR002637

F

From MGI

GO:0035870

dITP diphosphatase activity

MGI:MGI:5009783
PMID:20081199[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:4942407

F

From MGI

GO:0046872

metal ion binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0479

F

From MGI

GO:0047429

nucleoside-triphosphate diphosphatase activity

MGI:MGI:48978
PMID:1914521[2]

IDA: Inferred from Direct Assay

F

From MGI

GO:0047429

nucleoside-triphosphate diphosphatase activity

MGI:MGI:55148
PMID:7323947[3]

IDA: Inferred from Direct Assay

F

From MGI

GO:0051276

chromosome organization

MGI:MGI:5009783
PMID:20081199[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:4942407

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 Abolhassani N et al. (2010) NUDT16 and ITPA play a dual protective role in maintaining chromosome stability and cell growth by eliminating dIDP/IDP and dITP/ITP from nucleotide pools in mammals. Nucleic Acids Res 38: 2891-903 PubMed GONUTS page
  2. Yasue M et al. (1991) Chromosomal assignments of 23 biochemical loci of the rat by using rat x mouse somatic cell hybrids. Cytogenet Cell Genet 57: 142-8 PubMed GONUTS page
  3. Stallings RL & Siciliano MJ (1981) Confirmational, provisional, and/or regional assignment of 15 enzyme loci onto Chinese hamster autosomes 1, 2, and 7. Somatic Cell Genet 7: 683-98 PubMed GONUTS page
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