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MGI:Itga2b
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Itga2b ( synonyms: alphaIIb, CD41, GP IIb, GpIIb, platelet glycoprotein IIb ) | |
| Protein Name(s) | integrin alpha 2b, | |
| External Links | ||
| MGI | MGI:96601 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0002687 |
positive regulation of leukocyte migration |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:XP_001063315 |
P |
From MGI |
||
| GO:0004872 |
receptor activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0675 |
F |
From MGI |
||
| GO:0005925 |
focal adhesion |
MGI:MGI:3051967 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0007155 |
cell adhesion |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0130 |
P |
From MGI |
||
| GO:0007155 |
cell adhesion |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0007160 |
cell-matrix adhesion |
MGI:MGI:3051967 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0007229 |
integrin-mediated signaling pathway |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0401 |
P |
From MGI |
||
| GO:0008305 |
integrin complex |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
C |
From MGI |
|||
| GO:0009897 |
external side of plasma membrane |
MGI:MGI:2668377 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0009897 |
external side of plasma membrane |
MGI:MGI:3835249 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0009897 |
external side of plasma membrane |
MGI:MGI:4453910 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0009986 |
cell surface |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:XP_001063315 |
C |
From MGI |
||
| GO:0016020 |
membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0472 |
C |
From MGI |
||
| GO:0016021 |
integral to membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0812 |
C |
From MGI |
||
| GO:0042802 |
identical protein binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0050840 |
extracellular matrix binding |
MGI:MGI:3051967 |
IMP: Inferred from Mutant Phenotype |
F |
From MGI |
|||
| GO:0070051 |
fibrinogen binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:XP_001063315 |
F |
From MGI |
||
| GO:0070527 |
platelet aggregation |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:XP_001063315 |
P |
From MGI |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 Rout UK et al. (2004) Alpha5beta1, alphaVbeta3 and the platelet-associated integrin alphaIIbbeta3 coordinately regulate adhesion and migration of differentiating mouse trophoblast cells. Dev Biol 268: 135-51 PubMed GONUTS page
- ↑ Ferkowicz MJ et al. (2003) CD41 expression defines the onset of primitive and definitive hematopoiesis in the murine embryo. Development 130: 4393-403 PubMed GONUTS page
- ↑ Levi BP et al. (2009) Aldehyde dehydrogenase 1a1 is dispensable for stem cell function in the mouse hematopoietic and nervous systems. Blood 113: 1670-80 PubMed GONUTS page
- ↑ Serrano AG et al. (2010) Contrasting effects of Sox17- and Sox18-sustained expression at the onset of blood specification. Blood 115: 3895-8 PubMed GONUTS page
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