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MGI:Itga2

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Itga2 ( synonyms: CD49B, DX5, VLA-2 receptor, alpha 2 subunit )
Protein Name(s) integrin alpha 2,
External Links
MGI MGI:96600

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0001894

tissue homeostasis

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:XP_001075558

P

From MGI

GO:0002687

positive regulation of leukocyte migration

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:XP_001075558

P

From MGI

GO:0004872

receptor activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0675

F

From MGI

GO:0005178

integrin binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:XP_001075558

F

From MGI

GO:0005634

nucleus

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:XP_001075558

C

From MGI

GO:0005886

plasma membrane

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P17301

C

From MGI

GO:0005925

focal adhesion

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:XP_001075558

C

From MGI

GO:0006971

hypotonic response

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:XP_001075558

P

From MGI

GO:0007155

cell adhesion

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0130

P

From MGI

GO:0007155

cell adhesion

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR000413

P

From MGI

GO:0007229

integrin-mediated signaling pathway

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0401

P

From MGI

GO:0008305

integrin complex

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR000413

C

From MGI

GO:0009279

cell outer membrane

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:XP_001075558

C

From MGI

GO:0009897

external side of plasma membrane

MGI:MGI:2687118
PMID:14707119[1]

IDA: Inferred from Direct Assay

C

From MGI

GO:0009897

external side of plasma membrane

MGI:MGI:3686949
PMID:16973387[2]

IDA: Inferred from Direct Assay

C

From MGI

GO:0009986

cell surface

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:XP_001075558

C

From MGI

GO:0009986

cell surface

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P17301

C

From MGI

GO:0010634

positive regulation of epithelial cell migration

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:XP_001075558

P

From MGI

GO:0010694

positive regulation of alkaline phosphatase activity

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:XP_001075558

P

From MGI

GO:0014911

positive regulation of smooth muscle cell migration

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:XP_001075558

P

From MGI

GO:0016020

membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0472

C

From MGI

GO:0016021

integral to membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0812

C

From MGI

GO:0030424

axon

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:XP_001075558

C

From MGI

GO:0031346

positive regulation of cell projection organization

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:XP_001075558

P

From MGI

GO:0032403

protein complex binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:XP_001075558

F

From MGI

GO:0032967

positive regulation of collagen biosynthetic process

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:XP_001075558

P

From MGI

GO:0033343

positive regulation of collagen binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:XP_001075558

P

From MGI

GO:0042995

cell projection

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:XP_001075558

C

From MGI

GO:0043236

laminin binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:XP_001075558

F

From MGI

GO:0043388

positive regulation of DNA binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:XP_001075558

P

From MGI

GO:0043589

skin morphogenesis

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:XP_001075558

P

From MGI

GO:0043679

axon terminus

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:XP_001075558

C

From MGI

GO:0045178

basal part of cell

MGI:MGI:2158011
PMID:11767049[3]

IDA: Inferred from Direct Assay

C

From MGI

GO:0045184

establishment of protein localization

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:XP_001075558

P

From MGI

GO:0045727

positive regulation of translation

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:XP_001075558

P

From MGI

GO:0045785

positive regulation of cell adhesion

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:XP_001075558

P

From MGI

GO:0045987

positive regulation of smooth muscle contraction

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:XP_001075558

P

From MGI

GO:0046982

protein heterodimerization activity

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:XP_001075558

F

From MGI

GO:0048471

perinuclear region of cytoplasm

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:XP_001075558

C

From MGI

GO:0048661

positive regulation of smooth muscle cell proliferation

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:XP_001075558

P

From MGI

GO:0050729

positive regulation of inflammatory response

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:XP_001075558

P

From MGI

GO:0050927

positive regulation of positive chemotaxis

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:XP_001075558

P

From MGI

GO:0050966

detection of mechanical stimulus involved in sensory perception of pain

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:XP_001075558

P

From MGI

GO:0051971

positive regulation of transmission of nerve impulse

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:XP_001075558

P

From MGI

GO:0060100

positive regulation of phagocytosis, engulfment

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:XP_001075558

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Koike J et al. (2004) Bone marrow allograft rejection mediated by a novel murine NK receptor, NKG2I. J Exp Med 199: 137-44 PubMed GONUTS page
  2. Marie JC et al. (2006) Cellular mechanisms of fatal early-onset autoimmunity in mice with the T cell-specific targeting of transforming growth factor-beta receptor. Immunity 25: 441-54 PubMed GONUTS page
  3. Uchio-Yamada K et al. (2001) Localization of extracellular matrix receptors in ICGN mice, a strain of mice with hereditary nephrotic syndrome. J Vet Med Sci 63: 1171-8 PubMed GONUTS page
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