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MGI:Itga1

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Itga1 ( synonyms: CD49A, Vla1 )
Protein Name(s) integrin alpha 1,
External Links
MGI MGI:96599

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000187

activation of MAPK activity

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P18614

P

From MGI

GO:0001669

acrosomal vesicle

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P18614

C

From MGI

GO:0004872

receptor activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0675

F

From MGI

GO:0005178

integrin binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P18614

F

From MGI

GO:0005515

protein binding

MGI:MGI:2137765
PMID:11470831[1]

IPI: Inferred from Physical Interaction

UniProtKB:Q91ZD3
UniProtKB:Q6NV58

F

From MGI

GO:0005515

protein binding

MGI:MGI:3710037
PMID:17377534[2]

IPI: Inferred from Physical Interaction

UniProtKB:Q9QUR8

F

From MGI

GO:0005518

collagen binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P18614

F

From MGI

GO:0005624

membrane fraction

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P18614

C

From MGI

GO:0007155

cell adhesion

MGI:MGI:2658799
PMID:10528208[3]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2661083

P

From MGI

GO:0007229

integrin-mediated signaling pathway

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0401

P

From MGI

GO:0008305

integrin complex

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR000413

C

From MGI

GO:0009897

external side of plasma membrane

MGI:MGI:3686949
PMID:16973387[4]

IDA: Inferred from Direct Assay

C

From MGI

GO:0009897

external side of plasma membrane

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P18614

C

From MGI

GO:0016020

membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0472

C

From MGI

GO:0016021

integral to membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0812

C

From MGI

GO:0030593

neutrophil chemotaxis

MGI:MGI:2658799
PMID:10528208[3]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2661083

P

From MGI

GO:0042311

vasodilation

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P18614

P

From MGI

GO:0043005

neuron projection

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P18614

C

From MGI

GO:0043204

perikaryon

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P18614

C

From MGI

GO:0043525

positive regulation of neuron apoptotic process

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P18614

P

From MGI

GO:0045121

membrane raft

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P18614

C

From MGI

GO:0045123

cellular extravasation

MGI:MGI:2658799
PMID:10528208[3]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2661083

P

From MGI

GO:0045178

basal part of cell

MGI:MGI:2158011
PMID:11767049[5]

IDA: Inferred from Direct Assay

C

From MGI

GO:0046982

protein heterodimerization activity

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P18614

F

From MGI

GO:0048812

neuron projection morphogenesis

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P18614

P

From MGI

GO:0060326

cell chemotaxis

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P18614

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Brandenberger R et al. (2001) Identification and characterization of a novel extracellular matrix protein nephronectin that is associated with integrin alpha8beta1 in the embryonic kidney. J Cell Biol 154: 447-58 PubMed GONUTS page
  2. Suzuki K et al. (2007) Semaphorin 7A initiates T-cell-mediated inflammatory responses through alpha1beta1 integrin. Nature 446: 680-4 PubMed GONUTS page
  3. 3.0 3.1 3.2 Ding ZM et al. (1999) Relative contribution of LFA-1 and Mac-1 to neutrophil adhesion and migration. J Immunol 163: 5029-38 PubMed GONUTS page
  4. Marie JC et al. (2006) Cellular mechanisms of fatal early-onset autoimmunity in mice with the T cell-specific targeting of transforming growth factor-beta receptor. Immunity 25: 441-54 PubMed GONUTS page
  5. Uchio-Yamada K et al. (2001) Localization of extracellular matrix receptors in ICGN mice, a strain of mice with hereditary nephrotic syndrome. J Vet Med Sci 63: 1171-8 PubMed GONUTS page
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