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MGI:Indo
From GONUTS
Mus musculus (house mouse)
GO:0002678_!_positive_regulation_of_chronic_inflammatory_response (P) IMP with/from MGI:MGI:3505776 [2]
GO:0002830_!_positive_regulation_of_T-helper_2_type_immune_response (P) IMP with/from MGI:MGI:3505776 [2]
GO:0004833_!_tryptophan_2,3-dioxygenase_activity (F) IDA [3]
GO:0005506_!_iron_ion_binding (F) IEA with/from SP_KW:KW-0408 [4]
GO:0005737_!_cytoplasm (C) IDA [5]
GO:0006952_!_defense_response (P) TAS [6]
GO:0016491_!_oxidoreductase_activity (F) IEA with/from SP_KW:KW-0560 [4]
GO:0016702_!_oxidoreductase_activity,_acting_on_single_donors_with_incorporation_of_molecular_oxygen,_incorporation_of_two_atoms_of_oxygen (F) IEA with/from SP_KW:KW-0223 [4]
GO:0019441_!_tryptophan_catabolic_process_to_kynurenine (P) IDA [6]
GO:0019441_!_tryptophan_catabolic_process_to_kynurenine (P) IDA [3]
GO:0020037_!_heme_binding (F) IEA with/from InterPro:IPR000898 [7]
GO:0033754_!_indoleamine_2,3-dioxygenase_activity (F) IEA with/from EC:1.13.11.52 [8]
GO:0046872_!_metal_ion_binding (F) IEA with/from SP_KW:KW-0479 [4]
GO:0055114_!_oxidation_reduction (P) IEA with/from SP_KW:KW-0560 [4]
The contents of this box are automatically generated. You can help by adding information to the "Notes"
Indo:indoleamine-pyrrole 2,3 dioxygenase
Synonyms:Ido
Indo on MGI
GO terms
GO:0002666_!_positive_regulation_of_T_cell_tolerance_induction (P) IMP [1]GO:0002678_!_positive_regulation_of_chronic_inflammatory_response (P) IMP with/from MGI:MGI:3505776 [2]
GO:0002830_!_positive_regulation_of_T-helper_2_type_immune_response (P) IMP with/from MGI:MGI:3505776 [2]
GO:0004833_!_tryptophan_2,3-dioxygenase_activity (F) IDA [3]
GO:0005506_!_iron_ion_binding (F) IEA with/from SP_KW:KW-0408 [4]
GO:0005737_!_cytoplasm (C) IDA [5]
GO:0006952_!_defense_response (P) TAS [6]
GO:0016491_!_oxidoreductase_activity (F) IEA with/from SP_KW:KW-0560 [4]
GO:0016702_!_oxidoreductase_activity,_acting_on_single_donors_with_incorporation_of_molecular_oxygen,_incorporation_of_two_atoms_of_oxygen (F) IEA with/from SP_KW:KW-0223 [4]
GO:0019441_!_tryptophan_catabolic_process_to_kynurenine (P) IDA [6]
GO:0019441_!_tryptophan_catabolic_process_to_kynurenine (P) IDA [3]
GO:0020037_!_heme_binding (F) IEA with/from InterPro:IPR000898 [7]
GO:0033754_!_indoleamine_2,3-dioxygenase_activity (F) IEA with/from EC:1.13.11.52 [8]
GO:0046872_!_metal_ion_binding (F) IEA with/from SP_KW:KW-0479 [4]
GO:0055114_!_oxidation_reduction (P) IEA with/from SP_KW:KW-0560 [4]
The contents of this box are automatically generated. You can help by adding information to the "Notes"
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Munn DH et al. (1998) Prevention of allogeneic fetal rejection by tryptophan catabolism. Science 281: 1191-3 PubMed GONUTS page
- ↑ 2.0 2.1 Xu H et al. (2008) Indoleamine 2,3-dioxygenase in lung dendritic cells promotes Th2 responses and allergic inflammation. Proc Natl Acad Sci U S A 105: 6690-5 PubMed GONUTS page
- ↑ 3.0 3.1 Fallarino F et al. (2002) Functional expression of indoleamine 2,3-dioxygenase by murine CD8 alpha(+) dendritic cells. Int Immunol 14: 65-8 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 4.3 4.4 MGI annotation MGI:1354194
- ↑ Metz R et al. (2007) Novel tryptophan catabolic enzyme IDO2 is the preferred biochemical target of the antitumor indoleamine 2,3-dioxygenase inhibitory compound D-1-methyl-tryptophan. Cancer Res 67: 7082-7 PubMed GONUTS page
- ↑ 6.0 6.1 Takikawa O et al. (1986) Tryptophan degradation in mice initiated by indoleamine 2,3-dioxygenase. J Biol Chem 261: 3648-53 PubMed GONUTS page
- ↑ MGI annotation MGI:2152098
- ↑ MGI annotation MGI:2152096
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