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MGI:Il8rb

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Il8rb ( synonyms: CD128, Cmkar2, CXCR2, Gpcr16, IL-8rb, IL-8Rh, IL8RA )
Protein Name(s) interleukin 8 receptor, beta,
External Links
MGI MGI:105303

Annotations

Qualifier GO ID GO term name Reference(s) Evidence Code with/from Aspect Notes Status
GO:0004871

signal transducer activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

SP_KW:KW-0807

F

From MGI

GO:0004872

receptor activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

SP_KW:KW-0675

F

From MGI

GO:0004918

interleukin-8 receptor activity

MGI:MGI:79768
PMID:8631787[1]

TAS: Traceable Author Statement

F

From MGI

GO:0004930

G-protein coupled receptor activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

SP_KW:KW-0297

F

From MGI

GO:0004950

chemokine receptor activity

MGI:MGI:2447219
PMID:12470609[2]

TAS: Traceable Author Statement

F

From MGI

GO:0004950

chemokine receptor activity

MGI:MGI:3623669
PMID:16618742[3]

IDA: Inferred from Direct Assay

F

From MGI

GO:0005515

protein binding

MGI:MGI:3028809
PMID:14764687[4]

IPI: Inferred from Physical Interaction

UniProtKB:Q6W5C0

F

From MGI

GO:0005886

plasma membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

SP_KW:KW-1003

C

From MGI

GO:0006915

apoptosis

MGI:MGI:3623669
PMID:16618742[3]

IDA: Inferred from Direct Assay

P

From MGI

GO:0006935

chemotaxis

MGI:MGI:2447219
PMID:12470609[2]

TAS: Traceable Author Statement

P

From MGI

GO:0007165

signal transduction

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

SP_KW:KW-0807

P

From MGI

GO:0007186

G-protein coupled receptor protein signaling pathway

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

SP_KW:KW-0297

P

From MGI

GO:0007186

G-protein coupled receptor protein signaling pathway

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR000276

P

From MGI

GO:0016020

membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

SP_KW:KW-0472

C

From MGI

GO:0016021

integral to membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

SP_KW:KW-0812

C

From MGI

GO:0016021

integral to membrane

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR000276,InterPro:IPR000174,InterPro:IPR000057

C

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Boring L et al. (1996) Molecular cloning and functional expression of murine JE (monocyte chemoattractant protein 1) and murine macrophage inflammatory protein 1alpha receptors: evidence for two closely linked C-C chemokine receptors on chromosome 9. J Biol Chem 271: 7551-8 PubMed GONUTS page
  2. 2.0 2.1 Lavigne MC et al. (2002) The N-formylpeptide receptor (FPR) and a second G(i)-coupled receptor mediate fMet-Leu-Phe-stimulated activation of NADPH oxidase in murine neutrophils. Cell Immunol 218: 7-12 PubMed GONUTS page
  3. 3.0 3.1 Wislez M et al. (2006) High expression of ligands for chemokine receptor CXCR2 in alveolar epithelial neoplasia induced by oncogenic kras. Cancer Res 66: 4198-207 PubMed GONUTS page
  4. Nolan KF et al. (2004) IL-10-conditioned dendritic cells, decommissioned for recruitment of adaptive immunity, elicit innate inflammatory gene products in response to danger signals. J Immunol 172: 2201-9 PubMed GONUTS page
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