Ambox notice.png

GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.

You can help reduce stress on the server by:

  1. not reloading pages frequently - this just adds
  2. opening links in new windows (so you can read the old page)

MGI:Il21

From GONUTS
Jump to: navigation, search

Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Il21
Protein Name(s) interleukin 21,
External Links
MGI MGI:1890474

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0001783

B cell apoptotic process

MGI:MGI:3505636
PMID:15494482[1]

NAS: Non-traceable Author Statement

P

From MGI

GO:0002729

positive regulation of natural killer cell cytokine production

MGI:MGI:3028812
PMID:14764669[2]

IDA: Inferred from Direct Assay

P

From MGI

GO:0005125

cytokine activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0202

F

From MGI

GO:0005126

cytokine receptor binding

MGI:MGI:1926991
PMID:11081504[3]

IDA: Inferred from Direct Assay

F

From MGI

GO:0005134

interleukin-2 receptor binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q9HBE4

F

From MGI

GO:0005576

extracellular region

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0964

C

From MGI

GO:0005576

extracellular region

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR003443

C

From MGI

GO:0005615

extracellular space

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0202

C

From MGI

GO:0006955

immune response

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR003443

P

From MGI

GO:0032733

positive regulation of interleukin-10 production

MGI:MGI:3028812
PMID:14764669[2]

IDA: Inferred from Direct Assay

P

From MGI

GO:0032740

positive regulation of interleukin-17 production

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q9HBE4

P

From MGI

GO:0032825

positive regulation of natural killer cell differentiation

MGI:MGI:3028812
PMID:14764669[2]

IDA: Inferred from Direct Assay

P

From MGI

GO:0042102

positive regulation of T cell proliferation

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q9HBE4

P

From MGI

GO:0045078

positive regulation of interferon-gamma biosynthetic process

MGI:MGI:3028812
PMID:14764669[2]

IDA: Inferred from Direct Assay

P

From MGI

GO:0045579

positive regulation of B cell differentiation

MGI:MGI:3505636
PMID:15494482[1]

NAS: Non-traceable Author Statement

P

From MGI

GO:0045954

positive regulation of natural killer cell mediated cytotoxicity

MGI:MGI:3028812
PMID:14764669[2]

IDA: Inferred from Direct Assay

P

From MGI

GO:0048469

cell maturation

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q9HBE4

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 Ozaki K et al. (2004) Regulation of B cell differentiation and plasma cell generation by IL-21, a novel inducer of Blimp-1 and Bcl-6. J Immunol 173: 5361-71 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 Brady J et al. (2004) IL-21 induces the functional maturation of murine NK cells. J Immunol 172: 2048-58 PubMed GONUTS page
  3. Parrish-Novak J et al. (2000) Interleukin 21 and its receptor are involved in NK cell expansion and regulation of lymphocyte function. Nature 408: 57-63 PubMed GONUTS page
Personal tools
Namespaces
Variants
Actions
Navigation
Cacao
Journal Clubs
page contributors
Toolbox