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MGI:Il1rn

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Il1rn ( synonyms: IL-1ra )
Protein Name(s) interleukin 1 receptor antagonist,
External Links
MGI MGI:96547

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0001960

negative regulation of cytokine-mediated signaling pathway

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P18510

P

From MGI

GO:0004872

receptor activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0675

F

From MGI

GO:0005149

interleukin-1 receptor binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P18510

F

From MGI

GO:0005150

interleukin-1, Type I receptor binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P18510

F

From MGI

GO:0005151

interleukin-1, Type II receptor binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P18510

F

From MGI

GO:0005152

interleukin-1 receptor antagonist activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P18510

F

From MGI

GO:0005576

extracellular region

MGI:MGI:3051178
PMID:15240711[1]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005615

extracellular space

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P18510

C

From MGI

GO:0005623

cell

MGI:MGI:2675567
PMID:12975454[2]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2157397

C

From MGI

GO:0005634

nucleus

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P18510

C

From MGI

GO:0005737

cytoplasm

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P18510

C

From MGI

GO:0005813

centrosome

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P18510

C

From MGI

GO:0006629

lipid metabolic process

MGI:MGI:2675567
PMID:12975454[2]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2157397

P

From MGI

GO:0006953

acute-phase response

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P18510

P

From MGI

GO:0007613

memory

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P25086

P

From MGI

GO:0014050

negative regulation of glutamate secretion

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P25086

P

From MGI

GO:0030073

insulin secretion

MGI:MGI:2675567
PMID:12975454[2]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2157397

P

From MGI

GO:0031982

vesicle

MGI:MGI:3051178
PMID:15240711[1]

IDA: Inferred from Direct Assay

C

From MGI

GO:0034115

negative regulation of heterotypic cell-cell adhesion

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P18510

P

From MGI

GO:0043066

negative regulation of apoptotic process

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P25086

P

From MGI

GO:0043507

positive regulation of JUN kinase activity

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P25086

P

From MGI

GO:0045352

interleukin-1 Type I receptor antagonist activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P18510

F

From MGI

GO:0045353

interleukin-1 Type II receptor antagonist activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P18510

F

From MGI

GO:0051384

response to glucocorticoid stimulus

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P18510

P

From MGI

GO:1900116

extracellular negative regulation of signal transduction

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P18510

P

From MGI

GO:2000660

negative regulation of interleukin-1-mediated signaling pathway

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P18510

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 Wilson HL et al. (2004) Secretion of intracellular IL-1 receptor antagonist (type 1) is dependent on P2X7 receptor activation. J Immunol 173: 1202-8 PubMed GONUTS page
  2. 2.0 2.1 2.2 Matsuki T et al. (2003) IL-1 plays an important role in lipid metabolism by regulating insulin levels under physiological conditions. J Exp Med 198: 877-88 PubMed GONUTS page
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