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MGI:Il1r1

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Il1r1 ( synonyms: CD121a, IL-1 receptor alpha chain, IL-iR, Il1r-1 )
Protein Name(s) interleukin 1 receptor, type I,
External Links
MGI MGI:96545

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0002020

protease binding

MGI:MGI:4942254
PMID:12135759[1]

IPI: Inferred from Physical Interaction

UniProtKB:Q05910

F

From MGI

GO:0004871

signal transducer activity

MGI:MGI:2179626
PMID:11880380[2]

IDA: Inferred from Direct Assay

F

From MGI

GO:0004872

receptor activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0675

F

From MGI

GO:0004888

transmembrane signaling receptor activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR004075

F

From MGI

GO:0004908

interleukin-1 receptor activity

MGI:MGI:2179626
PMID:11880380[2]

IDA: Inferred from Direct Assay

F

From MGI

GO:0004908

interleukin-1 receptor activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P14778

F

From MGI

GO:0004909

interleukin-1, Type I, activating receptor activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR004076

F

From MGI

GO:0005161

platelet-derived growth factor receptor binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P14778

F

From MGI

GO:0005515

protein binding

MGI:MGI:3056874
PMID:15292196[3]

IPI: Inferred from Physical Interaction

UniProtKB:Q8R4K2
UniProtKB:Q62406

F

From MGI

GO:0005515

protein binding

MGI:MGI:5142401
PMID:1828071[4]

IPI: Inferred from Physical Interaction

UniProtKB:P18510

F

From MGI

GO:0005576

extracellular region

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0964

C

From MGI

GO:0005622

intracellular

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR000157

C

From MGI

GO:0005886

plasma membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-1003

C

From MGI

GO:0007165

signal transduction

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR004075
InterPro:IPR000157

P

From MGI

GO:0009986

cell surface

MGI:MGI:4410397
PMID:19833765[5]

IDA: Inferred from Direct Assay

C

From MGI

GO:0014069

postsynaptic density

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:Q02955

C

From MGI

GO:0016020

membrane

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P14778

C

From MGI

GO:0016021

integral to membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0812

C

From MGI

GO:0019221

cytokine-mediated signaling pathway

MGI:MGI:2179626
PMID:11880380[2]

IDA: Inferred from Direct Assay

P

From MGI

GO:0019221

cytokine-mediated signaling pathway

MGI:MGI:3056874
PMID:15292196[3]

IDA: Inferred from Direct Assay

P

From MGI

GO:0031224

intrinsic to membrane

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR004075

C

From MGI

GO:0035255

ionotropic glutamate receptor binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:Q02955

F

From MGI

GO:0043234

protein complex

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:Q02955

C

From MGI

GO:0045087

innate immune response

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR004075

P

From MGI

GO:0070498

interleukin-1-mediated signaling pathway

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR004076

P

From MGI

GO:0070498

interleukin-1-mediated signaling pathway

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:Q02955

P

From MGI

GO:0070498

interleukin-1-mediated signaling pathway

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P14778

P

From MGI

GO:0070555

response to interleukin-1

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P14778

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Amour A et al. (2002) The enzymatic activity of ADAM8 and ADAM9 is not regulated by TIMPs. FEBS Lett 524: 154-8 PubMed GONUTS page
  2. 2.0 2.1 2.2 Radons J et al. (2002) Identification of essential regions in the cytoplasmic tail of interleukin-1 receptor accessory protein critical for interleukin-1 signaling. J Biol Chem 277: 16456-63 PubMed GONUTS page
  3. 3.0 3.1 Lye E et al. (2004) The role of interleukin 1 receptor-associated kinase-4 (IRAK-4) kinase activity in IRAK-4-mediated signaling. J Biol Chem 279: 40653-8 PubMed GONUTS page
  4. Dripps DJ et al. (1991) Interleukin-1 (IL-1) receptor antagonist binds to the 80-kDa IL-1 receptor but does not initiate IL-1 signal transduction. J Biol Chem 266: 10331-6 PubMed GONUTS page
  5. Inlay MA et al. (2009) Ly6d marks the earliest stage of B-cell specification and identifies the branchpoint between B-cell and T-cell development. Genes Dev 23: 2376-81 PubMed GONUTS page
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