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MGI:Il17f

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Il17f
Protein Name(s) interleukin 17F,
External Links
MGI MGI:2676631

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0005125

cytokine activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q96PD4

F

From MGI

GO:0005126

cytokine receptor binding

MGI:MGI:4360610
PMID:17911633[1]

IPI: Inferred from Physical Interaction

UniProtKB:Q8K4C2

F

From MGI

GO:0005576

extracellular region

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0964

C

From MGI

GO:0005576

extracellular region

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR020440
InterPro:IPR010345

C

From MGI

GO:0005615

extracellular space

MGI:MGI:4366407
PMID:17982105[2]

IDA: Inferred from Direct Assay

C

From MGI

GO:0006029

proteoglycan metabolic process

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q96PD4

P

From MGI

GO:0006954

inflammatory response

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR020440
InterPro:IPR010345

P

From MGI

GO:0016525

negative regulation of angiogenesis

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q96PD4

P

From MGI

GO:0017015

regulation of transforming growth factor beta receptor signaling pathway

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q96PD4

P

From MGI

GO:0019955

cytokine binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q96PD4

F

From MGI

GO:0042089

cytokine biosynthetic process

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q96PD4

P

From MGI

GO:0042109

lymphotoxin A biosynthetic process

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q96PD4

P

From MGI

GO:0042803

protein homodimerization activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q96PD4

F

From MGI

GO:0045076

regulation of interleukin-2 biosynthetic process

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q96PD4

P

From MGI

GO:0045408

regulation of interleukin-6 biosynthetic process

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q96PD4

P

From MGI

GO:0045414

regulation of interleukin-8 biosynthetic process

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q96PD4

P

From MGI

GO:0045423

regulation of granulocyte macrophage colony-stimulating factor biosynthetic process

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q96PD4

P

From MGI

GO:0045944

positive regulation of transcription from RNA polymerase II promoter

MGI:MGI:3722056
PMID:16982811[3]

IDA: Inferred from Direct Assay

P

From MGI

GO:0045944

positive regulation of transcription from RNA polymerase II promoter

MGI:MGI:3722056
PMID:16982811[3]

IGI: Inferred from Genetic Interaction

MGI:MGI:1355307

P

From MGI

GO:0051216

cartilage development

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q96PD4

P

From MGI

GO:1900017

positive regulation of cytokine production involved in inflammatory response

MGI:MGI:3785663
PMID:16785495[4]

IDA: Inferred from Direct Assay

P

From MGI

GO:1900017

positive regulation of cytokine production involved in inflammatory response

MGI:MGI:3785663
PMID:16785495[4]

IGI: Inferred from Genetic Interaction

MGI:MGI:107399

P

From MGI

GO:1900017

positive regulation of cytokine production involved in inflammatory response

MGI:MGI:4366407
PMID:17982105[2]

IDA: Inferred from Direct Assay

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Kuestner RE et al. (2007) Identification of the IL-17 receptor related molecule IL-17RC as the receptor for IL-17F. J Immunol 179: 5462-73 PubMed GONUTS page
  2. 2.0 2.1 Yamaguchi Y et al. (2007) IL-17B and IL-17C are associated with TNF-alpha production and contribute to the exacerbation of inflammatory arthritis. J Immunol 179: 7128-36 PubMed GONUTS page
  3. 3.0 3.1 Liang SC et al. (2006) Interleukin (IL)-22 and IL-17 are coexpressed by Th17 cells and cooperatively enhance expression of antimicrobial peptides. J Exp Med 203: 2271-9 PubMed GONUTS page
  4. 4.0 4.1 Toy D et al. (2006) Cutting edge: interleukin 17 signals through a heteromeric receptor complex. J Immunol 177: 36-9 PubMed GONUTS page
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