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MGI:Il12rb2

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Il12rb2 ( synonyms: Ifnm, IL-12RB2 )
Protein Name(s) interleukin 12 receptor, beta 2,
External Links
MGI MGI:1270861

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0004872

receptor activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0675

F

From MGI

GO:0004896

cytokine receptor activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR003529

F

From MGI

GO:0009897

external side of plasma membrane

MGI:MGI:3050756
PMID:15220916[1]

IDA: Inferred from Direct Assay

C

From MGI

GO:0016020

membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0472

C

From MGI

GO:0016020

membrane

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR003529

C

From MGI

GO:0016021

integral to membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0812

C

From MGI

GO:0018108

peptidyl-tyrosine phosphorylation

MGI:MGI:2148358
PMID:11489994[2]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2156401

P

From MGI

GO:0019221

cytokine-mediated signaling pathway

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR003529

P

From MGI

GO:0019901

protein kinase binding

MGI:MGI:2148358
PMID:11489994[2]

IPI: Inferred from Physical Interaction

UniProtKB:Q62120

F

From MGI

GO:0032496

response to lipopolysaccharide

MGI:MGI:2148358
PMID:11489994[2]

IGI: Inferred from Genetic Interaction

MGI:MGI:96824

P

From MGI

GO:0032609

interferon-gamma production

MGI:MGI:2148358
PMID:11489994[2]

IGI: Inferred from Genetic Interaction

MGI:MGI:96824

P

From MGI

GO:0032729

positive regulation of interferon-gamma production

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q99665

P

From MGI

GO:0034097

response to cytokine stimulus

MGI:MGI:2148358
PMID:11489994[2]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2156401

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Watanabe T et al. (2004) NOD2 is a negative regulator of Toll-like receptor 2-mediated T helper type 1 responses. Nat Immunol 5: 800-8 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 Poltorak A et al. (2001) A point mutation in the IL-12R beta 2 gene underlies the IL-12 unresponsiveness of Lps-defective C57BL/10ScCr mice. J Immunol 167: 2106-11 PubMed GONUTS page
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