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MGI:Il11ra1

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Il11ra1 ( synonyms: Il-11ra, Il-11ra-alpha, Il11ra, NR1 )
Protein Name(s) interleukin 11 receptor, alpha chain 1,
External Links
MGI MGI:107426

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0001779

natural killer cell differentiation

MGI:MGI:3505799
PMID:15499555[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2177774

P

From MGI

GO:0001890

placenta development

MGI:MGI:1276212
PMID:9679067[2]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2177774

P

From MGI

GO:0004872

receptor activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0675

F

From MGI

GO:0004896

cytokine receptor activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR003530

F

From MGI

GO:0004921

interleukin-11 receptor activity

MGI:MGI:69257
PMID:7957045[3]

IDA: Inferred from Direct Assay

F

From MGI

GO:0008284

positive regulation of cell proliferation

MGI:MGI:69257
PMID:7957045[3]

IDA: Inferred from Direct Assay

P

From MGI

GO:0016020

membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0472

C

From MGI

GO:0016020

membrane

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR003530

C

From MGI

GO:0016021

integral to membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0812

C

From MGI

GO:0019221

cytokine-mediated signaling pathway

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR003530

P

From MGI

GO:0019221

cytokine-mediated signaling pathway

MGI:MGI:69257
PMID:7957045[3]

IDA: Inferred from Direct Assay

P

From MGI

GO:0019970

interleukin-11 binding

MGI:MGI:69257
PMID:7957045[3]

IPI: Inferred from Physical Interaction

UniProtKB:P47873

F

From MGI

GO:0032502

developmental process

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q14626

P

From MGI

GO:0046697

decidualization

MGI:MGI:1197428
PMID:9500603[4]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2177778

P

From MGI

GO:0046697

decidualization

MGI:MGI:1276212
PMID:9679067[2]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2177774

P

From MGI

GO:0060135

maternal process involved in female pregnancy

MGI:MGI:1197428
PMID:9500603[4]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2177778

P

From MGI

GO:0060135

maternal process involved in female pregnancy

MGI:MGI:1276212
PMID:9679067[2]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2177774

P

From MGI

GO:0060322

head development

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q14626

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Ain R et al. (2004) Interleukin-11 signaling is required for the differentiation of natural killer cells at the maternal-fetal interface. Dev Dyn 231: 700-8 PubMed GONUTS page
  2. 2.0 2.1 2.2 Bilinski P et al. (1998) Maternal IL-11Ralpha function is required for normal decidua and fetoplacental development in mice. Genes Dev 12: 2234-43 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 Hilton DJ et al. (1994) Cloning of a murine IL-11 receptor alpha-chain; requirement for gp130 for high affinity binding and signal transduction. EMBO J 13: 4765-75 PubMed GONUTS page
  4. 4.0 4.1 Robb L et al. (1998) Infertility in female mice lacking the receptor for interleukin 11 is due to a defective uterine response to implantation. Nat Med 4: 303-8 PubMed GONUTS page
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