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MGI:Ighg1
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Ighg1 ( synonyms: IgG1, Igh-4 ) | |
| Protein Name(s) | immunoglobulin heavy constant gamma 1 (G1m marker), | |
| External Links | ||
| MGI | MGI:96446 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0001788 |
antibody-dependent cellular cytotoxicity |
MGI:MGI:2683749 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0001798 |
positive regulation of type IIa hypersensitivity |
MGI:MGI:2177393 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0001798 |
positive regulation of type IIa hypersensitivity |
MGI:MGI:2683747 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0001812 |
positive regulation of type I hypersensitivity |
MGI:MGI:2683749 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0001812 |
positive regulation of type I hypersensitivity |
MGI:MGI:2683928 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0001812 |
positive regulation of type I hypersensitivity |
MGI:MGI:78617 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0002455 |
humoral immune response mediated by circulating immunoglobulin |
MGI:MGI:1926579 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0002455 |
humoral immune response mediated by circulating immunoglobulin |
MGI:MGI:3037416 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0002455 |
humoral immune response mediated by circulating immunoglobulin |
MGI:MGI:3528786 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0002455 |
humoral immune response mediated by circulating immunoglobulin |
MGI:MGI:3620376 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0002455 |
humoral immune response mediated by circulating immunoglobulin |
MGI:MGI:3690573 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0002455 |
humoral immune response mediated by circulating immunoglobulin |
MGI:MGI:67606 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0002455 |
humoral immune response mediated by circulating immunoglobulin |
MGI:MGI:77753 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0003823 |
antigen binding |
MGI:MGI:1354084 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0003823 |
antigen binding |
MGI:MGI:1889050 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0003823 |
antigen binding |
MGI:MGI:1926579 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0003823 |
antigen binding |
MGI:MGI:2153656 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0003823 |
antigen binding |
MGI:MGI:2177393 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0003823 |
antigen binding |
MGI:MGI:2664488 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0003823 |
antigen binding |
MGI:MGI:2670820 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0003823 |
antigen binding |
MGI:MGI:2679188 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0003823 |
antigen binding |
MGI:MGI:2679189 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0003823 |
antigen binding |
MGI:MGI:2683747 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0003823 |
antigen binding |
MGI:MGI:2683749 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0003823 |
antigen binding |
MGI:MGI:2683928 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0003823 |
antigen binding |
MGI:MGI:2684211 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0003823 |
antigen binding |
MGI:MGI:3037416 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0003823 |
antigen binding |
MGI:MGI:3528786 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0003823 |
antigen binding |
MGI:MGI:3620376 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0003823 |
antigen binding |
MGI:MGI:3690573 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0003823 |
antigen binding |
MGI:MGI:67606 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0003823 |
antigen binding |
MGI:MGI:67723 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0003823 |
antigen binding |
MGI:MGI:77753 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0003823 |
antigen binding |
MGI:MGI:78617 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0003823 |
antigen binding |
MGI:MGI:82508 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0005615 |
extracellular space |
MGI:MGI:3718932 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0006910 |
phagocytosis, recognition |
MGI:MGI:2664488 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0006910 |
phagocytosis, recognition |
MGI:MGI:2679188 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0006910 |
phagocytosis, recognition |
MGI:MGI:2679189 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0006910 |
phagocytosis, recognition |
MGI:MGI:2683747 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0006910 |
phagocytosis, recognition |
MGI:MGI:2683749 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0006910 |
phagocytosis, recognition |
MGI:MGI:82508 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0006911 |
phagocytosis, engulfment |
MGI:MGI:2177393 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0006911 |
phagocytosis, engulfment |
MGI:MGI:2664488 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0006911 |
phagocytosis, engulfment |
MGI:MGI:2679188 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0006911 |
phagocytosis, engulfment |
MGI:MGI:2679189 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0006911 |
phagocytosis, engulfment |
MGI:MGI:2683747 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0006911 |
phagocytosis, engulfment |
MGI:MGI:2683749 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0006911 |
phagocytosis, engulfment |
MGI:MGI:82508 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0006958 |
complement activation, classical pathway |
MGI:MGI:2683928 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0009897 |
external side of plasma membrane |
MGI:MGI:3817382 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0016064 |
immunoglobulin mediated immune response |
MGI:MGI:1340171 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0016064 |
immunoglobulin mediated immune response |
MGI:MGI:1354084 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0016064 |
immunoglobulin mediated immune response |
MGI:MGI:1889050 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0016064 |
immunoglobulin mediated immune response |
MGI:MGI:2153656 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0016064 |
immunoglobulin mediated immune response |
MGI:MGI:2670820 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0016064 |
immunoglobulin mediated immune response |
MGI:MGI:2679189 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0016064 |
immunoglobulin mediated immune response |
MGI:MGI:2684211 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0016064 |
immunoglobulin mediated immune response |
MGI:MGI:67723 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0016064 |
immunoglobulin mediated immune response |
MGI:MGI:78617 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0019731 |
antibacterial humoral response |
MGI:MGI:2664488 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0019731 |
antibacterial humoral response |
MGI:MGI:3690573 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0042571 |
immunoglobulin complex, circulating |
MGI:MGI:1354084 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0042571 |
immunoglobulin complex, circulating |
MGI:MGI:1889050 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0042571 |
immunoglobulin complex, circulating |
MGI:MGI:1926579 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0042571 |
immunoglobulin complex, circulating |
MGI:MGI:2153656 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0042571 |
immunoglobulin complex, circulating |
MGI:MGI:2664488 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0042571 |
immunoglobulin complex, circulating |
MGI:MGI:2670820 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0042571 |
immunoglobulin complex, circulating |
MGI:MGI:2671681 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0042571 |
immunoglobulin complex, circulating |
MGI:MGI:2679189 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0042571 |
immunoglobulin complex, circulating |
MGI:MGI:2683928 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0042571 |
immunoglobulin complex, circulating |
MGI:MGI:2684211 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0042571 |
immunoglobulin complex, circulating |
MGI:MGI:3037416 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0042571 |
immunoglobulin complex, circulating |
MGI:MGI:3039643 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0042571 |
immunoglobulin complex, circulating |
MGI:MGI:3528786 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0042571 |
immunoglobulin complex, circulating |
MGI:MGI:3620376 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0042571 |
immunoglobulin complex, circulating |
MGI:MGI:3690573 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0042571 |
immunoglobulin complex, circulating |
MGI:MGI:3695768 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0042571 |
immunoglobulin complex, circulating |
MGI:MGI:62368 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0042571 |
immunoglobulin complex, circulating |
MGI:MGI:67606 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0042571 |
immunoglobulin complex, circulating |
MGI:MGI:67723 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0042571 |
immunoglobulin complex, circulating |
MGI:MGI:77753 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0042571 |
immunoglobulin complex, circulating |
MGI:MGI:78617 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0042742 |
defense response to bacterium |
MGI:MGI:2664488 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0050766 |
positive regulation of phagocytosis |
MGI:MGI:2177393 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0050766 |
positive regulation of phagocytosis |
MGI:MGI:2664488 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0050766 |
positive regulation of phagocytosis |
MGI:MGI:2679188 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0050766 |
positive regulation of phagocytosis |
MGI:MGI:2679189 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0050766 |
positive regulation of phagocytosis |
MGI:MGI:2683747 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0050766 |
positive regulation of phagocytosis |
MGI:MGI:2683749 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0050766 |
positive regulation of phagocytosis |
MGI:MGI:82508 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0050778 |
positive regulation of immune response |
MGI:MGI:1340171 |
IDA: Inferred from Direct Assay |
P |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 Hazenbos WL et al. (1998) Murine IgG1 complexes trigger immune effector functions predominantly via Fc gamma RIII (CD16). J Immunol 161: 3026-32 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 Azeredo da Silveira S et al. (2002) Complement activation selectively potentiates the pathogenicity of the IgG2b and IgG3 isotypes of a high affinity anti-erythrocyte autoantibody. J Exp Med 195: 665-72 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 3.4 Meyer D et al. (1998) FcgammaRIII (CD16)-deficient mice show IgG isotype-dependent protection to experimental autoimmune hemolytic anemia. Blood 92: 3997-4002 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 4.3 Hirayama N et al. (1982) Biological activities of antitrinitrophenyl and antidinitrophenyl mouse monoclonal antibodies. Proc Natl Acad Sci U S A 79: 613-5 PubMed GONUTS page
- ↑ 5.0 5.1 5.2 5.3 Takai T et al. (1996) Augmented humoral and anaphylactic responses in Fc gamma RII-deficient mice. Nature 379: 346-9 PubMed GONUTS page
- ↑ 6.0 6.1 6.2 Chen Q et al. (2000) Development of Th1-type immune responses requires the type I cytokine receptor TCCR. Nature 407: 916-20 PubMed GONUTS page
- ↑ 7.0 7.1 7.2 Castigli E et al. (2004) Impaired IgA class switching in APRIL-deficient mice. Proc Natl Acad Sci U S A 101: 3903-8 PubMed GONUTS page
- ↑ 8.0 8.1 8.2 Kobayashi KS et al. (2005) Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract. Science 307: 731-4 PubMed GONUTS page
- ↑ 9.0 9.1 9.2 Nishimura H & Strominger JL (2006) Involvement of a tissue-specific autoantibody in skin disorders of murine systemic lupus erythematosus and autoinflammatory diseases. Proc Natl Acad Sci U S A 103: 3292-7 PubMed GONUTS page
- ↑ 10.0 10.1 10.2 10.3 Hultgren O et al. (1998) TNF/lymphotoxin-alpha double-mutant mice resist septic arthritis but display increased mortality in response to Staphylococcus aureus. J Immunol 161: 5937-42 PubMed GONUTS page
- ↑ 11.0 11.1 11.2 Fujiwara H et al. (1994) The absence of IgE antibody-mediated augmentation of immune responses in CD23-deficient mice. Proc Natl Acad Sci U S A 91: 6835-9 PubMed GONUTS page
- ↑ 12.0 12.1 12.2 Kong YY et al. (1995) Differential requirements of CD45 for lymphocyte development and function. Eur J Immunol 25: 3431-6 PubMed GONUTS page
- ↑ 13.0 13.1 13.2 Helgason CD et al. (2000) A dual role for Src homology 2 domain-containing inositol-5-phosphatase (SHIP) in immunity: aberrant development and enhanced function of b lymphocytes in ship -/- mice. J Exp Med 191: 781-94 PubMed GONUTS page
- ↑ 14.0 14.1 14.2 Roes J & Rajewsky K (1993) Immunoglobulin D (IgD)-deficient mice reveal an auxiliary receptor function for IgD in antigen-mediated recruitment of B cells. J Exp Med 177: 45-55 PubMed GONUTS page
- ↑ 15.0 15.1 15.2 Alfonso C et al. (2001) The impact of H2-DM on humoral immune responses. J Immunol 167: 6348-55 PubMed GONUTS page
- ↑ 16.0 16.1 16.2 16.3 16.4 16.5 16.6 Ioan-Facsinay A et al. (2002) FcgammaRI (CD64) contributes substantially to severity of arthritis, hypersensitivity responses, and protection from bacterial infection. Immunity 16: 391-402 PubMed GONUTS page
- ↑ 17.0 17.1 17.2 Gerth AJ et al. (2003) T-bet regulates T-independent IgG2a class switching. Int Immunol 15: 937-44 PubMed GONUTS page
- ↑ 18.0 18.1 18.2 18.3 Gavin AL et al. (1998) Identification of the mouse IgG3 receptor: implications for antibody effector function at the interface between innate and adaptive immunity. J Immunol 160: 20-3 PubMed GONUTS page
- ↑ 19.0 19.1 19.2 19.3 19.4 19.5 Barnes N et al. (2002) FcgammaRI-deficient mice show multiple alterations to inflammatory and immune responses. Immunity 16: 379-89 PubMed GONUTS page
- ↑ 20.0 20.1 20.2 Ovary Z et al. (1970) Passive anaphylaxis in mice with gamma-G antibodies. V. Competitive effects of different immunoglobulins and inhibition of reactions with antiglobulin sera. Immunology 19: 715-27 PubMed GONUTS page
- ↑ 21.0 21.1 21.2 Oettgen HC et al. (1994) Active anaphylaxis in IgE-deficient mice. Nature 370: 367-70 PubMed GONUTS page
- ↑ 22.0 22.1 22.2 22.3 Hazenbos WL et al. (1996) Impaired IgG-dependent anaphylaxis and Arthus reaction in Fc gamma RIII (CD16) deficient mice. Immunity 5: 181-8 PubMed GONUTS page
- ↑ Amsen D et al. (2007) Direct regulation of Gata3 expression determines the T helper differentiation potential of Notch. Immunity 27: 89-99 PubMed GONUTS page
- ↑ de Yébenes VG et al. (2008) miR-181b negatively regulates activation-induced cytidine deaminase in B cells. J Exp Med 205: 2199-206 PubMed GONUTS page
- ↑ 25.0 25.1 Wernersson S et al. (1999) IgG-mediated enhancement of antibody responses is low in Fc receptor gamma chain-deficient mice and increased in Fc gamma RII-deficient mice. J Immunol 163: 618-22 PubMed GONUTS page
- ↑ Liljedahl M et al. (1998) Altered antigen presentation in mice lacking H2-O. Immunity 8: 233-43 PubMed GONUTS page
- ↑ Egawa T et al. (2003) Requirement for CARMA1 in antigen receptor-induced NF-kappa B activation and lymphocyte proliferation. Curr Biol 13: 1252-8 PubMed GONUTS page
- ↑ Lin W et al. (2005) Allergic dysregulation and hyperimmunoglobulinemia E in Foxp3 mutant mice. J Allergy Clin Immunol 116: 1106-15 PubMed GONUTS page
- ↑ Shahinian A et al. (1993) Differential T cell costimulatory requirements in CD28-deficient mice. Science 261: 609-12 PubMed GONUTS page
