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MGI:Ighd

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Ighd ( synonyms: IgD )
Protein Name(s) immunoglobulin heavy constant delta,
External Links
MGI MGI:96447

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0003823

antigen binding

MGI:MGI:1889050
PMID:8418208[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:1857186

F

From MGI

GO:0009897

external side of plasma membrane

MGI:MGI:1095647
PMID:9254656[2]

IDA: Inferred from Direct Assay

C

From MGI

GO:0009897

external side of plasma membrane

MGI:MGI:1332382
PMID:10072077[3]

IDA: Inferred from Direct Assay

C

From MGI

GO:0009897

external side of plasma membrane

MGI:MGI:1354084
PMID:10704460[4]

IDA: Inferred from Direct Assay

C

From MGI

GO:0009897

external side of plasma membrane

MGI:MGI:1889050
PMID:8418208[1]

IDA: Inferred from Direct Assay

C

From MGI

GO:0009897

external side of plasma membrane

MGI:MGI:3028699
PMID:14662849[5]

IDA: Inferred from Direct Assay

C

From MGI

GO:0009897

external side of plasma membrane

MGI:MGI:3036943
PMID:14557413[6]

IDA: Inferred from Direct Assay

C

From MGI

GO:0009897

external side of plasma membrane

MGI:MGI:3581459
PMID:15909309[7]

IDA: Inferred from Direct Assay

C

From MGI

GO:0009897

external side of plasma membrane

MGI:MGI:67606
PMID:8041705[8]

IDA: Inferred from Direct Assay

C

From MGI

GO:0009897

external side of plasma membrane

MGI:MGI:77314
PMID:7477352[9]

IDA: Inferred from Direct Assay

C

From MGI

GO:0009897

external side of plasma membrane

MGI:MGI:77753
PMID:8566034[10]

IDA: Inferred from Direct Assay

C

From MGI

GO:0009897

external side of plasma membrane

MGI:MGI:80946
PMID:8666928[11]

IDA: Inferred from Direct Assay

C

From MGI

GO:0016064

immunoglobulin mediated immune response

MGI:MGI:1889050
PMID:8418208[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:1857186

P

From MGI

GO:0016446

somatic hypermutation of immunoglobulin genes

MGI:MGI:1889050
PMID:8418208[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:1857186

P

From MGI

GO:0019815

B cell receptor complex

MGI:MGI:1354084
PMID:10704460[4]

IDA: Inferred from Direct Assay

C

From MGI

GO:0019815

B cell receptor complex

MGI:MGI:1889050
PMID:8418208[1]

IDA: Inferred from Direct Assay

C

From MGI

GO:0019815

B cell receptor complex

MGI:MGI:3028699
PMID:14662849[5]

IDA: Inferred from Direct Assay

C

From MGI

GO:0019815

B cell receptor complex

MGI:MGI:3036943
PMID:14557413[6]

IDA: Inferred from Direct Assay

C

From MGI

GO:0019815

B cell receptor complex

MGI:MGI:77314
PMID:7477352[9]

IDA: Inferred from Direct Assay

C

From MGI

GO:0030890

positive regulation of B cell proliferation

MGI:MGI:80946
PMID:8666928[11]

IDA: Inferred from Direct Assay

P

From MGI

GO:0050776

regulation of immune response

MGI:MGI:1889050
PMID:8418208[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:1857186

P

From MGI

GO:0050776

regulation of immune response

MGI:MGI:87097
PMID:9133426[12]

IDA: Inferred from Direct Assay

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 1.4 1.5 Roes J & Rajewsky K (1993) Immunoglobulin D (IgD)-deficient mice reveal an auxiliary receptor function for IgD in antigen-mediated recruitment of B cells. J Exp Med 177: 45-55 PubMed GONUTS page
  2. Pani G et al. (1997) The motheaten mutation rescues B cell signaling and development in CD45-deficient mice. J Exp Med 186: 581-8 PubMed GONUTS page
  3. Moriggl R et al. (1999) Stat5 is required for IL-2-induced cell cycle progression of peripheral T cells. Immunity 10: 249-59 PubMed GONUTS page
  4. 4.0 4.1 Helgason CD et al. (2000) A dual role for Src homology 2 domain-containing inositol-5-phosphatase (SHIP) in immunity: aberrant development and enhanced function of b lymphocytes in ship -/- mice. J Exp Med 191: 781-94 PubMed GONUTS page
  5. 5.0 5.1 Kretschmer K et al. (2003) The selection of marginal zone B cells differs from that of B-1a cells. J Immunol 171: 6495-501 PubMed GONUTS page
  6. 6.0 6.1 Rahman ZS et al. (2003) Normal induction but attenuated progression of germinal center responses in BAFF and BAFF-R signaling-deficient mice. J Exp Med 198: 1157-69 PubMed GONUTS page
  7. Erlandsson L et al. (2005) Both the pre-BCR and the IL-7Ralpha are essential for expansion at the pre-BII cell stage in vivo. Eur J Immunol 35: 1969-76 PubMed GONUTS page
  8. Fujiwara H et al. (1994) The absence of IgE antibody-mediated augmentation of immune responses in CD23-deficient mice. Proc Natl Acad Sci U S A 91: 6835-9 PubMed GONUTS page
  9. 9.0 9.1 Turner M et al. (1995) Perinatal lethality and blocked B-cell development in mice lacking the tyrosine kinase Syk. Nature 378: 298-302 PubMed GONUTS page
  10. Kong YY et al. (1995) Differential requirements of CD45 for lymphocyte development and function. Eur J Immunol 25: 3431-6 PubMed GONUTS page
  11. 11.0 11.1 Byth KF et al. (1996) CD45-null transgenic mice reveal a positive regulatory role for CD45 in early thymocyte development, in the selection of CD4+CD8+ thymocytes, and B cell maturation. J Exp Med 183: 1707-18 PubMed GONUTS page
  12. Mendiratta SK et al. (1997) CD1d1 mutant mice are deficient in natural T cells that promptly produce IL-4. Immunity 6: 469-77 PubMed GONUTS page


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