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MGI:Igh-8

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Igh-8
Protein Name(s) immunoglobulin heavy chain 8 (heavy chain of IgG3),
External Links
MGI MGI:96450

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0001798

positive regulation of type IIa hypersensitivity

MGI:MGI:2177393
PMID:11901193[1]

IDA: Inferred from Direct Assay

P

From MGI

GO:0002455

humoral immune response mediated by circulating immunoglobulin

MGI:MGI:3037416
PMID:14988498[2]

IDA: Inferred from Direct Assay

P

From MGI

GO:0002455

humoral immune response mediated by circulating immunoglobulin

MGI:MGI:3620376
PMID:16492738[3]

IDA: Inferred from Direct Assay

P

From MGI

GO:0003823

antigen binding

MGI:MGI:1354084
PMID:10704460[4]

IDA: Inferred from Direct Assay

F

From MGI

GO:0003823

antigen binding

MGI:MGI:1889050
PMID:8418208[5]

IDA: Inferred from Direct Assay

F

From MGI

GO:0003823

antigen binding

MGI:MGI:2177393
PMID:11901193[1]

IDA: Inferred from Direct Assay

F

From MGI

GO:0003823

antigen binding

MGI:MGI:2679188
PMID:9551950[6]

IDA: Inferred from Direct Assay

F

From MGI

GO:0003823

antigen binding

MGI:MGI:2679189
PMID:11911823[7]

IDA: Inferred from Direct Assay

F

From MGI

GO:0003823

antigen binding

MGI:MGI:3037416
PMID:14988498[2]

IDA: Inferred from Direct Assay

F

From MGI

GO:0003823

antigen binding

MGI:MGI:3620376
PMID:16492738[3]

IDA: Inferred from Direct Assay

F

From MGI

GO:0006910

phagocytosis, recognition

MGI:MGI:2679188
PMID:9551950[6]

IDA: Inferred from Direct Assay

P

From MGI

GO:0006910

phagocytosis, recognition

MGI:MGI:2679189
PMID:11911823[7]

IDA: Inferred from Direct Assay

P

From MGI

GO:0006911

phagocytosis, engulfment

MGI:MGI:2177393
PMID:11901193[1]

IDA: Inferred from Direct Assay

P

From MGI

GO:0006911

phagocytosis, engulfment

MGI:MGI:2679188
PMID:9551950[6]

IDA: Inferred from Direct Assay

P

From MGI

GO:0006911

phagocytosis, engulfment

MGI:MGI:2679189
PMID:11911823[7]

IDA: Inferred from Direct Assay

P

From MGI

GO:0006958

complement activation, classical pathway

MGI:MGI:2177393
PMID:11901193[1]

IDA: Inferred from Direct Assay

P

From MGI

GO:0016064

immunoglobulin mediated immune response

MGI:MGI:1354084
PMID:10704460[4]

IDA: Inferred from Direct Assay

P

From MGI

GO:0016064

immunoglobulin mediated immune response

MGI:MGI:1889050
PMID:8418208[5]

IDA: Inferred from Direct Assay

P

From MGI

GO:0016064

immunoglobulin mediated immune response

MGI:MGI:2679189
PMID:11911823[7]

IDA: Inferred from Direct Assay

P

From MGI

GO:0042571

immunoglobulin complex, circulating

MGI:MGI:1354084
PMID:10704460[4]

IDA: Inferred from Direct Assay

C

From MGI

GO:0042571

immunoglobulin complex, circulating

MGI:MGI:1889050
PMID:8418208[5]

IDA: Inferred from Direct Assay

C

From MGI

GO:0042571

immunoglobulin complex, circulating

MGI:MGI:1926579
PMID:11057672[8]

IDA: Inferred from Direct Assay

C

From MGI

GO:0042571

immunoglobulin complex, circulating

MGI:MGI:2671681
PMID:9492004[9]

IDA: Inferred from Direct Assay

C

From MGI

GO:0042571

immunoglobulin complex, circulating

MGI:MGI:2679189
PMID:11911823[7]

IDA: Inferred from Direct Assay

C

From MGI

GO:0042571

immunoglobulin complex, circulating

MGI:MGI:3037416
PMID:14988498[2]

IDA: Inferred from Direct Assay

C

From MGI

GO:0042571

immunoglobulin complex, circulating

MGI:MGI:3039643
PMID:12867038[10]

IDA: Inferred from Direct Assay

C

From MGI

GO:0042571

immunoglobulin complex, circulating

MGI:MGI:3620376
PMID:16492738[3]

IDA: Inferred from Direct Assay

C

From MGI

GO:0042571

immunoglobulin complex, circulating

MGI:MGI:62368
PMID:7688139[11]

IDA: Inferred from Direct Assay

C

From MGI

GO:0050766

positive regulation of phagocytosis

MGI:MGI:2177393
PMID:11901193[1]

IDA: Inferred from Direct Assay

P

From MGI

GO:0050766

positive regulation of phagocytosis

MGI:MGI:2679188
PMID:9551950[6]

IDA: Inferred from Direct Assay

P

From MGI

GO:0050766

positive regulation of phagocytosis

MGI:MGI:2679189
PMID:11911823[7]

IDA: Inferred from Direct Assay

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 1.4 Azeredo da Silveira S et al. (2002) Complement activation selectively potentiates the pathogenicity of the IgG2b and IgG3 isotypes of a high affinity anti-erythrocyte autoantibody. J Exp Med 195: 665-72 PubMed GONUTS page
  2. 2.0 2.1 2.2 Castigli E et al. (2004) Impaired IgA class switching in APRIL-deficient mice. Proc Natl Acad Sci U S A 101: 3903-8 PubMed GONUTS page
  3. 3.0 3.1 3.2 Nishimura H & Strominger JL (2006) Involvement of a tissue-specific autoantibody in skin disorders of murine systemic lupus erythematosus and autoinflammatory diseases. Proc Natl Acad Sci U S A 103: 3292-7 PubMed GONUTS page
  4. 4.0 4.1 4.2 Helgason CD et al. (2000) A dual role for Src homology 2 domain-containing inositol-5-phosphatase (SHIP) in immunity: aberrant development and enhanced function of b lymphocytes in ship -/- mice. J Exp Med 191: 781-94 PubMed GONUTS page
  5. 5.0 5.1 5.2 Roes J & Rajewsky K (1993) Immunoglobulin D (IgD)-deficient mice reveal an auxiliary receptor function for IgD in antigen-mediated recruitment of B cells. J Exp Med 177: 45-55 PubMed GONUTS page
  6. 6.0 6.1 6.2 6.3 Gavin AL et al. (1998) Identification of the mouse IgG3 receptor: implications for antibody effector function at the interface between innate and adaptive immunity. J Immunol 160: 20-3 PubMed GONUTS page
  7. 7.0 7.1 7.2 7.3 7.4 7.5 Barnes N et al. (2002) FcgammaRI-deficient mice show multiple alterations to inflammatory and immune responses. Immunity 16: 379-89 PubMed GONUTS page
  8. Chen Q et al. (2000) Development of Th1-type immune responses requires the type I cytokine receptor TCCR. Nature 407: 916-20 PubMed GONUTS page
  9. Liljedahl M et al. (1998) Altered antigen presentation in mice lacking H2-O. Immunity 8: 233-43 PubMed GONUTS page
  10. Egawa T et al. (2003) Requirement for CARMA1 in antigen receptor-induced NF-kappa B activation and lymphocyte proliferation. Curr Biol 13: 1252-8 PubMed GONUTS page
  11. Shahinian A et al. (1993) Differential T cell costimulatory requirements in CD28-deficient mice. Science 261: 609-12 PubMed GONUTS page
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