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MGI:Igf2r
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Igf2r ( synonyms: CD222, CI-MPR, IGF-II/CI-MPR, M6P/IGF2R, mannose-6-phosphate receptor, cation independent, Mpr300 ) | |
| Protein Name(s) | insulin-like growth factor 2 receptor, | |
| External Links | ||
| MGI | MGI:96435 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0001889 |
liver development |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0001948 |
glycoprotein binding |
MGI:MGI:3769167 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0001948 |
glycoprotein binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0001965 |
G-protein alpha-subunit binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0001972 |
retinoic acid binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0004872 |
receptor activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0675 |
F |
From MGI |
||
| GO:0004930 |
G-protein coupled receptor activity |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0005215 |
transporter activity |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0005520 |
insulin-like growth factor binding |
MGI:MGI:2679358 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005537 |
mannose binding |
MGI:MGI:3769167 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0005615 |
extracellular space |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005624 |
membrane fraction |
MGI:MGI:3769167 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005624 |
membrane fraction |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:2667274 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005641 |
nuclear envelope lumen |
MGI:MGI:2667274 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
C |
From MGI |
|||
| GO:0005764 |
lysosome |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0458 |
C |
From MGI |
||
| GO:0005768 |
endosome |
MGI:MGI:3040541 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005768 |
endosome |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005770 |
late endosome |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0006810 |
transport |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0813 |
P |
From MGI |
||
| GO:0006810 |
transport |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0007186 |
G-protein coupled receptor signaling pathway |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0009986 |
cell surface |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0016020 |
membrane |
MGI:MGI:3769167 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0016021 |
integral to membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0812 |
C |
From MGI |
||
| GO:0016021 |
integral to membrane |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
C |
From MGI |
|||
| GO:0019899 |
enzyme binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0030139 |
endocytic vesicle |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0030140 |
trans-Golgi network transport vesicle |
MGI:MGI:3040541 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0031995 |
insulin-like growth factor II binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0032526 |
response to retinoic acid |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0042981 |
regulation of apoptotic process |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0043065 |
positive regulation of apoptotic process |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0048471 |
perinuclear region of cytoplasm |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0051219 |
phosphoprotein binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
|
colocalizes_with |
GO:0005802 |
trans-Golgi network |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 Lee SJ & Nathans D (1988) Proliferin secreted by cultured cells binds to mannose 6-phosphate receptors. J Biol Chem 263: 3521-7 PubMed GONUTS page
- ↑ McCusker RH & Novakofski J (2003) Zinc partitions insulin-like growth factors (IGFs) from soluble IGF binding protein (IGFBP)-5 to the cell surface receptors of BC3H-1 muscle cells. J Cell Physiol 197: 388-99 PubMed GONUTS page
- ↑ 3.0 3.1 Pantaleon M et al. (2003) The role of insulin-like growth factor II and its receptor in mouse preimplantation development. Reprod Fertil Dev 15: 37-45 PubMed GONUTS page
- ↑ 4.0 4.1 Seaman MN (2004) Cargo-selective endosomal sorting for retrieval to the Golgi requires retromer. J Cell Biol 165: 111-22 PubMed GONUTS page
