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MGI:Igf2
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Igf2 ( synonyms: Igf-2, Igf-II, M6pr, Mpr, Peg2 ) | |
| Protein Name(s) | insulin-like growth factor 2, | |
| External Links | ||
| MGI | MGI:96434 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0001503 |
ossification |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0892 |
P |
From MGI |
||
| GO:0001934 |
positive regulation of protein phosphorylation |
MGI:MGI:4438697 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0005158 |
insulin receptor binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0005159 |
insulin-like growth factor receptor binding |
MGI:MGI:2679358 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005179 |
hormone activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0372 |
F |
From MGI |
||
| GO:0005179 |
hormone activity |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:2679358 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:4422154 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005576 |
extracellular region |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0964 |
C |
From MGI |
||
| GO:0005576 |
extracellular region |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
C |
From MGI |
|||
| GO:0005615 |
extracellular space |
MGI:MGI:3806392 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005615 |
extracellular space |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005975 |
carbohydrate metabolic process |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0119 |
P |
From MGI |
||
| GO:0006006 |
glucose metabolic process |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0313 |
P |
From MGI |
||
| GO:0007613 |
memory |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0008083 |
growth factor activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0009887 |
organ morphogenesis |
MGI:MGI:2387729 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2677156 |
P |
From MGI |
||
| GO:0014070 |
response to organic cyclic compound |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0030546 |
receptor activator activity |
MGI:MGI:4438697 |
IMP: Inferred from Mutant Phenotype |
F |
From MGI |
|||
| GO:0031017 |
exocrine pancreas development |
MGI:MGI:2387729 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2677156 |
P |
From MGI |
||
| GO:0035094 |
response to nicotine |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0038028 |
insulin receptor signaling pathway via phosphatidylinositol 3-kinase cascade |
MGI:MGI:4438697 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0042104 |
positive regulation of activated T cell proliferation |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0042493 |
response to drug |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0043085 |
positive regulation of catalytic activity |
MGI:MGI:4438697 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0043410 |
positive regulation of MAPK cascade |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0043539 |
protein serine/threonine kinase activator activity |
MGI:MGI:4438697 |
IMP: Inferred from Mutant Phenotype |
F |
From MGI |
|||
| GO:0045725 |
positive regulation of glycogen biosynthetic process |
MGI:MGI:4438697 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0045840 |
positive regulation of mitosis |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0045944 |
positive regulation of transcription from RNA polymerase II promoter |
MGI:MGI:3806392 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:87986 |
P |
From MGI |
||
| GO:0046628 |
positive regulation of insulin receptor signaling pathway |
MGI:MGI:4438697 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0046628 |
positive regulation of insulin receptor signaling pathway |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0050731 |
positive regulation of peptidyl-tyrosine phosphorylation |
MGI:MGI:4438697 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0051146 |
striated muscle cell differentiation |
MGI:MGI:3806392 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:96440 |
P |
From MGI |
||
| GO:0051781 |
positive regulation of cell division |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0497 |
P |
From MGI |
||
| GO:0051897 |
positive regulation of protein kinase B signaling cascade |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0090031 |
positive regulation of steroid hormone biosynthetic process |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:2000467 |
positive regulation of glycogen (starch) synthase activity |
MGI:MGI:4438697 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 1.8 Liang L et al. (2010) Insulin-like growth factor 2 and the insulin receptor, but not insulin, regulate fetal hepatic glycogen synthesis. Endocrinology 151: 741-7 PubMed GONUTS page
- ↑ 2.0 2.1 McCusker RH & Novakofski J (2003) Zinc partitions insulin-like growth factors (IGFs) from soluble IGF binding protein (IGFBP)-5 to the cell surface receptors of BC3H-1 muscle cells. J Cell Physiol 197: 388-99 PubMed GONUTS page
- ↑ Datta K et al. (2009) NET37, a nuclear envelope transmembrane protein with glycosidase homology, is involved in myoblast differentiation. J Biol Chem 284: 29666-76 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 Ren H et al. (2008) IGFBP-5 regulates muscle cell differentiation by binding to IGF-II and switching on the IGF-II auto-regulation loop. J Cell Biol 182: 979-91 PubMed GONUTS page
- ↑ 5.0 5.1 Kido Y et al. (2002) Effects of mutations in the insulin-like growth factor signaling system on embryonic pancreas development and beta-cell compensation to insulin resistance. J Biol Chem 277: 36740-7 PubMed GONUTS page
