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MGI:Igbp1
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Igbp1 ( synonyms: alpha 4, p52, Pc52, Tap42 ) | |
| Protein Name(s) | immunoglobulin (CD79A) binding protein 1, | |
| External Links | ||
| MGI | MGI:1346500 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000122 |
negative regulation of transcription from RNA polymerase II promoter |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:4457251 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0963 |
C |
From MGI |
||
| GO:0008601 |
protein phosphatase type 2A regulator activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0009966 |
regulation of signal transduction |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0031434 |
mitogen-activated protein kinase kinase binding |
MGI:MGI:4457251 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0032873 |
negative regulation of stress-activated MAPK cascade |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0034612 |
response to tumor necrosis factor |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0035306 |
positive regulation of dephosphorylation |
MGI:MGI:3056248 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0035308 |
negative regulation of protein dephosphorylation |
MGI:MGI:4457251 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0035308 |
negative regulation of protein dephosphorylation |
MGI:MGI:4457259 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0042113 |
B cell activation |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0075 |
P |
From MGI |
||
| GO:0043066 |
negative regulation of apoptotic process |
MGI:MGI:3056248 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0043154 |
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0045944 |
positive regulation of transcription from RNA polymerase II promoter |
MGI:MGI:3056248 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0060632 |
regulation of microtubule-based movement |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0070555 |
response to interleukin-1 |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 Prickett TD & Brautigan DL (2007) Cytokine activation of p38 mitogen-activated protein kinase and apoptosis is opposed by alpha-4 targeting of protein phosphatase 2A for site-specific dephosphorylation of MEK3. Mol Cell Biol 27: 4217-27 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 Kong M et al. (2004) The PP2A-associated protein alpha4 is an essential inhibitor of apoptosis. Science 306: 695-8 PubMed GONUTS page
- ↑ Nanahoshi M et al. (1998) Regulation of protein phosphatase 2A catalytic activity by alpha4 protein and its yeast homolog Tap42. Biochem Biophys Res Commun 251: 520-6 PubMed GONUTS page
