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MGI:Ift172

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Ift172 ( synonyms: avc1, wim )
Protein Name(s) intraflagellar transport 172 homolog (Chlamydomonas),
External Links
MGI MGI:2682064

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000122

negative regulation of transcription from RNA polymerase II promoter

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_446244

P

From MGI

GO:0001841

neural tube formation

MGI:MGI:2679893
PMID:14603322[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2682066

P

From MGI

GO:0005515

protein binding

MGI:MGI:1926671
PMID:11062270[2]

IPI: Inferred from Physical Interaction

UniProtKB:Q61371

F

From MGI

GO:0005634

nucleus

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_446244

C

From MGI

GO:0005929

cilium

MGI:MGI:2679893
PMID:14603322[1]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005932

microtubule basal body

MGI:MGI:3703185
PMID:17312020[3]

ISO: Inferred from Sequence Orthology

UniProtKB:Q5DM57

C

From MGI

GO:0007224

smoothened signaling pathway

MGI:MGI:1926671
PMID:11062270[2]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0007275

multicellular organismal development

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0217

P

From MGI

GO:0007368

determination of left/right symmetry

MGI:MGI:3577662
PMID:15755804[4]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2682066

P

From MGI

GO:0008134

transcription factor binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_446244

F

From MGI

GO:0009434

microtubule-based flagellum

MGI:MGI:3703185
PMID:17312020[3]

ISO: Inferred from Sequence Orthology

UniProtKB:Q5DM57

C

From MGI

GO:0009953

dorsal/ventral pattern formation

MGI:MGI:2679893
PMID:14603322[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2682066

P

From MGI

GO:0009953

dorsal/ventral pattern formation

MGI:MGI:3577662
PMID:15755804[4]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2682066

P

From MGI

GO:0009953

dorsal/ventral pattern formation

MGI:MGI:3588600
PMID:16061793[5]

IGI: Inferred from Genetic Interaction

MGI:MGI:108075

P

From MGI

GO:0016485

protein processing

MGI:MGI:3588600
PMID:16061793[5]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2682066

P

From MGI

GO:0042384

cilium assembly

MGI:MGI:2679893
PMID:14603322[1]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0042995

cell projection

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0966

C

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 Huangfu D et al. (2003) Hedgehog signalling in the mouse requires intraflagellar transport proteins. Nature 426: 83-7 PubMed GONUTS page
  2. 2.0 2.1 Pazour GJ et al. (2000) Chlamydomonas IFT88 and its mouse homologue, polycystic kidney disease gene tg737, are required for assembly of cilia and flagella. J Cell Biol 151: 709-18 PubMed GONUTS page
  3. 3.0 3.1 Hou Y et al. (2007) Functional analysis of an individual IFT protein: IFT46 is required for transport of outer dynein arms into flagella. J Cell Biol 176: 653-65 PubMed GONUTS page
  4. 4.0 4.1 García-García MJ et al. (2005) Analysis of mouse embryonic patterning and morphogenesis by forward genetics. Proc Natl Acad Sci U S A 102: 5913-9 PubMed GONUTS page
  5. 5.0 5.1 Huangfu D & Anderson KV (2005) Cilia and Hedgehog responsiveness in the mouse. Proc Natl Acad Sci U S A 102: 11325-30 PubMed GONUTS page
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