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MGI:Ifng

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Ifng ( synonyms: Ifg, IFN-gamma )
Protein Name(s) interferon gamma,
External Links
MGI MGI:107656

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000060

protein import into nucleus, translocation

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P01579

P

From MGI

GO:0000122

negative regulation of transcription from RNA polymerase II promoter

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P01581

P

From MGI

GO:0001781

neutrophil apoptotic process

MGI:MGI:2673020
PMID:12925700[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:1857184

P

From MGI

GO:0002026

regulation of the force of heart contraction

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P01581

P

From MGI

GO:0002053

positive regulation of mesenchymal cell proliferation

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P01581

P

From MGI

GO:0002250

adaptive immune response

MGI:MGI:3829555
PMID:17277142[2]

IDA: Inferred from Direct Assay

P

From MGI

GO:0002302

CD8-positive, alpha-beta T cell differentiation involved in immune response

MGI:MGI:3829555
PMID:17277142[2]

IDA: Inferred from Direct Assay

P

From MGI

GO:0003340

negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P01581

P

From MGI

GO:0005125

cytokine activity

MGI:MGI:2664488
PMID:11911824[3]

IDA: Inferred from Direct Assay

F

From MGI

GO:0005125

cytokine activity

MGI:MGI:2673020
PMID:12925700[1]

IDA: Inferred from Direct Assay

F

From MGI

GO:0005125

cytokine activity

MGI:MGI:3033882
PMID:11027433[4]

IDA: Inferred from Direct Assay

F

From MGI

GO:0005125

cytokine activity

MGI:MGI:3051174
PMID:15240719[5]

IDA: Inferred from Direct Assay

F

From MGI

GO:0005133

interferon-gamma receptor binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR002069

F

From MGI

GO:0005576

extracellular region

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0964

C

From MGI

GO:0005576

extracellular region

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR002069

C

From MGI

GO:0005615

extracellular space

MGI:MGI:1332382
PMID:10072077[6]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005615

extracellular space

MGI:MGI:1926579
PMID:11057672[7]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005615

extracellular space

MGI:MGI:2176422
PMID:11894098[8]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005615

extracellular space

MGI:MGI:3050756
PMID:15220916[9]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005615

extracellular space

MGI:MGI:3051177
PMID:15240714[10]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005615

extracellular space

MGI:MGI:3510555
PMID:11728336[11]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005615

extracellular space

MGI:MGI:3653161
PMID:9348310[12]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005615

extracellular space

MGI:MGI:3693968
PMID:16769892[13]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005615

extracellular space

MGI:MGI:3695768
PMID:16275384[14]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005615

extracellular space

MGI:MGI:3813999
PMID:17082577[15]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005615

extracellular space

MGI:MGI:3823129
PMID:18997793[16]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005615

extracellular space

MGI:MGI:3829555
PMID:17277142[2]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005615

extracellular space

MGI:MGI:3829555
PMID:17277142[2]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005615

extracellular space

MGI:MGI:3839525
PMID:19139201[17]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005615

extracellular space

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P01581

C

From MGI

GO:0005615

extracellular space

MGI:MGI:4838368
PMID:20706986[18]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005615

extracellular space

MGI:MGI:5004747
PMID:21460847[19]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005622

intracellular

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P01579

C

From MGI

GO:0006355

regulation of transcription, DNA-dependent

MGI:MGI:2385392
PMID:12050152[20]

IDA: Inferred from Direct Assay

P

From MGI

GO:0006915

apoptotic process

MGI:MGI:2154458

ISO: Inferred from Sequence Orthology

UniProtKB:P01579

P

From MGI

GO:0006925

inflammatory cell apoptotic process

MGI:MGI:3027059
PMID:11457893[21]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0006955

immune response

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR002069

P

From MGI

GO:0006959

humoral immune response

MGI:MGI:3829555
PMID:17277142[2]

IDA: Inferred from Direct Assay

P

From MGI

GO:0007050

cell cycle arrest

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P01579

P

From MGI

GO:0008285

negative regulation of cell proliferation

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P01581

P

From MGI

GO:0009615

response to virus

MGI:MGI:3621255
PMID:16280321[22]

ISO: Inferred from Sequence Orthology

UniProtKB:P01579

P

From MGI

GO:0009897

external side of plasma membrane

MGI:MGI:3700858
PMID:16177108[23]

IDA: Inferred from Direct Assay

C

From MGI

GO:0009897

external side of plasma membrane

MGI:MGI:3718932
PMID:17658279[24]

IDA: Inferred from Direct Assay

C

From MGI

GO:0009897

external side of plasma membrane

MGI:MGI:4454353
PMID:20399120[25]

IDA: Inferred from Direct Assay

C

From MGI

GO:0009897

external side of plasma membrane

MGI:MGI:4838928
PMID:20956546[26]

IDA: Inferred from Direct Assay

C

From MGI

GO:0009897

external side of plasma membrane

MGI:MGI:4887510
PMID:21217760[27]

IDA: Inferred from Direct Assay

C

From MGI

GO:0009897

external side of plasma membrane

MGI:MGI:5013872
PMID:21606376[28]

IDA: Inferred from Direct Assay

C

From MGI

GO:0009897

external side of plasma membrane

MGI:MGI:5085959
PMID:21709260[29]

IDA: Inferred from Direct Assay

C

From MGI

GO:0009897

external side of plasma membrane

MGI:MGI:5287957
PMID:21613615[30]

IDA: Inferred from Direct Assay

C

From MGI

GO:0019882

antigen processing and presentation

MGI:MGI:3054461
PMID:15356141[31]

IDA: Inferred from Direct Assay

P

From MGI

GO:0030593

neutrophil chemotaxis

MGI:MGI:2673020
PMID:12925700[1]

IDA: Inferred from Direct Assay

P

From MGI

GO:0030593

neutrophil chemotaxis

MGI:MGI:2673020
PMID:12925700[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:1857184

P

From MGI

GO:0030968

endoplasmic reticulum unfolded protein response

MGI:MGI:3583403
PMID:15911877[32]

IDA: Inferred from Direct Assay

P

From MGI

GO:0031642

negative regulation of myelination

MGI:MGI:3583403
PMID:15911877[32]

IDA: Inferred from Direct Assay

P

From MGI

GO:0032224

positive regulation of synaptic transmission, cholinergic

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P01581

P

From MGI

GO:0032700

negative regulation of interleukin-17 production

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P01579

P

From MGI

GO:0032735

positive regulation of interleukin-12 production

MGI:MGI:3653161
PMID:9348310[12]

IDA: Inferred from Direct Assay

P

From MGI

GO:0032735

positive regulation of interleukin-12 production

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P01579

P

From MGI

GO:0032747

positive regulation of interleukin-23 production

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P01579

P

From MGI

GO:0032760

positive regulation of tumor necrosis factor production

MGI:MGI:4942276
PMID:2502420[33]

IDA: Inferred from Direct Assay

P

From MGI

GO:0032760

positive regulation of tumor necrosis factor production

MGI:MGI:4943415
PMID:1845803[34]

IDA: Inferred from Direct Assay

P

From MGI

GO:0033141

positive regulation of peptidyl-serine phosphorylation of STAT protein

MGI:MGI:3621255
PMID:16280321[22]

ISO: Inferred from Sequence Orthology

UniProtKB:P01579

P

From MGI

GO:0033141

positive regulation of peptidyl-serine phosphorylation of STAT protein

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P01581

P

From MGI

GO:0034393

positive regulation of smooth muscle cell apoptotic process

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P01579

P

From MGI

GO:0040008

regulation of growth

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0341

P

From MGI

GO:0042102

positive regulation of T cell proliferation

MGI:MGI:3621255
PMID:16280321[22]

IDA: Inferred from Direct Assay

P

From MGI

GO:0042511

positive regulation of tyrosine phosphorylation of Stat1 protein

MGI:MGI:3621255
PMID:16280321[22]

ISO: Inferred from Sequence Orthology

UniProtKB:P01579

P

From MGI

GO:0042511

positive regulation of tyrosine phosphorylation of Stat1 protein

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P01581

P

From MGI

GO:0042511

positive regulation of tyrosine phosphorylation of Stat1 protein

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P01579

P

From MGI

GO:0042742

defense response to bacterium

MGI:MGI:3051174
PMID:15240719[5]

IDA: Inferred from Direct Assay

P

From MGI

GO:0042832

defense response to protozoan

MGI:MGI:3653161
PMID:9348310[12]

IMP: Inferred from Mutant Phenotype

MGI:MGI:1857184

P

From MGI

GO:0044130

negative regulation of growth of symbiont in host

MGI:MGI:3653161
PMID:9348310[12]

IMP: Inferred from Mutant Phenotype

MGI:MGI:1857184

P

From MGI

GO:0044146

negative regulation of growth of symbiont involved in interaction with host

MGI:MGI:3653161
PMID:9348310[12]

IDA: Inferred from Direct Assay

P

From MGI

GO:0045080

positive regulation of chemokine biosynthetic process

MGI:MGI:2673020
PMID:12925700[1]

IDA: Inferred from Direct Assay

P

From MGI

GO:0045080

positive regulation of chemokine biosynthetic process

MGI:MGI:2673020
PMID:12925700[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:1857184

P

From MGI

GO:0045084

positive regulation of interleukin-12 biosynthetic process

MGI:MGI:2679145
PMID:14568984[35]

IDA: Inferred from Direct Assay

P

From MGI

GO:0045348

positive regulation of MHC class II biosynthetic process

MGI:MGI:3033882
PMID:11027433[4]

IDA: Inferred from Direct Assay

P

From MGI

GO:0045348

positive regulation of MHC class II biosynthetic process

MGI:MGI:4942276
PMID:2502420[33]

IDA: Inferred from Direct Assay

P

From MGI

GO:0045348

positive regulation of MHC class II biosynthetic process

MGI:MGI:4942277
PMID:2493384[36]

IDA: Inferred from Direct Assay

P

From MGI

GO:0045348

positive regulation of MHC class II biosynthetic process

MGI:MGI:4943415
PMID:1845803[34]

IDA: Inferred from Direct Assay

P

From MGI

GO:0045410

positive regulation of interleukin-6 biosynthetic process

MGI:MGI:2673020
PMID:12925700[1]

IDA: Inferred from Direct Assay

P

From MGI

GO:0045410

positive regulation of interleukin-6 biosynthetic process

MGI:MGI:2673020
PMID:12925700[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:1857184

P

From MGI

GO:0045429

positive regulation of nitric oxide biosynthetic process

MGI:MGI:1930064
PMID:11168643[37]

IDA: Inferred from Direct Assay

P

From MGI

GO:0045429

positive regulation of nitric oxide biosynthetic process

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P01579

P

From MGI

GO:0045666

positive regulation of neuron differentiation

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P01581

P

From MGI

GO:0045672

positive regulation of osteoclast differentiation

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P01579

P

From MGI

GO:0045785

positive regulation of cell adhesion

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P01581

P

From MGI

GO:0045893

positive regulation of transcription, DNA-dependent

MGI:MGI:2679145
PMID:14568984[35]

IDA: Inferred from Direct Assay

P

From MGI

GO:0045944

positive regulation of transcription from RNA polymerase II promoter

MGI:MGI:4412460
PMID:18025219[38]

IDA: Inferred from Direct Assay

P

From MGI

GO:0045944

positive regulation of transcription from RNA polymerase II promoter

MGI:MGI:4412460
PMID:18025219[38]

IGI: Inferred from Genetic Interaction

MGI:MGI:104798

P

From MGI

GO:0048304

positive regulation of isotype switching to IgG isotypes

MGI:MGI:2670820
PMID:12882831[39]

IDA: Inferred from Direct Assay

P

From MGI

GO:0048662

negative regulation of smooth muscle cell proliferation

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P01579

P

From MGI

GO:0050718

positive regulation of interleukin-1 beta secretion

MGI:MGI:2673020
PMID:12925700[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:1857184

P

From MGI

GO:0050776

regulation of immune response

MGI:MGI:2670820
PMID:12882831[39]

IDA: Inferred from Direct Assay

P

From MGI

GO:0050796

regulation of insulin secretion

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P01579

P

From MGI

GO:0051044

positive regulation of membrane protein ectodomain proteolysis

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P01579

P

From MGI

GO:0051607

defense response to virus

MGI:MGI:4431293
PMID:20064371[40]

IDA: Inferred from Direct Assay

P

From MGI

GO:0051712

positive regulation of killing of cells of other organism

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P01579

P

From MGI

GO:0060550

positive regulation of fructose 1,6-bisphosphate 1-phosphatase activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P01579

P

From MGI

GO:0060552

positive regulation of fructose 1,6-bisphosphate metabolic process

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P01579

P

From MGI

GO:0060557

positive regulation of vitamin D biosynthetic process

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P01579

P

From MGI

GO:0060559

positive regulation of calcidiol 1-monooxygenase activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P01579

P

From MGI

GO:0071222

cellular response to lipopolysaccharide

MGI:MGI:3821815
PMID:18791161[41]

IDA: Inferred from Direct Assay

P

From MGI

GO:0071351

cellular response to interleukin-18

MGI:MGI:4355633
PMID:19666510[42]

IDA: Inferred from Direct Assay

P

From MGI

GO:0072308

negative regulation of metanephric nephron tubule epithelial cell differentiation

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P01581

P

From MGI

GO:2000309

positive regulation of tumor necrosis factor (ligand) superfamily member 11 production

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P01579

P

From MGI


edit table

Notes

References

See Help:References for how to manage references in GONUTS.
  1. ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 1.8 McLoughlin RM et al. (2003) Interplay between IFN-gamma and IL-6 signaling governs neutrophil trafficking and apoptosis during acute inflammation. J Clin Invest 112: 598-607 PubMed GONUTS page
  2. ↑ 2.0 2.1 2.2 2.3 2.4 Hervas-Stubbs S et al. (2007) Insect baculoviruses strongly potentiate adaptive immune responses by inducing type I IFN. J Immunol 178: 2361-9 PubMed GONUTS page
  3. ↑ Ioan-Facsinay A et al. (2002) FcgammaRI (CD64) contributes substantially to severity of arthritis, hypersensitivity responses, and protection from bacterial infection. Immunity 16: 391-402 PubMed GONUTS page
  4. ↑ 4.0 4.1 Walter W et al. (2000) MHC class II antigen presentation pathway in murine tumours: tumour evasion from immunosurveillance? Br J Cancer 83: 1192-201 PubMed GONUTS page
  5. ↑ 5.0 5.1 Schiavoni G et al. (2004) Type I IFN protects permissive macrophages from Legionella pneumophila infection through an IFN-gamma-independent pathway. J Immunol 173: 1266-75 PubMed GONUTS page
  6. ↑ Moriggl R et al. (1999) Stat5 is required for IL-2-induced cell cycle progression of peripheral T cells. Immunity 10: 249-59 PubMed GONUTS page
  7. ↑ Chen Q et al. (2000) Development of Th1-type immune responses requires the type I cytokine receptor TCCR. Nature 407: 916-20 PubMed GONUTS page
  8. ↑ Kobayashi K et al. (2002) RICK/Rip2/CARDIAK mediates signalling for receptors of the innate and adaptive immune systems. Nature 416: 194-9 PubMed GONUTS page
  9. ↑ Watanabe T et al. (2004) NOD2 is a negative regulator of Toll-like receptor 2-mediated T helper type 1 responses. Nat Immunol 5: 800-8 PubMed GONUTS page
  10. ↑ McKee AS & Pearce EJ (2004) CD25+CD4+ cells contribute to Th2 polarization during helminth infection by suppressing Th1 response development. J Immunol 173: 1224-31 PubMed GONUTS page
  11. ↑ Allenspach EJ et al. (2001) ERM-dependent movement of CD43 defines a novel protein complex distal to the immunological synapse. Immunity 15: 739-50 PubMed GONUTS page
  12. ↑ 12.0 12.1 12.2 12.3 12.4 Scharton-Kersten T et al. (1997) Interferon consensus sequence binding protein-deficient mice display impaired resistance to intracellular infection due to a primary defect in interleukin 12 p40 induction. J Exp Med 186: 1523-34 PubMed GONUTS page
  13. ↑ Chae WJ et al. (2006) The mutant leucine-zipper domain impairs both dimerization and suppressive function of Foxp3 in T cells. Proc Natl Acad Sci U S A 103: 9631-6 PubMed GONUTS page
  14. ↑ Lin W et al. (2005) Allergic dysregulation and hyperimmunoglobulinemia E in Foxp3 mutant mice. J Allergy Clin Immunol 116: 1106-15 PubMed GONUTS page
  15. ↑ Kim PJ et al. (2006) GATA-3 regulates the development and function of invariant NKT cells. J Immunol 177: 6650-9 PubMed GONUTS page
  16. ↑ Dardalhon V et al. (2008) IL-4 inhibits TGF-beta-induced Foxp3+ T cells and, together with TGF-beta, generates IL-9+ IL-10+ Foxp3(-) effector T cells. Nat Immunol 9: 1347-55 PubMed GONUTS page
  17. ↑ Deshmukh HS et al. (2009) Critical role of NOD2 in regulating the immune response to Staphylococcus aureus. Infect Immun 77: 1376-82 PubMed GONUTS page
  18. ↑ Wang L et al. (2010) The sequential activity of Gata3 and Thpok is required for the differentiation of CD1d-restricted CD4+ NKT cells. Eur J Immunol 40: 2385-90 PubMed GONUTS page
  19. ↑ Motomura Y et al. (2011) The transcription factor E4BP4 regulates the production of IL-10 and IL-13 in CD4+ T cells. Nat Immunol 12: 450-9 PubMed GONUTS page
  20. ↑ Hu J et al. (2002) A novel transactivating factor that regulates interferon-gamma-dependent gene expression. J Biol Chem 277: 30253-63 PubMed GONUTS page
  21. ↑ Collazo CM et al. (2001) Inactivation of LRG-47 and IRG-47 reveals a family of interferon gamma-inducible genes with essential, pathogen-specific roles in resistance to infection. J Exp Med 194: 181-8 PubMed GONUTS page
  22. ↑ 22.0 22.1 22.2 22.3 Shang L & Tomasi TB (2006) The heat shock protein 90-CDC37 chaperone complex is required for signaling by types I and II interferons. J Biol Chem 281: 1876-84 PubMed GONUTS page
  23. ↑ Nishimura H et al. (2005) A novel role of CD30/CD30 ligand signaling in the generation of long-lived memory CD8+ T cells. J Immunol 175: 4627-34 PubMed GONUTS page
  24. ↑ Amsen D et al. (2007) Direct regulation of Gata3 expression determines the T helper differentiation potential of Notch. Immunity 27: 89-99 PubMed GONUTS page
  25. ↑ Yagi R et al. (2010) The transcription factor GATA3 actively represses RUNX3 protein-regulated production of interferon-gamma. Immunity 32: 507-17 PubMed GONUTS page
  26. ↑ Onodera A et al. (2010) STAT6-mediated displacement of polycomb by trithorax complex establishes long-term maintenance of GATA3 expression in T helper type 2 cells. J Exp Med 207: 2493-506 PubMed GONUTS page
  27. ↑ Li Z et al. (2011) ECM1 controls T(H)2 cell egress from lymph nodes through re-expression of S1P(1). Nat Immunol 12: 178-85 PubMed GONUTS page
  28. ↑ Day EB et al. (2011) Structural basis for enabling T-cell receptor diversity within biased virus-specific CD8+ T-cell responses. Proc Natl Acad Sci U S A 108: 9536-41 PubMed GONUTS page
  29. ↑ Sharma S et al. (2011) Dephosphorylation of the nuclear factor of activated T cells (NFAT) transcription factor is regulated by an RNA-protein scaffold complex. Proc Natl Acad Sci U S A 108: 11381-6 PubMed GONUTS page
  30. ↑ Stellato C et al. (2011) Coordinate regulation of GATA-3 and Th2 cytokine gene expression by the RNA-binding protein HuR. J Immunol 187: 441-9 PubMed GONUTS page
  31. ↑ Basler M et al. (2004) Immunoproteasomes down-regulate presentation of a subdominant T cell epitope from lymphocytic choriomeningitis virus. J Immunol 173: 3925-34 PubMed GONUTS page
  32. ↑ 32.0 32.1 Lin W et al. (2005) Endoplasmic reticulum stress modulates the response of myelinating oligodendrocytes to the immune cytokine interferon-gamma. J Cell Biol 169: 603-12 PubMed GONUTS page
  33. ↑ 33.0 33.1 Celada A et al. (1989) Interferon-gamma activates multiple pathways to regulate the expression of the genes for major histocompatibility class II I-A beta, tumor necrosis factor and complement component C3 in mouse macrophages. Eur J Immunol 19: 1103-9 PubMed GONUTS page
  34. ↑ 34.0 34.1 Celada A & Maki RA (1991) IFN-gamma induces the expression of the genes for MHC class II I-A beta and tumor necrosis factor through a protein kinase C-independent pathway. J Immunol 146: 114-20 PubMed GONUTS page
  35. ↑ 35.0 35.1 Liu J et al. (2003) Differential regulation of interleukin (IL)-12 p35 and p40 gene expression and interferon (IFN)-gamma-primed IL-12 production by IFN regulatory factor 1. J Exp Med 198: 1265-76 PubMed GONUTS page
  36. ↑ Celada A & Maki RA (1989) The expression of I-A correlates with the uptake of interferon-gamma by macrophages. Eur J Immunol 19: 205-8 PubMed GONUTS page
  37. ↑ Bune AJ et al. (2001) Mice lacking tartrate-resistant acid phosphatase (Acp 5) have disordered macrophage inflammatory responses and reduced clearance of the pathogen, Staphylococcus aureus. Immunology 102: 103-13 PubMed GONUTS page
  38. ↑ 38.0 38.1 Degrandi D et al. (2007) Extensive characterization of IFN-induced GTPases mGBP1 to mGBP10 involved in host defense. J Immunol 179: 7729-40 PubMed GONUTS page
  39. ↑ 39.0 39.1 Gerth AJ et al. (2003) T-bet regulates T-independent IgG2a class switching. Int Immunol 15: 937-44 PubMed GONUTS page
  40. ↑ Brass AL et al. (2009) The IFITM proteins mediate cellular resistance to influenza A H1N1 virus, West Nile virus, and dengue virus. Cell 139: 1243-54 PubMed GONUTS page
  41. ↑ Dai R et al. (2008) Suppression of LPS-induced Interferon-gamma and nitric oxide in splenic lymphocytes by select estrogen-regulated microRNAs: a novel mechanism of immune modulation. Blood 112: 4591-7 PubMed GONUTS page
  42. ↑ Guo L et al. (2009) IL-1 family members and STAT activators induce cytokine production by Th2, Th17, and Th1 cells. Proc Natl Acad Sci U S A 106: 13463-8 PubMed GONUTS page
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