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MGI:Ifnb1

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Ifnb1 ( synonyms: Ifb, IFN-beta, IFNB, interferon beta 1, fibroblast )
Protein Name(s) interferon beta 1, fibroblast,
External Links
MGI MGI:107657

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0002250

adaptive immune response

MGI:MGI:3829555
PMID:17277142[1]

IDA: Inferred from Direct Assay

P

From MGI

GO:0003714

transcription corepressor activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P01574

F

From MGI

GO:0005125

cytokine activity

MGI:MGI:3051174
PMID:15240719[2]

IDA: Inferred from Direct Assay

F

From MGI

GO:0005126

cytokine receptor binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR000471

F

From MGI

GO:0005576

extracellular region

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0964

C

From MGI

GO:0005576

extracellular region

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR000471

C

From MGI

GO:0005615

extracellular space

MGI:MGI:3829555
PMID:17277142[1]

IDA: Inferred from Direct Assay

C

From MGI

GO:0006917

induction of apoptosis

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P01574

P

From MGI

GO:0006919

activation of cysteine-type endopeptidase activity involved in apoptotic process

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P01574

P

From MGI

GO:0006952

defense response

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR000471

P

From MGI

GO:0006959

humoral immune response

MGI:MGI:3829555
PMID:17277142[1]

IDA: Inferred from Direct Assay

P

From MGI

GO:0009615

response to virus

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0051

P

From MGI

GO:0032897

negative regulation of viral transcription

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P01574

P

From MGI

GO:0042742

defense response to bacterium

MGI:MGI:3051174
PMID:15240719[2]

IDA: Inferred from Direct Assay

P

From MGI

GO:0045071

negative regulation of viral genome replication

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P01574

P

From MGI

GO:0045581

negative regulation of T cell differentiation

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P01574

P

From MGI

GO:0045944

positive regulation of transcription from RNA polymerase II promoter

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P01574

P

From MGI

GO:0051607

defense response to virus

MGI:MGI:3829555
PMID:17277142[1]

IDA: Inferred from Direct Assay

P

From MGI

GO:0051607

defense response to virus

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P01574

P

From MGI

GO:0071360

cellular response to exogenous dsRNA

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P01574

P

From MGI

GO:2000552

negative regulation of T-helper 2 cell cytokine production

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P01574

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 Hervas-Stubbs S et al. (2007) Insect baculoviruses strongly potentiate adaptive immune responses by inducing type I IFN. J Immunol 178: 2361-9 PubMed GONUTS page
  2. 2.0 2.1 Schiavoni G et al. (2004) Type I IFN protects permissive macrophages from Legionella pneumophila infection through an IFN-gamma-independent pathway. J Immunol 173: 1266-75 PubMed GONUTS page
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