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MGI:Ifnar1

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Ifnar1 ( synonyms: Ifar, IFN-alpha/betaR, Ifrc )
Protein Name(s) interferon (alpha and beta) receptor 1,
External Links
MGI MGI:107658

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0004637

phosphoribosylamine-glycine ligase activity

MGI:MGI:2152096

IEA: Inferred from Electronic Annotation

EC:6.3.4.13

F

From MGI

GO:0004872

receptor activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0675

F

From MGI

GO:0004904

interferon receptor activity

MGI:MGI:3590365
PMID:16139798[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:1930950

F

From MGI

GO:0008152

metabolic process

MGI:MGI:2152096

IEA: Inferred from Electronic Annotation

EC:6.3.4.13

P

From MGI

GO:0016020

membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0472

C

From MGI

GO:0016021

integral to membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0812

C

From MGI

GO:0032729

positive regulation of interferon-gamma production

MGI:MGI:3708392
PMID:17164250[2]

IGI: Inferred from Genetic Interaction

MGI:MGI:96242

P

From MGI

GO:0042110

T cell activation

MGI:MGI:3708392
PMID:17164250[2]

IGI: Inferred from Genetic Interaction

MGI:MGI:96242

P

From MGI

GO:0045351

type I interferon biosynthetic process

MGI:MGI:3575992
PMID:15800576[3]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0051607

defense response to virus

MGI:MGI:3829555
PMID:17277142[4]

IMP: Inferred from Mutant Phenotype

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Giannakopoulos NV et al. (2005) Proteomic identification of proteins conjugated to ISG15 in mouse and human cells. Biochem Biophys Res Commun 336: 496-506 PubMed GONUTS page
  2. 2.0 2.1 Osterloh A et al. (2007) Synergistic and differential modulation of immune responses by Hsp60 and lipopolysaccharide. J Biol Chem 282: 4669-80 PubMed GONUTS page
  3. Honda K et al. (2005) IRF-7 is the master regulator of type-I interferon-dependent immune responses. Nature 434: 772-7 PubMed GONUTS page
  4. Hervas-Stubbs S et al. (2007) Insect baculoviruses strongly potentiate adaptive immune responses by inducing type I IFN. J Immunol 178: 2361-9 PubMed GONUTS page
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