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MGI:Idh2

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Idh2 ( synonyms: Idh-2, IDPm )
Protein Name(s) isocitrate dehydrogenase 2 (NADP+), mitochondrial,
External Links
MGI MGI:96414

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000287

magnesium ion binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR019818

F

From MGI

GO:0004450

isocitrate dehydrogenase (NADP+) activity

MGI:MGI:55148
PMID:7323947[1]

IDA: Inferred from Direct Assay

F

From MGI

GO:0004450

isocitrate dehydrogenase (NADP+) activity

MGI:MGI:80465
PMID:8867815[2]

IDA: Inferred from Direct Assay

F

From MGI

GO:0005739

mitochondrion

MGI:MGI:2682130
PMID:14651853[3]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005739

mitochondrion

MGI:MGI:3852644
PMID:18614015[4]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005739

mitochondrion

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:B4DFL2

C

From MGI

GO:0005743

mitochondrial inner membrane

MGI:MGI:3590069
PMID:12865426[5]

IDA: Inferred from Direct Assay

C

From MGI

GO:0006097

glyoxylate cycle

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0329

P

From MGI

GO:0006099

tricarboxylic acid cycle

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0816

P

From MGI

GO:0006102

isocitrate metabolic process

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR004790

P

From MGI

GO:0006950

response to stress

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0346

P

From MGI

GO:0016491

oxidoreductase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0560

F

From MGI

GO:0016616

oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR019818
InterPro:IPR024084

F

From MGI

GO:0046872

metal ion binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0479

F

From MGI

GO:0051287

NAD binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR019818

F

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Stallings RL & Siciliano MJ (1981) Confirmational, provisional, and/or regional assignment of 15 enzyme loci onto Chinese hamster autosomes 1, 2, and 7. Somatic Cell Genet 7: 683-98 PubMed GONUTS page
  2. Yang L et al. (1996) Molecular cloning of the cDNA of mouse mitochondrial NADP-dependent isocitrate dehydrogenase and the expression of the gene during lymphocyte activation. J Cell Biochem 60: 400-10 PubMed GONUTS page
  3. Mootha VK et al. (2003) Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria. Cell 115: 629-40 PubMed GONUTS page
  4. Pagliarini DJ et al. (2008) A mitochondrial protein compendium elucidates complex I disease biology. Cell 134: 112-23 PubMed GONUTS page
  5. Da Cruz S et al. (2003) Proteomic analysis of the mouse liver mitochondrial inner membrane. J Biol Chem 278: 41566-71 PubMed GONUTS page
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