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MGI:Hus1
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Hus1 | |
| Protein Name(s) | Hus1 homolog (S. pombe), | |
| External Links | ||
| MGI | MGI:1277962 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000077 |
DNA damage checkpoint |
MGI:MGI:2449744 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1927769 |
P |
From MGI |
||
| GO:0000077 |
DNA damage checkpoint |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0000724 |
double-strand break repair via homologous recombination |
MGI:MGI:3690191 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0001932 |
regulation of protein phosphorylation |
MGI:MGI:3690176 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005730 |
nucleolus |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0963 |
C |
From MGI |
||
| GO:0005794 |
Golgi apparatus |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0006281 |
DNA repair |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0234 |
P |
From MGI |
||
| GO:0006468 |
protein phosphorylation |
MGI:MGI:2156961 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0006468 |
protein phosphorylation |
MGI:MGI:2449744 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1927769 |
P |
From MGI |
||
| GO:0006974 |
response to DNA damage stimulus |
MGI:MGI:2156961 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0008156 |
negative regulation of DNA replication |
MGI:MGI:3027697 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0009411 |
response to UV |
MGI:MGI:2156961 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0009411 |
response to UV |
MGI:MGI:2449744 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1927769 |
P |
From MGI |
||
| GO:0009790 |
embryo development |
MGI:MGI:3582004 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0031575 |
mitotic cell cycle G1/S transition checkpoint |
MGI:MGI:3027697 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0071479 |
cellular response to ionizing radiation |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 Weiss RS et al. (2003) Critical role for mouse Hus1 in an S-phase DNA damage cell cycle checkpoint. Mol Cell Biol 23: 791-803 PubMed GONUTS page
- ↑ Wang X et al. (2006) The effect of Hus1 on ionizing radiation sensitivity is associated with homologous recombination repair but is independent of nonhomologous end-joining. Oncogene 25: 1980-3 PubMed GONUTS page
- ↑ Jiang K et al. (2003) Regulation of Chk1 includes chromatin association and 14-3-3 binding following phosphorylation on Ser-345. J Biol Chem 278: 25207-17 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 Weiss RS et al. (2002) Hus1 acts upstream of chk1 in a mammalian DNA damage response pathway. Curr Biol 12: 73-7 PubMed GONUTS page
- ↑ 5.0 5.1 Wang X et al. (2004) Involvement of Hus1 in the chain elongation step of DNA replication after exposure to camptothecin or ionizing radiation. Nucleic Acids Res 32: 767-75 PubMed GONUTS page
- ↑ Levitt PS et al. (2005) Conditional inactivation of the mouse Hus1 cell cycle checkpoint gene. Genomics 86: 212-24 PubMed GONUTS page
