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MGI:Hsp90ab1

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Hsp90ab1 ( synonyms: C81438, Hsp84, Hsp84-1, Hsp90, Hspcb )
Protein Name(s) heat shock protein 90 alpha (cytosolic), class B member 1,
External Links
MGI MGI:96247

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000166

nucleotide binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0547

F

From MGI

GO:0001890

placenta development

MGI:MGI:1349344
PMID:10654595[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:1857893

P

From MGI

GO:0002134

UTP binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P34058

F

From MGI

GO:0002135

CTP binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P34058

F

From MGI

GO:0005515

protein binding

MGI:MGI:2158896
PMID:11751894[2]

IPI: Inferred from Physical Interaction

UniProtKB:P06537

F

From MGI

GO:0005515

protein binding

MGI:MGI:2177855
PMID:11809749[3]

IPI: Inferred from Physical Interaction

UniProtKB:Q8VII8

F

From MGI

GO:0005524

ATP binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P34058

F

From MGI

GO:0005525

GTP binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P34058

F

From MGI

GO:0005622

intracellular

MGI:MGI:86714
PMID:9122205[4]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005625

soluble fraction

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P34058

C

From MGI

GO:0005737

cytoplasm

MGI:MGI:3758968
PMID:17908927[5]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005737

cytoplasm

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P34058

C

From MGI

GO:0005739

mitochondrion

MGI:MGI:2682130
PMID:14651853[6]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005829

cytosol

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P34058

C

From MGI

GO:0006457

protein folding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR019805
InterPro:IPR001404

P

From MGI

GO:0006950

response to stress

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0346

P

From MGI

GO:0006950

response to stress

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR019805
InterPro:IPR001404

P

From MGI

GO:0009986

cell surface

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P34058

C

From MGI

GO:0016234

inclusion body

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P34058

C

From MGI

GO:0016323

basolateral plasma membrane

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P34058

C

From MGI

GO:0016324

apical plasma membrane

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P34058

C

From MGI

GO:0017098

sulfonylurea receptor binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P34058

F

From MGI

GO:0019901

protein kinase binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P34058

F

From MGI

GO:0031526

brush border membrane

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P34058

C

From MGI

GO:0032092

positive regulation of protein binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P34058

P

From MGI

GO:0032564

dATP binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P34058

F

From MGI

GO:0033160

positive regulation of protein import into nucleus, translocation

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P34058

P

From MGI

GO:0043524

negative regulation of neuron apoptotic process

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P34058

P

From MGI

GO:0044325

ion channel binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P34058

F

From MGI

GO:0045793

positive regulation of cell size

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P34058

P

From MGI

GO:0051082

unfolded protein binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR019805
InterPro:IPR001404

F

From MGI

GO:0071902

positive regulation of protein serine/threonine kinase activity

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P34058

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Voss AK et al. (2000) Mice lacking HSP90beta fail to develop a placental labyrinth. Development 127: 1-11 PubMed GONUTS page
  2. Davies TH et al. (2002) A new first step in activation of steroid receptors: hormone-induced switching of FKBP51 and FKBP52 immunophilins. J Biol Chem 277: 4597-600 PubMed GONUTS page
  3. Piwien-Pilipuk G et al. (2002) Impairment of mineralocorticoid receptor (MR)-dependent biological response by oxidative stress and aging: correlation with post-translational modification of MR and decreased ADP-ribosylatable level of elongating factor 2 in kidney cells. J Biol Chem 277: 11896-903 PubMed GONUTS page
  4. Rallu M et al. (1997) Function and regulation of heat shock factor 2 during mouse embryogenesis. Proc Natl Acad Sci U S A 94: 2392-7 PubMed GONUTS page
  5. Cheng A et al. (2007) A role for AGL ubiquitination in the glycogen storage disorders of Lafora and Cori's disease. Genes Dev 21: 2399-409 PubMed GONUTS page
  6. Mootha VK et al. (2003) Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria. Cell 115: 629-40 PubMed GONUTS page
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