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MGI:Hsf4

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Hsf4 ( synonyms: ldis1 )
Protein Name(s) heat shock transcription factor 4,
External Links
MGI MGI:1347058

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000122

negative regulation of transcription from RNA polymerase II promoter

MGI:MGI:3821682
PMID:18755693[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3057199

P

From MGI

GO:0001654

eye development

MGI:MGI:3056236
PMID:15343150[2]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3056560

P

From MGI

GO:0003677

DNA binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0238

F

From MGI

GO:0003700

sequence-specific DNA binding transcription factor activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR000232

F

From MGI

GO:0005634

nucleus

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_001099647

C

From MGI

GO:0006351

transcription, DNA-dependent

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0804

P

From MGI

GO:0006355

regulation of transcription, DNA-dependent

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0805

P

From MGI

GO:0006355

regulation of transcription, DNA-dependent

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR000232

P

From MGI

GO:0006950

response to stress

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0346

P

From MGI

GO:0008284

positive regulation of cell proliferation

MGI:MGI:3056833
PMID:15483628[3]

IGI: Inferred from Genetic Interaction

MGI:MGI:96238

P

From MGI

GO:0008284

positive regulation of cell proliferation

MGI:MGI:3056833
PMID:15483628[3]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3057199

P

From MGI

GO:0033169

histone H3-K9 demethylation

MGI:MGI:3821682
PMID:18755693[1]

IDA: Inferred from Direct Assay

P

From MGI

GO:0043010

camera-type eye development

MGI:MGI:3056833
PMID:15483628[3]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3057199

P

From MGI

GO:0043565

sequence-specific DNA binding

MGI:MGI:3821682
PMID:18755693[1]

IDA: Inferred from Direct Assay

F

From MGI

GO:0043565

sequence-specific DNA binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_001099647

F

From MGI

GO:0045597

positive regulation of cell differentiation

MGI:MGI:3056833
PMID:15483628[3]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3057199

P

From MGI

GO:0045944

positive regulation of transcription from RNA polymerase II promoter

MGI:MGI:3821682
PMID:18755693[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3057199

P

From MGI

GO:0048468

cell development

MGI:MGI:3526483
PMID:15593327[4]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3527211

P

From MGI

GO:0051260

protein homooligomerization

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_001099647

P

From MGI

GO:0070207

protein homotrimerization

MGI:MGI:3821682
PMID:18755693[1]

IDA: Inferred from Direct Assay

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 1.4 Fujimoto M et al. (2008) Analysis of HSF4 binding regions reveals its necessity for gene regulation during development and heat shock response in mouse lenses. J Biol Chem 283: 29961-70 PubMed GONUTS page
  2. Jablonski MM et al. (2004) The ldis1 lens mutation in RIIIS/J mice maps to chromosome 8 near cadherin 1. Mol Vis 10: 577-87 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 Fujimoto M et al. (2004) HSF4 is required for normal cell growth and differentiation during mouse lens development. EMBO J 23: 4297-306 PubMed GONUTS page
  4. Min JN et al. (2004) Unique contribution of heat shock transcription factor 4 in ocular lens development and fiber cell differentiation. Genesis 40: 205-17 PubMed GONUTS page
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