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MGI:Hrg

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Hrg ( synonyms: D16JH2, D18020 )
Protein Name(s) histidine-rich glycoprotein,
External Links
MGI MGI:2146636

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0004867

serine-type endopeptidase inhibitor activity

MGI:MGI:3789419
PMID:15869579[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3789962

F

From MGI

GO:0004869

cysteine-type endopeptidase inhibitor activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR000010

F

From MGI

GO:0005515

protein binding

MGI:MGI:3530701
PMID:15748999[2]

IPI: Inferred from Physical Interaction

UniProtKB:Q03350

F

From MGI

GO:0005576

extracellular region

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P04196

C

From MGI

GO:0007596

blood coagulation

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0094

P

From MGI

GO:0007599

hemostasis

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0356

P

From MGI

GO:0008201

heparin binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P04196

F

From MGI

GO:0008270

zinc ion binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P04196

F

From MGI

GO:0010543

regulation of platelet activation

MGI:MGI:3789419
PMID:15869579[1]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0010543

regulation of platelet activation

MGI:MGI:4941083
PMID:21264222[3]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0016525

negative regulation of angiogenesis

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P04196

P

From MGI

GO:0019865

immunoglobulin binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P04196

F

From MGI

GO:0020037

heme binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P04196

F

From MGI

GO:0030168

platelet activation

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P04196

P

From MGI

GO:0030193

regulation of blood coagulation

MGI:MGI:3789419
PMID:15869579[1]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0030193

regulation of blood coagulation

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P04196

P

From MGI

GO:0042730

fibrinolysis

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0280

P

From MGI

GO:0043395

heparan sulfate proteoglycan binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P04196

F

From MGI

GO:0043498

cell surface binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P04196

F

From MGI

GO:0046872

metal ion binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P04196

F

From MGI

GO:0050832

defense response to fungus

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P04196

P

From MGI

GO:0050832

defense response to fungus

MGI:MGI:5294287
PMID:18797515[4]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0051918

negative regulation of fibrinolysis

MGI:MGI:3789419
PMID:15869579[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3789962

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 Tsuchida-Straeten N et al. (2005) Enhanced blood coagulation and fibrinolysis in mice lacking histidine-rich glycoprotein (HRG). J Thromb Haemost 3: 865-72 PubMed GONUTS page
  2. Simantov R et al. (2005) The antiangiogenic effect of thrombospondin-2 is mediated by CD36 and modulated by histidine-rich glycoprotein. Matrix Biol 24: 27-34 PubMed GONUTS page
  3. Ringvall M et al. (2011) Enhanced platelet activation mediates the accelerated angiogenic switch in mice lacking histidine-rich glycoprotein. PLoS One 6: e14526 PubMed GONUTS page
  4. Rydengård V et al. (2008) Histidine-rich glycoprotein protects from systemic Candida infection. PLoS Pathog 4: e1000116 PubMed GONUTS page
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